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Author Details

Rajeev Vibhakar
Center for Cancer and Blood Disorders, Children's Hospital Colorado.
1997
102
36
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37934854Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high-grade glioma.Neuro Oncol2024
36639156Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.J Immunother Cancer2023
37486991EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.Neuro Oncol2023
37124531A novel preclinical model of craniospinal irradiation in pediatric diffuse midline glioma demonstrates decreased metastatic disease.Front Oncol2023
37114557Targeting B7â¿¿H3 through EZH2 inhibition in MYCâ¿¿positive Group 3 medulloblastoma.Oncol Rep2023
36747867Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy.bioRxiv2023
36915612The PARP inhibitor Rucaparib synergizes with radiation to attenuate atypical teratoid rhabdoid tumor growth.Neurooncol Adv2023
34077540Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.Neuro Oncol2022
35406445SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma.Cancers (Basel)2022
35344040Venetoclax Cooperates with Ionizing Radiation to Attenuate Diffuse Midline Glioma Tumor Growth.Clin Cancer Res2022
35814855Radiation Therapy for Young Children Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant for Primary Brain Tumors.Adv Radiat Oncol2022
35618754Author Correction: scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.Nat Commun2022
36446943Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36131014Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
35179215Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors.Int J Oncol2022
35143643Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels.Blood2022
34477871A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.Neuro Oncol2022
34021242Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile.Commun Biol2021
33494392A Regulatory Loop of FBXW7-MYC-PLK1 Controls Tumorigenesis of MYC-Driven Medulloblastoma.Cancers (Basel)2021
33910002Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma.Cell Rep2021
33601323Bromodomain and extra-terminal inhibitors-A consensus prioritisation after the Paediatric Strategy Forum for medicinal product development of epigenetic modifiers in children-ACCELERATE.Eur J Cancer2021
33741928The transcriptional landscape of Shh medulloblastoma.Nat Commun2021
33844835The long noncoding RNA lnc-HLX-2-7 is oncogenic in Group 3 medulloblastomas.Neuro Oncol2021
33749791NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.J Neuropathol Exp Neurol2021
34409497Subgroup and subtype-specific outcomes in adult medulloblastoma.Acta Neuropathol2021
34545084Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.Nat Commun2021
33984150Converging evidence for inhibition of transcriptional control in high-grade gliomas.Neuro Oncol2021
31594826Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma.Mol Cancer Ther2020
31969682Correction: BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.Oncogene2020
31844250BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.Oncogene2020
31755223Medulloblastoma has a global impact on health related quality of life: Findings from an international cohort.Cancer Med2020
33086074Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.Cell Rep2020
33063010Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas.Neurooncol Adv2020
32743560Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma.Cell Rep Med2020
32783945Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.Cell Rep2020
32642704Proteasome inhibition as a therapeutic approach in atypical teratoid/rhabdoid tumors.Neurooncol Adv2020
32642682Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine.Neurooncol Adv2020
32180106Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine.J Neurooncol2020
32145124MiR-1253 exerts tumor-suppressive effects in medulloblastoma via inhibition of CDK6 and CD276 (B7-H3).Brain Pathol2020
32268092Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma.Cell Rep2020
32567728The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme.Mol Carcinog2020
32195191Increased HDAC Activity and c-MYC Expression Mediate Acquired Resistance to WEE1 Inhibition in Acute Leukemia.Front Oncol2020
32129445Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors.Neuro Oncol2020
31595628Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.Pediatr Blood Cancer2020
30626740Combined functional genomic and chemical screens identify SETD8 as a therapeutic target in MYC-driven medulloblastoma.JCI Insight2019
31863004scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.Nat Commun2019
31664194Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.Nature2019
30230537Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.Int J Cancer2019
31382461Role of MYC-miR-29-B7-H3 in Medulloblastoma Growth and Angiogenesis.J Clin Med2019
31515514Effect of early-stage autophagy inhibition in BRAF<sup>V600E</sup> autophagy-dependent brain tumor cells.Cell Death Dis2019
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Wilmer Eye Institute, Johns Hopkins Medical Institutions
Co-authored papers 11
Erasmus MC Cancer Institute, University Medical Center Rotterdam
Co-authored papers 11
Erasmus MC Cancer Institute
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Kitasato University School of Medicine
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Heersink School of Medicine, University of Alabama at Birmingham
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