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Author Details

Xiaowei Zhuang
Howard Hughes Medical Institute, Harvard University
1994
193
84
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36580914Molecular and spatial signatures of mouse brain aging at single-cell resolution.Cell2023
37905044Detecting time-varying genetic effects in Alzheimer's disease using a longitudinal GWAS model.bioRxiv2023
38092916A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain.Nature2023
38092912Molecularly defined and spatially resolved cell atlas of the whole mouse brain.Nature2023
36993643Inference of single cell profiles from histology stains with the Single-Cell omics from Histology Analysis Framework (SCHAF).bioRxiv2023
37080778Topological reorganization of functional hubs in patients with Parkinson's disease with freezing of gait.J Neuroimaging2023
36945367A molecularly defined and spatially resolved cell atlas of the whole mouse brain.bioRxiv2023
37172568Spatially resolved epigenomic profiling of single cells in complex tissues.Cell2023
37034735A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain.bioRxiv2023
36272405Spatially resolved epigenomic profiling of single cells in complex tissues.Cell2022
35680881Proteomic and functional analyses of the periodic membrane skeleton in neurons.Nat Commun2022
35771910Conservation and divergence of cortical cell organization in human and mouse revealed by MERFISH.Science2022
35676482A preoptic neuronal population controls fever and appetite during sickness.Nature2022
37214176High-content CRISPR screening.Nat Rev Methods Primers2022
36104283Longitudinal Changes in Cognitive Functioning and Brain Structure in Professional Boxers and Mixed Martial Artists After They Stop Fighting.Neurology2022
33408406Spatially resolved single-cell genomics and transcriptomics by imaging.Nat Methods2021
33828471Brain Entropy During Aging Through a Free Energy Principle Approach.Front Hum Neurosci2021
34616063Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH.Nature2021
34663959Decoding molecular and cellular heterogeneity of mouse nucleus accumbens.Nat Neurosci2021
34417516Tetra-gel enables superior accuracy in combined super-resolution imaging and expansion microscopy.Sci Rep2021
34711971Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram.Nat Methods2021
34093115Energy-Period Profiles of Brain Networks in Group fMRI Resting-State Data: A Comparison of Empirical Mode Decomposition With the Short-Time Fourier Transform and the Discrete Wavelet Transform.Front Neurosci2021
34035045Characterizing spatial gene expression heterogeneity in spatially resolved single-cell transcriptomic data with nonuniform cellular densities.Genome Res2021
34087162Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.Cancer Cell2021
34002095CTCF mediates dosage- and sequence-context-dependent transcriptional insulation by forming local chromatin domains.Nat Genet2021
32451507m<sup>6</sup>A-binding YTHDF proteins promote stress granule formation.Nat Chem Biol2020
31811979A robust deep neural network for denoising task-based fMRI data: An application to working memory and episodic memory.Med Image Anal2020
32105612Lamina-Dependent Stretching and Unconventional Chromosome Compartments in Early C. elegans Embryos.Mol Cell2020
31882528Unique white matter structural connectivity in early-stage drug-naive Parkinson disease.Neurology2020
33362704Resting-State Static and Dynamic Functional Abnormalities in Active Professional Fighters With Repetitive Head Trauma and With Neuropsychological Impairments.Front Neurol2020
32822575Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin.Cell2020
32592530A technical review of canonical correlation analysis for neuroscience applications.Hum Brain Mapp2020
32898682Disentangling time series between brain tissues improves fMRI data quality using a time-dependent deep neural network.Neuroimage2020
32615255Single-scale time-dependent window-sizes in sliding-window dynamic functional connectivity analysis: A validation study.Neuroimage2020
32123490MCLENA-1: A Phase II Clinical Trial for the Assessment of Safety, Tolerability, and Efficacy of Lenalidomide in Patients with Mild Cognitive Impairment Due to Alzheimer's Disease.Open Access J Clin Trials2020
32474081CAST: A multi-scale convolutional neural network based automated hippocampal subfield segmentation toolbox.Neuroimage2020
31085639Imaging-based pooled CRISPR screening reveals regulators of lncRNA localization.Proc Natl Acad Sci U S A2019
31562479Voices in methods development.Nat Methods2019
31501331Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression.Proc Natl Acad Sci U S A2019
31467223Membrane-associated periodic skeleton is a signaling platform for RTK transactivation in neurons.Science2019
31209033βII-spectrin promotes mouse brain connectivity through stabilizing axonal plasma membranes and enabling axonal organelle transport.Proc Natl Acad Sci U S A2019
31262725Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters.J Cell Biol2019
31403734Understanding white matter structural connectivity differences between cognitively impaired and nonimpaired active professional fighters.Hum Brain Mapp2019
31316204Rotation tracking of genome-processing enzymes using DNA origami rotors.Nature2019
31481928Sex Moderates Amyloid and Apolipoprotein ε4 Effects on Default Mode Network Connectivity at Rest.Front Neurol2019
30743154Neural correlates of distinct cognitive phenotypes in early Parkinson's disease.J Neurol Sci2019
31042147Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration.Elife2019
30894332Multivariate group-level analysis for task fMRI data with canonical correlation analysis.Neuroimage2019
30772280Altered functional network topology correlates with clinical measures in very early-stage, drug-naïve Parkinson's disease.Parkinsonism Relat Disord2019
30979890Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling.Nat Commun2019
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Collaborators

Jeffrey R Moffitt
Harvard Medical School
Co-authored papers 14
Melike Lakadamyali
Center for Engineering Mechanobiology, University of Pennsylvania
Co-authored papers 9
Bo Huang
University of California san francisco
Co-authored papers 9
Alistair N Boettiger
Co-authored papers 7
Guisheng Zhong
ShanghaiTech University
Co-authored papers 6
Charles Bernick
Cleveland Clinic Lou Ruvo Center for Brain Health
Co-authored papers 6
Shixin Liu
The Rockefeller University
Co-authored papers 5
Hongkui Zeng
Allen Institute for Brain Science
Co-authored papers 5
Zizhen Yao
Allen Institute for Brain Science
Co-authored papers 5
Brian J Beliveau
Co-authored papers 4
Peng Yin
Wyss Institute for Biologically Inspired Engineering, Harvard University
Co-authored papers 4
Aviv Regev
Broad Institute of MIT and Harvard
Co-authored papers 4
Edward S Boyden
McGovern Institute for Brain Research
Co-authored papers 3
Brent Bluett
Stanford University
Co-authored papers 3
Loren L Looger
Howard Hughes Medical Institute
Co-authored papers 3
Carol L Thompson
Allen Institute for Brain Science
Co-authored papers 2
Swetansu K Hota
Gladstone Institutes
Co-authored papers 2
Orit Rozenblatt-Rosen
Co-authored papers 2
Jay Shendure
University of Washington
Co-authored papers 2
Lydia Ng
Allen Institute for Brain Science
Co-authored papers 2
Anish Bhaswanth Chakka
Co-authored papers 2
Zoltan Mari
Lou Ruvo Center for Brain Health, Cleveland Clinic Nevada
Co-authored papers 2
Cindy T J van Velthoven
Allen Institute for Brain Science
Co-authored papers 2
Jeff Goldy
Co-authored papers 2
Michael Hawrylycz
Allen Institute for Brain Science
Co-authored papers 2
Tim Dolbeare
Allen Institute for Brain Science
Co-authored papers 2
Feng Zhang
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 2
Alex K Shalek
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
Co-authored papers 1
Clifford P Brangwynne
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Joshua Gould
Co-authored papers 1
Release 1.2