Author details

Full Name

Derek Klarin

Affiliation

ORCID

Career Start Year

2012

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37034679	Admixture Mapping of Peripheral Artery Disease in a Dominican Population Reveals a Novel Risk Locus on 2q35.	medRxiv	2023
37600667	Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35.	Front Genet	2023
38012230	Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.	Nat Commun	2023
37286573	Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.	Nat Commun	2023
36949957	<i>TP53-</i>mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease.	Nat Cardiovasc Res	2023
37323297	Circulating proteins and peripheral artery disease risk: observational and Mendelian randomization analyses.	Eur Heart J Open	2023
37308786	Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program.	Nat Genet	2023
36734038	Plasma protein and venous thromboembolism: prospective cohort and mendelian randomisation analyses.	Br J Haematol	2023
34811547	Clinical utility of polygenic risk scores for coronary artery disease.	Nature Reviews Cardiology	2022
35654975	A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.	Nat Genet	2022
36154123	Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors.	Circulation	2022
35915156	Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.	Nat Med	2022
35234888	Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study.	Hum Mol Genet	2022
35199555	Diastolic Blood Pressure Alleles Improve Congenital Heart Defect Repair Outcomes.	Circ Res	2022
35186008	Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci.	Front Genet	2022
34543263	Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins.	PLoS Genetics	2021
33853351	Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease.	Arterioscler Thromb Vasc Biol	2021
34110906	Genetic Determinants of Peripheral Artery Disease.	Circ Res	2021
34110897	Epidemiology and Genetics of Venous Thromboembolism and Chronic Venous Disease.	Circ Res	2021
34002035	Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis.	Int J Obes (Lond)	2021
34265237	Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm.	Am J Hum Genet	2021
34139859	Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease.	Circulation	2021
33822779	Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.	PLoS Genet	2021
33356394	Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.	Hypertension	2021
32847391	Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease-Brief Report.	Arterioscler Thromb Vasc Biol	2021
34547901	A Missense Variant in the IL-6 Receptor and Protection From Peripheral Artery Disease.	Circ Res	2021
33166319	PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.	PLoS One	2020
32067876	Concomitant carotid endarterectomy and cardiac surgery does not decrease postoperative stroke rates.	J Vasc Surg	2020
32300774	Genetic predisposition to smoking in relation to 14 cardiovascular diseases.	Eur Heart J	2020
32226016	Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study.	PLoS Genet	2020
32981348	Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.	Circulation	2020
32915777	The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study.	PLoS Med	2020
33280006	Erratum to: Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache.	Int J Epidemiol	2020
31481659	Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.	Nat Commun	2019
31738818	Association of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease.	JAMA	2019
31727424	Long-Term Cardiovascular Risk inÂ WomenÂ With Hypertension DuringÂ Pregnancy.	J Am Coll Cardiol	2019
30389748	DNA Sequence Variation in <i>ACVR1C</i> Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.	Diabetes	2019
31285632	Genome-wide association study of peripheral artery disease in the Million Veteran Program.	Nat Med	2019
31451708	Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.	Nat Commun	2019
31420334	Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.	Blood	2019
31070453	Genetic Association of Finger Photoplethysmography-Derived Arterial Stiffness Index With Blood Pressure and Coronary Artery Disease.	Arterioscler Thromb Vasc Biol	2019
31337231	Association of <i>APOL1</i> Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program.	Circulation	2019
30940813	Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.	Nat Commun	2019
31101824	Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.	Nat Commun	2019
29804741	Risk factor profile and anatomic features of previously asymptomatic patients presenting with carotid-related stroke.	J Vasc Surg	2018
28982690	Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.	Circulation	2018
30275531	Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.	Nat Genet	2018
29691411	Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.	Nat Commun	2018
28196256	Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease.	JAMA - Journal of the American Medical Association	2017
28434606	Reply.	Journal of Vascular Surgery	2017