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Author Details

Alicja Trocha
Ragon Institute of MGH
1991
90
55
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37217466Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.Nat Commun2023
37217466Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.Nat Commun2023
35159122A Leucine Zipper Dimerization Strategy to Generate Soluble T Cell Receptors Using the <i>Escherichia coli</i> Expression System.Cells2022
35960796A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.Sci Adv2022
35364330Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19.Clin Immunol2022
35159122A Leucine Zipper Dimerization Strategy to Generate Soluble T Cell Receptors Using the <i>Escherichia coli</i> Expression System.Cells2022
35364330Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19.Clin Immunol2022
35960796A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.Sci Adv2022
34260940HLA class-I-peptide stability mediates CD8<sup>+</sup> T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.Cell Rep2021
33791730Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19.medRxiv2021
34265281Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses.Cell2021
34260940HLA class-I-peptide stability mediates CD8<sup>+</sup> T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.Cell Rep2021
34781741HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy.mBio2021
34433692Profound Treg perturbations correlate with COVID-19 severity.Proc Natl Acad Sci U S A2021
33791730Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19.medRxiv2021
34433692Profound Treg perturbations correlate with COVID-19 severity.Proc Natl Acad Sci U S A2021
34781741HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy.mBio2021
34265281Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses.Cell2021
32900948Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes.Proc Natl Acad Sci U S A2020
32877699Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19.Cell2020
32900948Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes.Proc Natl Acad Sci U S A2020
33330871Profound Treg perturbations correlate with COVID-19 severity.bioRxiv2020
33330871Profound Treg perturbations correlate with COVID-19 severity.bioRxiv2020
32877699Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19.Cell2020
31048489Structural topology defines protective CD8<sup>+</sup> T cell epitopes in the HIV proteome.Science2019
31048489Structural topology defines protective CD8<sup>+</sup> T cell epitopes in the HIV proteome.Science2019
29355843Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.J Clin Invest2018
29355843Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.J Clin Invest2018
27992415A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Nat Genet2017
28878089HLA-B*14:02-Restricted Env-Specific CD8<sup>+</sup> T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection.J Virol2017
28060008Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 and presence of heme oxygenase-1-specific regulatory T cells.AIDS2017
27992415A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Nat Genet2017
28100831Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.Sci Transl Med2017
28100831Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.Sci Transl Med2017
28878089HLA-B*14:02-Restricted Env-Specific CD8<sup>+</sup> T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection.J Virol2017
28060008Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 and presence of heme oxygenase-1-specific regulatory T cells.AIDS2017
27082643A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.PLoS Pathog2016
27173934HIV-1 Vpu Mediates HLA-C Downregulation.Cell Host Microbe2016
27082643A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.PLoS Pathog2016
27938646Increased frequencies of CD8<sup>+</sup>CD57<sup>+</sup> T cells are associated with antibody neutralization breadth against HIV in viraemic controllers.J Int AIDS Soc2016
27938646Increased frequencies of CD8<sup>+</sup>CD57<sup>+</sup> T cells are associated with antibody neutralization breadth against HIV in viraemic controllers.J Int AIDS Soc2016
27173934HIV-1 Vpu Mediates HLA-C Downregulation.Cell Host Microbe2016
25717111Anti-APOBEC3G activity of HIV-1 Vif protein is attenuated in elite controllers.J Virol2015
25717111Anti-APOBEC3G activity of HIV-1 Vif protein is attenuated in elite controllers.J Virol2015
26269189The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers.J Virol2015
26269189The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers.J Virol2015
24498287Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacity.PLoS One2014
24498287Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacity.PLoS One2014
25165115HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes.J Virol2014
25122219Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.PLoS Pathog2014
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Collaborators

Bruce D Walker
Ragon Institute of Mass General
Co-authored papers 78
Florencia Pereyra
Co-authored papers 23
Marcus Altfeld
Co-authored papers 16
Marylyn M Addo
Co-authored papers 13
Todd M Allen
Co-authored papers 13
Andrew E Rosenberg
Co-authored papers 12
Ildiko Toth
Co-authored papers 10
Chanson J Brumme
Co-authored papers 9
Mary Carrington
Frederick National Laboratory for Cancer Research, National Cancer Institute
Co-authored papers 8
Brian L Block
Co-authored papers 8
David Heckerman
Co-authored papers 7
Brett Baker
Co-authored papers 7
Otto O Yang
Co-authored papers 7
Hendrik Streeck
Co-authored papers 5
Donna Marie L Alvino
Co-authored papers 5
Douglas S Kwon
Ragon Institute of MGH
Co-authored papers 5
Almas Rathod
Co-authored papers 5
Seanna Vine
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Wilfredo F Garcia-Beltran
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Daniel E Cohen
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Robert F Siliciano
Johns Hopkins University School of Medicine
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Alissa C Rothchild
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Jonathan M Carlson
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Carl Kadie
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Bette Korber
Co-authored papers 3
Ryan J Park
Keck School of Medicine, University of Southern California
Co-authored papers 3
Dylan Koundakjian
The Robert Larner M.D. College of Medicine, University of Vermont
Co-authored papers 3
Elizabeth J Rossin
Co-authored papers 3
Kenneth H Mayer
Co-authored papers 3
Sylvie Le Gall
Co-authored papers 3
Release 1.2