Author details

Full Name

James Todd Auman

Affiliation

ORCID

Career Start Year

1994

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36709390	Sequencing of genes of drug response in tumor DNA and implications for precision medicine in cancer patients.	Pharmacogenomics J	2023
37214853	Adopting Duplex Sequencingâ¿¢ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.	bioRxiv	2023
35805068	Differentiation Trajectory of Limbal Stem and Progenitor Cells under Normal Homeostasis and upon Corneal Wounding.	Cells	2022
32958699	Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance).	Clin Cancer Res	2021
29996866	Intrinsic molecular subtypes of breast cancers categorized as HER2-positive using an alternative chromosome 17 probe assay.	Breast Cancer Res	2018
30026228	VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma.	Science	2018
30397360	Genetic variation determines VEGF-A plasma levels in cancer patients.	Sci Rep	2018
28297679	Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.	Cell Rep	2017
28658632	Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.	Cell Rep	2017
30009279	Exceptional Chemotherapy Response in Metastatic Colorectal Cancer Associated With Hyper-Indel-Hypermutated Cancer Genome and Comutation of POLD1 and MLH1.	JCO Precis Oncol	2017
26536169	Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.	N Engl J Med	2016
26061751	Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.	N Engl J Med	2015
26134224	Functional FLT1 Genetic Variation is a Prognostic Factor for Recurrence in Stage I-III Non-Small-Cell Lung Cancer.	J Thorac Oncol	2015
22824796	Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas.	Oncogene	2013
23047291	A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.	Pharmacogenet Genomics	2012
21865292	Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity.	Toxicological Sciences	2011
21573211	Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees.	PLoS One	2011
20017668	Institutional profile. UNC Institute for Pharmacogenomics and Individualized Therapy: interdisciplinary research for individual care.	Pharmacogenomics	2010
20727737	Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy.	Eur J Cancer	2010
21280375	Gene therapy: Have the risks associated with viral vectors been solved?		2010
20712522	Cancer pharmacogenomics: do cancer cell lines have the right stuff?	Pharmacogenomics	2010
20047974	Now's the time to find biomarkers on purpose.	Ann Oncol	2010
20100687	Colorectal cancer cell lines lack the molecular heterogeneity of clinical colorectal tumors.	Clin Colorectal Cancer	2010
18653328	Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation.	Eur J Cancer	2008
19051132	Applications of genomic tools to colorectal cancer therapeutics.	Curr Opin Mol Ther	2008
19018720	Race does not explain genetic heterogeneity in pharmacogenomic pathways.	Pharmacogenomics	2008
18570634	Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype.	Genome Biol	2008
18464047	Cancer pharmacogenomics: DNA genotyping and gene expression profiling to identify molecular determinants of chemosensitivity.	Drug Metab Rev	2008
17450226	Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.	Environmental Health Perspectives	2007
17652165	Heat map visualization of high-density clinical chemistry data.	Physiological Genomics	2007
15781589	Differential gene expression profiling in whole blood during acute systemic inflammation in lipopolysaccharide-treated rats.	Physiol Genomics	2005
12682213	Ontogenesis of beta-adrenoceptor signaling: implications for perinatal physiology and for fetal effects of tocolytic drugs.	Journal of Pharmacology and Experimental Therapeutics	2003
12069947	Are developing beta-adrenoceptors able to desensitize? Acute and chronic effects of beta-agonists in neonatal heart and liver.	American Journal of Physiology - Regulatory Integrative and Comparative Physiology	2002
11959676	beta-Adrenergic modulation of muscarinic cholinergic receptor expression and function in developing heart.	American Journal of Physiology - Regulatory Integrative and Comparative Physiology	2002
11882347	Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain.	Developmental Brain Research	2002
12376418	Beta-adrenoceptor control of G protein function in the neonate: determinant of desensitization or sensitization.	American Journal of Physiology - Regulatory Integrative and Comparative Physiology	2002
11292450	Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats.	Brain Research	2001
11705775	Beta-adrenoceptor-mediated cell signaling in the neonatal heart and liver: responses to terbutaline.	American Journal of Physiology - Regulatory Integrative and Comparative Physiology	2001
11557613	Regulation of fetal cardiac and hepatic beta-adrenoceptors and adenylyl cyclase signaling: terbutaline effects.	American Journal of Physiology - Regulatory Integrative and Comparative Physiology	2001
10837889	Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: implications for neurotoxicity.	Developmental Brain Research	2000
7820615	Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra.	Brain Research	1994