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Author Details

Lawrence H Boise
Winship Cancer Institute, Emory University
1988
184
64
PMIDPaper TitleJournal TitlePublished Year
37767768Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma.Blood Cancer Discov2024
37934799ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma.Blood Cancer Discov2024
37729611Integrated epigenetic and transcriptional single-cell analysis of t(11;14) multiple myeloma and its BCL2 dependency.Blood2024
36861343In vivo characterization of the critical interaction between the RNA exosome and the essential RNA helicase Mtr4 in Saccharomyces cerevisiae.G3 (Bethesda)2023
37526080Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy.J Clin Invest2023
37956312Statin-induced Mitochondrial Priming Sensitizes Multiple Myeloma Cells to BCL2 and MCL-1 Inhibitors.Cancer Res Commun2023
37237081Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.Nat Cancer2023
35927247Venetoclax ex vivo functional profiling predicts improved progression-free survival.Blood Cancer J2022
35511673β adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma.Haematologica2022
35380688PDZ Proteins SCRIB and DLG1 Regulate Myeloma Cell Surface CD86 Expression, Growth, and Survival.Mol Cancer Res2022
35565356Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients.Cancers (Basel)2022
35357482Agent myeloma has a new weapon from (ch1)Q.Blood2022
36170375Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma.Sci Adv2022
33275813Natural history of multiple myeloma patients refractory to venetoclax: A single center experience.Am J Hematol2021
33738338Oncolytic herpes simplex virus infects myeloma cells <i>in vitro</i> and <i>in vivo</i>.Mol Ther Oncolytics2021
33737856BCL2 Family Inhibitors in the Biology and Treatment of Multiple Myeloma.Blood Lymphat Cancer2021
33649772Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression.Blood2021
33731701Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer.Nat Commun2021
33731366Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma.Clin Cancer Res2021
33634031Game of Bones: How Myeloma Manipulates Its Microenvironment.Front Oncol2021
34638271Keeping Myeloma in Check: The Past, Present and Future of Immunotherapy in Multiple Myeloma.Cancers (Basel)2021
34778800Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.Blood Cancer Discov2021
33406420Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins.Cell Rep2021
33368455Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma.Am J Hematol2021
32286263Clinical features and survival of multiple myeloma patients harboring t(14;16) in the era of novel agents.Blood Cancer J2020
32579940CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival.Cell Rep2020
32739887BCL2 dependency in diffuse large B-cell lymphoma: it's a family affair.Haematologica2020
32685011TGF-β causes Docetaxel resistance in Prostate Cancer via the induction of Bcl-2 by acetylated KLF5 and Protein Stabilization.Theranostics2020
32144272Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.Nat Commun2020
32298201Long-Term Follow-Up Results of Lenalidomide, Bortezomib, and Dexamethasone Induction Therapy and Risk-Adapted Maintenance Approach in Newly Diagnosed Multiple Myeloma.J Clin Oncol2020
30332496Survival outcomes of patients with primary plasma cell leukemia (pPCL) treated with novel agents.Cancer2019
31698452Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma.Blood Adv2019
31767829Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone.Blood Cancer J2019
31582370Myeloma's sound of silencing.Blood2019
31405035Cancer Metabolism and the Evasion of Apoptotic Cell Death.Cancers (Basel)2019
31231360Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma.Front Immunol2019
31043428Stromal Support of Metabolic Function through Mitochondrial Transfer in Multiple Myeloma.Cancer Res2019
31013254Early alterations in stem-like/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy.JCI Insight2019
31090928Clinical efficacy of daratumumab, pomalidomide, and dexamethasone in patients with relapsed or refractory myeloma: Utility of re-treatment with daratumumab among refractory patients.Cancer2019
31023594Immunotherapy in Multiple Myeloma: Accelerating on the Path to the Patient.Clin Lymphoma Myeloma Leuk2019
30679802Functional profiling of venetoclax sensitivity can predict clinical response in multiple myeloma.Leukemia2019
30480777Safety and survival outcomes for bloodless transplantation in patients with myeloma.Cancer2019
30701088The prodomain of caspase-3 regulates its own removal and caspase activation.Cell Death Discov2019
2892424014-3-3ζ binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors.Leukemia2018
30190351A miRaculous new therapy in myeloma?Blood2018
30033091MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation.Cancer Cell2018
30004825Myocarditis With Radiotherapy and Immunotherapy in Multiple Myeloma.J Oncol Pract2018
29775995Phosphorylation alters Bim-mediated Mcl-1 stabilization and priming.FEBS J2018
27878989Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors.FEBS Lett2017
28089569Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth.Cell Metab2017
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Collaborators

Co-authored papers 52
Emory University School of Medicine
Co-authored papers 22
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University of Pennsylvania Department of Pathology & Laboratory Medicine
Co-authored papers 5
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University at Albany
Co-authored papers 2
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Universite de Montreal
Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
Johns Hopkins School of Medicine
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Weill Cornell School of Medicine
Co-authored papers 2
University of Warwick
Co-authored papers 2
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 2
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Co-authored papers 2
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 2
CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay
Co-authored papers 2
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Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
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University of Pennsylvania
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Instituto Universitario de Oncologia, Universidad de Oviedo
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New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 2
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Armed Forces Radiobiology Research Institute
Co-authored papers 2
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 2