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Author Details

Nirmala Akula
National Institutes of Health
2002
59
25
PMIDPaper TitleJournal TitlePublished Year
36824922Association of Polygenic Score and the involvement of Cholinergic and Glutamatergic Pathways with Lithium Treatment Response in Patients with Bipolar Disorder.Res Sq2023
37528149Exome-wide association study of treatment-resistant depression suggests novel treatment targets.Sci Rep2023
38077040Exploring the genetics of lithium response in bipolar disorders.Res Sq2023
37886563Lithium Response in Bipolar Disorder is Associated with Focal Adhesion and PI3K-Akt Networks: A Multi-omics Replication Study.Res Sq2023
37192167Aneuploidy effects on human gene expression across three cell types.Proc Natl Acad Sci U S A2023
37037607Cellular Diversity in Human Subgenual Anterior Cingulate and Dorsolateral Prefrontal Cortex by Single-Nucleus RNA-Sequencing.J Neurosci2023
37433967Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder.Mol Psychiatry2023
37461719Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder.Res Sq2023
36932057Antipsychotic drug use complicates assessment of gene expression changes associated with schizophrenia.Transl Psychiatry2023
35225756Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach.Br J Psychiatry2022
35505515Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM.Br J Psychiatry2022
35817769Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.Transl Psychiatry2022
33441847Prediction of lithium response using genomic data.Sci Rep2021
36408127Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study.Complex Psychiatry2021
33558674Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders.Neuropsychopharmacology2021
34497278HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders.Sci Rep2021
34845190Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.Transl Psychiatry2021
30837454Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.Transl Psychiatry2019
30135510Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness.Mol Psychiatry2019
29956436Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.Bipolar Disord2019
29121268Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.JAMA Psychiatry2018
29904359Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.Front Psychiatry2018
30552317Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.Transl Psychiatry2018
29039254The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.J Psychopharmacol2017
26211730An Integrative Genomic Study Implicates the Postsynaptic Density in the Pathogenesis of Bipolar Disorder.Neuropsychopharmacology2016
27329760Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.Hum Mol Genet2016
26806518Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.Lancet2016
25730879Rare variants in neuronal excitability genes influence risk for bipolar disorder.Proc Natl Acad Sci U S A2015
22404658Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder.World J Biol Psychiatry2014
24393808RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.Mol Psychiatry2014
22182935Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.Mol Psychiatry2013
24123842Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm.Am J Med Genet B Neuropsychiatr Genet2013
23827886Race, genetic ancestry and response to antidepressant treatment for major depression.Neuropsychopharmacology2013
23840348Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report.PLoS One2013
23377668Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.J Immunother2013
21383773Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling.Pharmacogenomics J2012
22948381Replication and meta-analysis of TMEM132D gene variants in panic disorder.Transl Psychiatry2012
22771240Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.Biol Psychiatry2012
20351719Genetic variation in cholinergic muscarinic-2 receptor gene modulates M2 receptor binding in vivo and accounts for reduced binding in bipolar disorder.Mol Psychiatry2011
22373213Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives.BMC Proc2011
21915301A network-based approach to prioritize results from genome-wide association studies.PLoS One2011
21547870A systems approach to the biology of mood disorders through network analysis of candidate genes.Pharmacopsychiatry2011
21339755A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study.Mol Psychiatry2011
21249187Accuracy of CNV Detection from GWAS Data.PLoS One2011
20081856Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.Nat Genet2010
20453537The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment.Neuropsychobiology2010
20215924A genome-wide association study of amygdala activation in youths with and without bipolar disorder.J Am Acad Child Adolesc Psychiatry2010
19088739Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder.Mol Psychiatry2009
19589501Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans.Biol Psychiatry2009
19724244Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients.Pharmacogenet Genomics2009
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Collaborators

Francis J McMahon
National Institute of Mental Health, National Institutes of Health
Co-authored papers 50
Thomas G Schulze
SUNY Upstate Medical University
Co-authored papers 31
Marcella Rietschel
Central Institute of Mental Health, University of Mannheim
Co-authored papers 25
Markus M N??then
Institute of Human Genetics, University Hospital Bonn
Co-authored papers 23
Sven Cichon
University Hospital Basel and University of Basel
Co-authored papers 23
Gonzalo Laje
Gothenburg University.
Co-authored papers 23
Layla Kassem
National Institute of Mental Health, National Institutes of Health
Co-authored papers 22
John R Kelsoe
University of California
Co-authored papers 21
Liping Hou
Harrison International Peace Hospital
Co-authored papers 21
Andreas Reif
University Hospital Frankfurt am Main
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Jay Raymond DePaulo
Johns Hopkins University School of Medicine
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Caterina Chillotti
"San Giovanni di Dio" Hospital
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Alessio Squassina
Universita degli Studi Di Cagliari.
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Giovanni Severino
University of Cagliari.
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Mirko Manchia
University of Cagliari
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Piotr M Czerski
Poznan University of Medical Sciences
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Janusz K Rybakowski
Poznan University of Medical Sciences
Co-authored papers 19
Joanna Hauser
Poznan University of Medical Sciences
Co-authored papers 19
Maria Del Zompo
University of Cagliari.
Co-authored papers 19
Raffaella Ardau
Hospital University Agency of Cagliari.
Co-authored papers 19
James B Potash
University Hospital Frankfurt
Co-authored papers 19
Sarah Kittel-Schneider
University Hospital Frankfurt am Main, University Hospital Wurzburg
Co-authored papers 19
Guy A Rouleau
McGill University, Canada Montreal Neurological Institute and Hospital
Co-authored papers 19
Mark A Frye
The Mayo Clinic
Co-authored papers 18
St??phane Jamain
INSERM
Co-authored papers 18
Susan G Leckband
VA San Diego Healthcare System
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Frank Bellivier
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Lina Martinsson
Karolinska Institutet.
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