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Author Details

Alysson R Muotri
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
1999
190
56
PMIDPaper TitleJournal TitlePublished Year
35339359Brain organoids, consciousness, ethics and moral status.Semin Cell Dev Biol2023
37588663Editorial: Advances in iPSC technology for disease modeling and therapeutic applications.Front Cell Dev Biol2023
37496118Brain Model Technology and Its Implications.Camb Q Healthc Ethics2023
37256873Effects of acute low-moderate dose ionizing radiation to human brain organoids.PLoS One2023
36925616First Organoid Intelligence (OI) workshop to form an OI community.Front Artif Intell2023
36586137Cortical brain organoid as a model to study microgravity exposure.Artif Organs2023
36638789ISSCR Education Committee syllabus and learning guide for enhancing stem cell literacy.Stem Cell Reports2023
36734369Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition.Genet Mol Biol2023
36893252Comment on "Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals".Science2023
35981907Network and Microcircuitry Development in Human Brain Organoids.Biol Psychiatry2023
35948659Advancing preclinical models of psychiatric disorders with human brain organoid cultures.Mol Psychiatry2023
36385168Impact of alcohol exposure on neural development and network formation in human cortical organoids.Mol Psychiatry2023
36115764The impact of antidepressants on human neurodevelopment: Brain organoids as experimental tools.Semin Cell Dev Biol2023
34389807"Archealization" of human brain organoids.Neuropsychopharmacology2022
35350244Neurodevelopment in Children Exposed to Zika <i>in utero</i>: Clinical and Molecular Aspects.Front Genet2022
35706057Genome-wide translation control analysis of developing human neurons.Mol Brain2022
35768728Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex.Nat Genet2022
35501322Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content.Nat Commun2022
35654974A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex.Nat Genet2022
36406234Recent advancements and future requirements in vascularization of cortical organoids.Front Bioeng Biotechnol2022
36572698Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex.Nat Commun2022
36109452Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder.Neurotherapeutics2022
36202289Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids.Neurobiol Dis2022
36171373A nomenclature consensus for nervous system organoids and assembloids.Nature2022
36327326SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir.PLoS Biol2022
36253345Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations.Transl Psychiatry2022
34957478Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model.Brain2022
33414364Transcription factor 4 and its association with psychiatric disorders.Transl Psychiatry2021
33574182Reintroduction of the archaic variant of <i>NOVA1</i> in cortical organoids alters neurodevelopment.Science2021
33727673Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.Mol Psychiatry2021
33501759Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids.EMBO Mol Med2021
33888873Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy.Mol Psychiatry2021
34648331Response to Comment on "Reintroduction of the archaic variant of <i>NOVA1</i> in cortical organoids alters neurodevelopment".Science2021
34433918Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism.Mol Psychiatry2021
34465892Mapping the hotspots for DNA repair synthesis in human brain organoids.Cell Death Differ2021
34816099Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells.iScience2021
34548630Correction: Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism.Mol Psychiatry2021
34688299Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities.Orphanet J Rare Dis2021
33942547Brain organoids: A promising model to assess oxidative stress-induced central nervous system damage.Dev Neurobiol2021
34215735Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration.NPJ Parkinsons Dis2021
34122014All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors.Front Cell Neurosci2021
34010654MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling.Cell Rep2021
34083786Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB.Nat Neurosci2021
34021639High gestational folic acid supplementation prevents hypoxia-ischemia-induced caspase-3 augmenting without changing synapsin and H3 methylation levels in the rat hippocampus.Int J Dev Neurosci2021
33431633The Logic of Developing Neocortical Circuits in Health and Disease.J Neurosci2021
33276121Reprogramming the brain in and out of diseased states.Mol Cell Neurosci2021
32499560Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions.Cell Res2020
31956038Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin α<sub>v</sub>β<sub>5</sub> Axis.Cell Stem Cell2020
33192333Editorial: Brain Organoids: Modeling in Neuroscience.Front Cell Neurosci2020
33137567Methadone interrupts neural growth and function in human cortical organoids.Stem Cell Res2020
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Collaborators

Cleber A Trujillo
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 28
Priscilla D Negraes
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 21
Gabriel G Haddad
university of california san diego
Co-authored papers 12
Gene W Yeo
University of California
Co-authored papers 11
Jonathan Sebat
University of California San Diego
Co-authored papers 9
John R Yates
TheScripps Research Institute
Co-authored papers 7
Wei Wu
University of California
Co-authored papers 6
Nicole G Coufal
University of California
Co-authored papers 6
Eric Courchesne
University of California
Co-authored papers 5
Karen Pierce
University of California
Co-authored papers 5
Joseph G Gleeson
University of California
Co-authored papers 4
Keith K Vaux
university of california san diego Health Physician Network
Co-authored papers 4
Daniel B McClatchy
Co-authored papers 3
Anna Devor
Boston University
Co-authored papers 3
Roger S Lasken
J. Craig Venter Institute
Co-authored papers 3
Tracy A Bedrosian
Institute for Genomic Medicine, Nationwide Children's Hospital
Co-authored papers 3
Helen Zhao
Co-authored papers 3
Caroline M Nievergelt
VA San Diego Healthcare System (VASDHS)
Co-authored papers 3
Bradley Voytek
Alfred P. Sloan Foundation, National Academy of Sciences, University of California Berkeley, University of California San Diego, University of California, San Diego
Co-authored papers 3
Spencer M Moore
University of Arizona College of Medicine
Co-authored papers 3
Dan Zhou
Co-authored papers 3
Lorenz Studer
The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Jacob Ellegood
Hospital for Sick Children
Co-authored papers 2
Isaac A Chaim
University of California San Diego
Co-authored papers 2
Ole A Andreassen
Oslo University Hospital & Institute of Clinical Medicine, University of Oslo
Co-authored papers 2
Allen Wang
Center for Epigenomics, University of California San Diego School of Medicine
Co-authored papers 2
Matthieu Vandenberghe
Oslo University Hospital
Co-authored papers 2
Vikas Duvvuri
University of California San Diego
Co-authored papers 2
Richard Gao
University of Tubingen
Co-authored papers 2
Orit Poulsen
Co-authored papers 2
Release 1.2