Author details

Full Name

Bram P Prins

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36991119	An atlas of genetic scores to predict multi-omic traits.	Nature	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37034613	Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric Disorders.	Res Sq	2023
36712066	Trans-ethnic Polygenic Risk Scores for Body Mass Index: An International Hundred K+ Cohorts Consortium Study.	medRxiv	2023
36824751	Genetic mechanisms of 184 neuro-related proteins in human plasma.	medRxiv	2023
37450379	Trans-ethnic genomic informed risk assessment for Alzheimer's disease: An International Hundred K+ Cohorts Consortium study.	Alzheimers Dement	2023
36253349	Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.	Nat Commun	2022
35387486	Genetic Landscape of the ACE2 Coronavirus Receptor.	Circulation	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
33517400	Genome-wide association study of circulating interleukin 6 levels identifies novel loci.	Hum Mol Genet	2021
33851187	Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.	medRxiv	2021
33946982	Advances in Genomic Discovery and Implications for Personalized Prevention and Medicine: Estonia as Example.	J Pers Med	2021
33837377	Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.	Nat Med	2021
33727701	Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2021
33230300	Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2020
32041957	Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age.	Nat Commun	2020
33067605	Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.	Nat Metab	2020
31152163	A catalog of genetic loci associated with kidney function from analyses of a million individuals.	Nat Genet	2019
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
30175238	Meta-analysis of exome array data identifies six novel genetic loci for lung function.	Wellcome Open Res	2018
30071838	Combination therapy as a potential risk factor for the development of type 2 diabetes in patients with schizophrenia: the GOMAP study.	BMC Psychiatry	2018
29875488	Genomic atlas of the human plasma proteome.	Nature	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
30012220	Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.	Genome Biol	2018
29874175	ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals.	Circ Genom Precis Med	2018
30429575	Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
30388399	Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.	Am J Hum Genet	2018
30470734	Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia.	Translational Psychiatry	2018
30224653	Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
29748316	Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval.	Circ Genom Precis Med	2018
29506594	Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study.	Twin Res Hum Genet	2018
28082375	Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.	Int J Epidemiol	2017
28379579	Discovery of novel heart rate-associated loci using the Exome Chip.	Hum Mol Genet	2017
28887542	Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations.	Scientific Reports	2017
28739976	Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.	Hypertension	2017
29125842	Evaluating the glucose raising effect of established loci via a genetic risk score.	PLoS One	2017
28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Nat Genet	2017
27978545	Eosinophil Count Is a Common Factor for Complex Metabolic and Pulmonary Traits and Diseases: The LifeLines Cohort Study.	PLoS One	2016
26803157	lodGWAS: a software package for genome-wide association analysis of biomarkers with a limit of detection.	Bioinformatics	2016
27327646	Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.	PLoS Med	2016
27659466	52 Genetic Loci Influencing MyocardialÂ Mass.	J Am Coll Cardiol	2016
25691538	Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study.	Cardiovasc Res	2015
25752597	In Silico Post Genome-Wide Association Studies Analysis of C-Reactive Protein Loci Suggests an Important Role for Interferons.	Circ Cardiovasc Genet	2015
24951663	Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.	Circ Cardiovasc Genet	2014
24395754	QCGWAS: A flexible R package for automated quality control of genome-wide association results.	Bioinformatics	2014
23022100	Discovery and fine mapping of serum protein loci through transethnic meta-analysis.	Am J Hum Genet	2012
22698794	Genetics of coronary artery disease: genome-wide association studies and beyond.	Atherosclerosis	2012
21953487	Beyond genome-wide association studies: new strategies for identifying genetic determinants of hypertension.	Curr Hypertens Rep	2011
20351714	Poor replication of candidate genes for major depressive disorder using genome-wide association data.	Mol Psychiatry	2011
22001757	Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.	Nat Genet	2011