Author details

Full Name

Leszek J Klimczak

Affiliation

National Institute of Environmental Health Sciences (NIEHS)

ORCID

Career Start Year

1984

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36697836	Author Correction: The repertoire of mutational signatures in human cancer.	Nature	2023
37078607	Changes in metabolic landscapes shape divergent but distinct mutational signatures and cytotoxic consequences of redox stress.	Nucleic Acids Res	2023
37471042	Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans.	Nucleic Acids Res	2023
33444353	UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin.	PLoS Genet	2021
34493867	Genomic and evolutionary classification of lung cancer in never smokers.	Nat Genet	2021
32133535	Mutation signatures specific to DNA alkylating agents in yeast and cancers.	Nucleic Acids Res	2020
32025018	The repertoire of mutational signatures in human cancer.	Nature	2020
33006981	Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic.	PLoS One	2020
32719516	APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis.	Nat Genet	2020
32793907	Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic.	bioRxiv	2020
32922147	Mixture Analyses of Air-sampled Pollen Extracts Can Accurately Differentiate Pollen Taxa.	Atmos Environ (1994)	2020
32277034	Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases.	Proc Natl Acad Sci U S A	2020
32142506	Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.	PLoS Biol	2020
31067233	Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature.	PLoS Biol	2019
31658304	Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies.	PLoS Pathog	2019
31568516	Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.	PLoS Biol	2019
30537516	Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.	Cancer Cell	2018
30096301	Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.	Cell	2018
29136510	Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.	Cancer Cell	2017
28988769	Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.	Cell	2017
27788131	The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.	PLoS Genet	2016
26258849	An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers.	Nat Genet	2015
26527001	APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions.	Cell Rep	2015
23852170	An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.	Nat Genet	2013
22607975	Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.	Mol Cell	2012
18724869	Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray.	BMC Genomics	2008
12769629	Novel directions in antipsychotic target identification using gene arrays.	Curr Drug Targets CNS Neurol Disord	2002
10458993	Origin, targeting, and function of the apicomplexan plastid.	Curr Opin Microbiol	1999
9061951	An enzyme similar to animal type II photolyases mediates photoreactivation in Arabidopsis.	Plant Cell	1997
7480353	Multiple isoforms of Arabidopsis casein kinase I combine conserved catalytic domains with variable carboxyl-terminal extensions.	Plant Physiol	1995
7696877	Reconstitution of Arabidopsis casein kinase II from recombinant subunits and phosphorylation of transcription factor GBF1.	Plant Cell	1995
12232253	Microheterogeneous Cytosolic High-Mobility Group Proteins from Broccoli Co-Purify with and Are Phosphorylated by Casein Kinase II.	Plant Physiol	1994
8328968	Purification and characterization of casein kinase I from broccoli.	Biochem J	1993
1525562	DNA binding activity of the Arabidopsis G-box binding factor GBF1 is stimulated by phosphorylation by casein kinase II from broccoli.	Plant Cell	1992
16667406	Biochemical Similarities between Soluble and Membrane-Bound Calcium-Dependent Protein Kinases of Barley.	Plant Physiol	1990
36654100	Purification and characterization of DNA polymerase from the archaebacterium Methanobacterium thermoautotrophicum.	Biochemistry	1986
3927262	Purification and characterization of DNA polymerase from the archaebacterium Sulfolobus acidocaldarius.	Nucleic Acids Res	1985
24177802	Isolation and characterization of mitochondrial DNA of the oomycetous fungus Phytophthora infestans.	Curr Genet	1984

1 - 38 of 38

Nozomu Yachie

The University of British Columbia

Career Start Year 2006

Number of shared co-authors 1

Vera van Noort

Leiden University, Institute of Biology Leiden

Career Start Year 2003

Number of shared co-authors 0

Karen Moore

University of Exeter

Career Start Year 2000

Number of shared co-authors 0

Navdeep Gill

Nova Southeastern University

Career Start Year 1998

Number of shared co-authors 1

V??ctor Quesada

Instituto Universitario de Oncologia, Universidad de Oviedo

Career Start Year 1998

Number of shared co-authors 11

Vincent Magrini

The Ohio State University

Career Start Year 1997

Number of shared co-authors 1

Jamal S M Sabir

King Abdulaziz University

Career Start Year 1997

Number of shared co-authors 0

Anna Shevchenko

Max Plank Institute of Molecular Cell Biology and Genetics

Career Start Year 1996

Number of shared co-authors 1

Ping Liang

College of Chemistry and Chemical Engineering, Hunan University

Career Start Year 1995

Number of shared co-authors 1

Dirk Walther

Max Planck Institute of Molecular Plant Physiology

Career Start Year 1995

Number of shared co-authors 0

Timothy T Harkins

NVIDIA Corporation

Career Start Year 1994

Number of shared co-authors 4

Martijn A Huynen

Radboud University Medical Centre Nijmegen

Career Start Year 1992

Number of shared co-authors 2

Sean R McCorkle

Brookhaven National Laboratory

Career Start Year 1992

Number of shared co-authors 0

Martin Pospisek

Charles University

Career Start Year 1991

Number of shared co-authors 0

Arcady Mushegian

National Science Foundation

Career Start Year 1991

Number of shared co-authors 0

Istv??n Nagy

Institute of Biochemistry, HUN-REN Biological Research Centre

Career Start Year 1991

Number of shared co-authors 0

Muh-Ching Yee

Stanford University

Career Start Year 1988

Number of shared co-authors 0

Aled M Edwards

University of Toronto

Career Start Year 1984

Number of shared co-authors 1

Opher Gileadi

Structural Genomics Consortium Karolinska Institute Stockholm Sweden.

Career Start Year 1984

Number of shared co-authors 0

Hediye Erdjument-Bromage

Neuroscience Institute, NYU Grossman School of Medicine

Career Start Year 1984

Number of shared co-authors 0

Bruce W Birren

Broad Institute of MIT and Harvard

Career Start Year 1983

Number of shared co-authors 7

Brian J Haas

Broad Institute of MIT and Harvard

Career Start Year 1981

Number of shared co-authors 6

Neil D Clarke

Yale-NUS College Singapore

Career Start Year 1981

Number of shared co-authors 0

Kalappa Muniyappa

Indian Institute of Science

Career Start Year 1979

Number of shared co-authors 0

Ryuji Kobayashi

Tokyo University of Science

Career Start Year 1979

Number of shared co-authors 1

Norma Neff

Stanford University

Career Start Year 1974

Number of shared co-authors 0

David Botstein

Calico Life Sciences LLC

Career Start Year 1968

Number of shared co-authors 3

Ronald W Davis

Stanford University

Career Start Year 1968

Number of shared co-authors 1

David Schlessinger

NIH/National Institute of Ageing

Career Start Year 1960

Number of shared co-authors 9

Thomas E Wilson

University of Michigan ann arbor

Career Start Year 1955

Number of shared co-authors 0

row(s) 1 - 30 of 30

Dmitry A Gordenin

National Institute of Environmental Health Sciences (NIEHS)

Co-authored papers 24

Natalie Saini

Medical University of South Carolina

Co-authored papers 14

Piotr A Mieczkowski

Co-authored papers 7

Jaegil Kim

Co-authored papers 5

Steven A Roberts

Co-authored papers 5

Gad Getz

Broad Institute of the Massachusetts Institute of Technology and Harvard

Co-authored papers 4

Ludmil B Alexandrov

Moores Cancer Center, university of california san diego

Co-authored papers 3

Nuria Lopez-Bigas

Universitat Pompeu Fabra

Co-authored papers 3

Akinyemi I Ojesina

University of Alabama at Birmingham

Co-authored papers 2

Shepherd H Schurman

Clinical Research Unit, National Institute on Aging

Co-authored papers 2

Toshinori Hinoue

Co-authored papers 2

Rehan Akbani

The University of Texas MD Anderson Cancer Center

Co-authored papers 2

Kyle R Covington

Baylor College of Medicine

Co-authored papers 2

Gregory V Kryukov

Co-authored papers 2

Katherine A Hoadley

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill

Co-authored papers 2

Bogdan Czerniak

University of Texas MD Anderson Cancer Center

Co-authored papers 2

Nikolaus Schultz

Memorial Sloan Kettering Cancer Center

Co-authored papers 2

Peter W Laird

Van Andel Institute

Co-authored papers 2

Victor E Reuter

Memorial Sloan Kettering Cancer Center

Co-authored papers 2

Kristen Leraas

Nationwide Children's Hospital

Co-authored papers 2

Chandra Sekhar Pedamallu

Broad Institute

Co-authored papers 2

Francisco Vega

The University of Texas MD Anderson Cancer Center

Co-authored papers 2

David J McConkey

Johns Hopkins School of Medicine

Co-authored papers 2

Mauro A A Castro

Federal University of Parana

Co-authored papers 2

Ville Mustonen

University of Helsinki

Co-authored papers 2

Gordon B Mills

Knight Cancer Institute, Oregon Health and Sciences University

Co-authored papers 2

Susan Bullman

Fred Hutchinson Cancer Center

Co-authored papers 2

Matthew Meyerson

Broad Institute

Co-authored papers 2

Catherine J Wu

Co-authored papers 2

Amy G Robertson

Present address: Dxige Research Inc.

Co-authored papers 2

1 - 30

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