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Author Details

Thomas J Ketas
1998
77
45
PMIDPaper TitleJournal TitlePublished Year
36865101Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.2023
36334723Longitudinal antibody response kinetics following SARS-CoV-2 messenger RNA vaccination in pregnant and nonpregnant persons.American journal of obstetrics & gynecology MFM2023
37903160Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.2023
37563124SARS-CoV-2 vaccination, booster, and infection in pregnant population enhances passive immunity in neonates.Nat Commun2023
37384638Exposure of progressive immune dysfunction by SARS-CoV-2 mRNA vaccination in patients with chronic lymphocytic leukemia: A prospective cohort study.2023
37244989Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.2023
34669426The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization.Journal of Virology2022
35932217Asthma 17q21 polymorphism associates with decreased risk of COVID-19 in children.Pediatric Pulmonology2022
36597532SARS-CoV-2 mRNA vaccination exposes progressive adaptive immune dysfunction in patients with chronic lymphocytic leukemia.2022
34390501Serologic response to mRNA COVID-19 vaccination in lymphoma patients.Am J Hematol2021
33524125Postconvalescent SARS-CoV-2 IgG and Neutralizing Antibodies are Elevated in Individuals with Poor Metabolic Health.J Clin Endocrinol Metab2021
33515984Testing-on-a-probe biosensors reveal association of early SARS-CoV-2 total antibodies and surrogate neutralizing antibodies with mortality in COVID-19 patients.Biosensors and Bioelectronics2021
34193339Predictors of Nonseroconversion after SARS-CoV-2 Infection.Emerg Infect Dis2021
34136730Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.Pathog Immun2021
33438580High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination.eLife2021
33758842Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva.bioRxiv2021
33236020Testing-on-a-probe biosensors reveal association of early SARS-CoV-2 total antibodies and surrogate neutralizing antibodies with mortality in COVID-19 patients.2020
32393800T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.Nat Med2020
33521696Convalescent plasma-mediated resolution of COVID-19 in a patient with humoral immunodeficiency.Cell Rep Med2020
31537780Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.Nat Commun2019
30487280Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.J Virol2019
29150937cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.Biotechnol Bioeng2018
29669838Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers .Journal of Virology2018
29474444Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.PLoS Pathog2018
28834745Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.Cell Rep2017
28539451Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers.J Virol2017
27627672Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.PLoS Pathog2016
27467575Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.PLoS Pathog2016
26246566Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.Journal of Virology2015
25589637A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.J Virol2015
26311893Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.J Virol2015
26089353HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.Science2015
24767177Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies.Retrovirology2014
23109186Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220.Journal of Antimicrobial Chemotherapy2013
24068931A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.PLoS Pathog2013
22018634Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors.Virology2012
22330914Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.Antimicrobial Agents and Chemotherapy2012
22524614Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array.Journal of the American Chemical Society2012
22666328A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity.PLoS ONE2012
22520838Effects of sequence changes in the HIV-1 gp41 fusion peptide on CCR5 inhibitor resistance.Virology2012
21690411Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody.Proceedings of the National Academy of Sciences of the United States of America2011
21356539Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41.Virology2011
20629537Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.Journal of Infectious Diseases2010
19648924HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits.Nature Immunology2009
19410272Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.Virology2009
19303620Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities.Virology2009
19297617Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency.Proceedings of the National Academy of Sciences of the United States of America2009
19289833Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41.Proceedings of the National Academy of Sciences of the United States of America2009
19706443Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers.Proceedings of the National Academy of Sciences of the United States of America2009
18647836Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249.Proceedings of the National Academy of Sciences of the United States of America2008
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