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Author Details

Andreas Lennartsson
Karolinska Institute
2003
51
25
PMIDPaper TitleJournal TitlePublished Year
38036629The exon-junction complex helicase eIF4A3 holds therapeutic potential in acute myeloid leukemia.Leukemia2024
36350659EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes.Nucleic Acids Res2023
37495775Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells.Leukemia2023
34666848<i>Sirtuins</i> and <i>neuropeptide y</i> downregulation in Flinders Sensitive Line rat model of depression.Acta Neuropsychiatr2022
36232714RUNX1/CEBPA Mutation in Acute Myeloid Leukemia Promotes Hypermethylation and Indicates for Demethylation Therapy.Int J Mol Sci2022
34968247One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies.Epigenomes2021
33591326Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML.Blood Adv2021
33670267The Role of Non-Catalytic Domains of Hrp3 in Nucleosome Remodeling.Int J Mol Sci2021
32232485AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding.Blood2020
31900031A regulatory role for CHD2 in myelopoiesis.Epigenetics2020
31669559Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies.Exp Hematol2019
28003272Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.Blood2017
28427179Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease.Oncotarget2017
28445158The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo.Oncotarget2017
29383137Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes.Oncotarget2017
29152069The transcriptional coregulator <i>NAB2</i> is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells.Oncotarget2017
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
28923166Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria.Elife2017
27794045Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals.Nucleic Acids Res2017
27612989Distinct global binding patterns of the Wilms tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells.Haematologica2017
26829670External signals shape the epigenome.Genome Biol2016
26959885Mutations in histone modulators are associated with prolonged survival during azacitidine therapy.Oncotarget2016
25789315The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia.Biomed Res Int2015
26673794Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.Epigenetics Chromatin2015
26153137EpiFactors: a comprehensive database of human epigenetic factors and complexes.Database (Oxford)2015
26118500Epigenetic aberrations in acute myeloid leukemia: Early key events during leukemogenesis.Exp Hematol2015
25678556Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.Science2015
25621013Transcription-coupled recruitment of human CHD1 and CHD2 influences chromatin accessibility and histone H3 and H3.3 occupancy at active chromatin regions.Epigenetics Chromatin2015
25717144Technical Advance: Transcription factor, promoter, and enhancer utilization in human myeloid cells.J Leukoc Biol2015
24671951High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesis.Blood2014
25216995The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.Mol Cancer2014
24866170Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.Epigenetics2014
24670763An atlas of active enhancers across human cell types and tissues.Nature2014
24670764A promoter-level mammalian expression atlas.Nature2014
24686393microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia.Epigenetics2014
24671952Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation.Blood2014
23652932Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression.Transl Psychiatry2013
24073922Forced expression of the DEK-NUP214 fusion protein promotes proliferation dependent on upregulation of mTOR.BMC Cancer2013
23871158Leukemia associated mutant Wilms' tumor gene 1 protein promotes expansion of human hematopoietic progenitor cells.Leuk Res2013
21682946Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression.Int J Neuropsychopharmacol2012
28183376Epigenetic alterations related to early life stressful events.Acta Neuropsychiatr2012
21960591Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks.Blood2011
20237505Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.Leukemia2010
19168116Histone modification patterns and epigenetic codes.Biochim Biophys Acta2009
19377474The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.Nat Genet2009
16282362Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein.Am J Physiol Gastrointest Liver Physiol2006
16684888All-trans retinoic acid-induced expression of bactericidal/permeability-increasing protein (BPI) in human myeloid cells correlates to binding of C/EBPbeta and C/EBPepsilon to the BPI promoter.J Leukoc Biol2006
15590754A murine antibacterial ortholog to human bactericidal/permeability-increasing protein (BPI) is expressed in testis, epididymis, and bone marrow.J Leukoc Biol2005
16019164The proximal promoter of the human cathepsin G gene conferring myeloid-specific expression includes C/EBP, c-myb and PU.1 binding sites.Gene2005
15642667Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model.Haematologica2005
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Collaborators

Karl Ekwall
Karolinska Institute
Co-authored papers 14
Hideya Kawaji
RIKEN Center for Integrative Medical Sciences
Co-authored papers 9
Piero Carninci
RIKEN Center for Integrative Medical Sciences
Co-authored papers 9
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 9
Timo Lassmann
Telethon Kids Institute, University of Western Australia
Co-authored papers 8
Yoshihide Hayashizaki
Center for Integrative Medical Sciences
Co-authored papers 8
Erik Arner
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 8
Albin Sandelin
University of Copenhagen
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Masayoshi Itoh
RIKEN Center for Integrative Medical Sciences
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Robin Andersson
University of Copenhagen
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Jessica Severin
Center for Integrative Medical Sciences
Co-authored papers 6
David A Hume
Mater Research Institute-UQ, Translational Research Institute
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Carsten O Daub
International Institute of Molecular and Cell Biology in Warsaw
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Björn Nilsson
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Finn Drabl??s
NTNU - Norwegian University of Science and Technology
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Jun Kawai
RIKEN Center for Integrative Medical Sciences
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Michael Rehli
University Hospital Regensburg
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Harukazu Suzuki
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Takeya Kasukawa
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Yulia A Medvedeva
Research Center of Biotechnology RAS, Russian Academy of Sciences
Co-authored papers 5
Marina Lizio
Cerevance Ltd
Co-authored papers 5
Michelle R??nnerblad
Karolinska Institutet
Co-authored papers 4
Geoffrey J Faulkner
Mater Research Institute - University of Queensland
Co-authored papers 4
Jayson Harshbarger
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Tsugumi Kawashima
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Yuri Ishizu
RIKEN Center for Life Science Technologies
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Yasushi Okazaki
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Miki Kojima
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Release 1.2