Author details

Full Name

Jennifer J Westendorf

Affiliation

ORCID

Career Start Year

1993

Papers

161

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36850434	Atomic Force Microscopy Micro-Indentation Methods for Determining the Elastic Modulus of Murine Articular Cartilage.	Sensors (Basel)	2023
37802020	Pulling rank with RNA: RANKL promotes the association of PGC-1Î²/RNA complexes with NCoR/HDAC3 to activate gene expression in osteoclasts.		2023
35314385	GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice.		2022
36063372	Gender and Geographic Origin as Determinants of Manuscript Publication Outcomes: JBMRÂ® Bibliometric Analysis from 2017 to 2019.	J Bone Miner Res	2022
35922466	MicroRNA-101a enhances trabecular bone accrual in male mice.	Sci Rep	2022
34686856	The Musculoskeletal Knowledge Portal: improving access to multi-omics data.	Nat Rev Rheumatol	2022
33434347	Pleckstrin homology (PH) domain and Leucine Rich Repeat Phosphatase 1 (Phlpp1) Suppresses Parathyroid Hormone Receptor 1 (Pth1r) Expression and Signaling During Bone Growth.	Journal of Bone and Mineral Research	2021
33860007	Precise detection of a murine germline mutation of the gene associated with kyphosis and developmental disorders.	Journal of Advanced Veterinary and Animal Research	2021
33559841	Single Cell Omics for Musculoskeletal Research.	Current Osteoporosis Reports	2021
33602789	GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.	Cancer Res	2021
34086369	Pleckstrin homology (PH) domain and leucine rich repeat phosphatase 1 (Phlpp1) suppresses parathyroid hormone receptor 1 (Pth1r) expression and signaling during bone growth.	Journal of Bone and Mineral Research	2021
33155137	Histone Mutations and Bone Cancers.	Advances in Experimental Medicine and Biology	2021
35047830	An activating germline <i>IDH1</i> variant associated with a tumor entity characterized by unilateral and bilateral chondrosarcoma of the mastoid.	HGG Adv	2020
32267012	The importance of diversity, equity, and inclusion in orthopedic research.	Journal of Orthopaedic Research	2020
32332097	Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2.	Journal of Biological Chemistry	2020
33454009	Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL.	Journal of Biological Chemistry	2020
33311522	Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1.	Scientific Reports	2020
32845524	Bringing Genomic Discoveries to the Clinic: Integrating Omic Data Into the Musculoskeletal Field Through International Teamwork and Collaboration.	J Bone Miner Res	2020
32777102	The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community.	J Bone Miner Res	2020
31189651	Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice.	Journal of Biological Chemistry	2019
31582730	Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice.	Cell Death and Disease	2019
29782940	Defining osteoblast and adipocyte lineages in the bone marrow.		2019
30977555	Epigenetics as a New Frontier in Orthopedic Regenerative Medicine and Oncology.	Journal of Orthopaedic Research	2019
31415114	Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways.	Journal of Bone and Mineral Research	2019
31537378	Lung tumor cells inhibit bone mineralization and osteoblast activity.	Biochemical and Biophysical Research Communications	2019
29775231	DNA methylation and FoxO3a regulate PHLPP1 expression in chondrocytes.	Journal of Cellular Biochemistry	2018
28840938	Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity.	Journal of Cellular Physiology	2018
29914885	Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis.	Journal of Immunology	2018
30327434	Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development.	Journal of Biological Chemistry	2018
29989665	Focusing on the Science: JBMR Manuscript Types.	J Bone Miner Res	2018
29899112	Enhancer of zeste homolog 2 () controls bone formation and cell cycle progression during osteogenesis in mice.	Journal of Biological Chemistry	2018
29523594	Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in <i>PTEN</i>- or <i>SPOP</i>-mutated prostate cancer.	EMBO Mol Med	2018
29167276	PTEN Loss Promotes Intratumoral Androgen Synthesis and Tumor Microenvironment Remodeling via Aberrant Activation of RUNX2 in Castration-Resistant Prostate Cancer.	Clin Cancer Res	2018
29068480	Phlpp inhibitors block pain and cartilage degradation associated with osteoarthritis.	Journal of Orthopaedic Research	2018
29544022	The Deletion of Hdac4 in Mouse Osteoblasts Influences Both Catabolic and Anabolic Effects in Bone.	Journal of Bone and Mineral Research	2018
28132772	Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.	Gene	2017
28782836	Histone Deacetylase 3 Deletion in Mesenchymal Progenitor Cells Hinders Long Bone Development.	Journal of Bone and Mineral Research	2017
29212250	Histone deacetylase inhibitors reduce differentiating osteoblast-mediated protection of acute myeloid leukemia cells from cytarabine.	Oncotarget	2017
27662443	Histone deacetylase 3 suppresses Erk phosphorylation and matrix metalloproteinase (Mmp)-13 activity in chondrocytes.	Connective Tissue Research	2017
27516624	Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice.		2017
27507649	Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling.	Science Signaling	2016
27113271	PPP6R3-USP6 amplification: Novel oncogenic mechanism in malignant nodular fasciitis.	Genes Chromosomes Cancer	2016
26746148	Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.	Osteoarthritis and Cartilage	2016
27378743	The synovial microenvironment of osteoarthritic joints alters RNA-seq expression profiles of human primary articular chondrocytes.	Gene	2016
27229140	The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.	Science	2016
26909883	RNA-seq analysis of clinical-grade osteochondral allografts reveals activation of early response genes.	Journal of Orthopaedic Research	2016
27125357	USP6 genetic rearrangements in cellular fibroma of tendon sheath.	Mod Pathol	2016
27402109	Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis.	Current Rheumatology Reports	2016
27454570	Fusion gene profile of biphenotypic sinonasal sarcoma: an analysis of 44 cases.	Histopathology	2016
26484395	Identification of differentially methylated regions in new genes associated with knee osteoarthritis.	Gene	2016