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Author Details

Daniel A Portnoy
University of California berkeley
1981
164
78
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36744898Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes.mBio2023
37905006<i>Listeria monocytogenes</i> utilizes glutathione and limited inorganic sulfur compounds as a source of essential L-cysteine.bioRxiv2023
37695058The major role of <i>Listeria monocytogenes</i> folic acid metabolism during infection is the generation of N-formylmethionine.mBio2023
35316134RibU is an essential determinant of <i>Listeria</i> pathogenesis that mediates acquisition of FMN and FAD during intracellular growth.Proc Natl Acad Sci U S A2022
36317877<i>para</i>-Aminobenzoic Acid Biosynthesis Is Required for Listeria monocytogenes Growth and Pathogenesis.Infect Immun2022
34151776Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons.Elife2021
34407151Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes.PLoS Pathog2021
32185899Why is Listeria monocytogenes such a potent inducer of CD8+ T-cells?Cell Microbiol2020
31936068An Inducible Cre-<i>lox</i> System to Analyze the Role of LLO in <i>Listeria monocytogenes</i> Pathogenesis.Toxins (Basel)2020
31792073The Nonmevalonate Pathway of Isoprenoid Biosynthesis Supports Anaerobic Growth of Listeria monocytogenes.Infect Immun2020
32634175TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes.PLoS Pathog2020
32878997Secondary structure of the mRNA encoding listeriolysin O is essential to establish the replicative niche of <i>L. monocytogenes</i>.Proc Natl Acad Sci U S A2020
32843560(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes.mBio2020
33020211Secretion of c-di-AMP by Listeria monocytogenes Leads to a STING-Dependent Antibacterial Response during Enterocolitis.Infect Immun2020
30511471Listeriolysin O: A phagosome-specific cytolysin revisited.Cell Microbiol2019
31848289A Multiorgan Trafficking Circuit Provides Purifying Selection of Listeria monocytogenes Virulence Genes.mBio2019
31818955Extracellular electron transfer powers flavinylated extracellular reductases in Gram-positive bacteria.Proc Natl Acad Sci U S A2019
31235641A Potent and Effective Suicidal <i>Listeria</i> Vaccine Platform.Infect Immun2019
29279409<i>Listeria monocytogenes</i> triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy.Proc Natl Acad Sci U S A2018
30209391A flavin-based extracellular electron transfer mechanism in diverse Gram-positive bacteria.Nature2018
30118682An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.Mol Cell2018
29902442The Listeriolysin O PEST-like Sequence Co-opts AP-2-Mediated Endocytosis to Prevent Plasma Membrane Damage during Listeria Infection.Cell Host Microbe2018
30038013Recombinant <i>Listeria</i> promotes tumor rejection by CD8<sup>+</sup> T cell-dependent remodeling of the tumor microenvironment.Proc Natl Acad Sci U S A2018
29726107Actin-based motility allows Listeria monocytogenes to avoid autophagy in the macrophage cytosol.Cell Microbiol2018
29719256STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection.Cell Rep2018
27703037Identification of Coxiella burnetii CD8+ T-Cell Epitopes and Delivery by Attenuated Listeria monocytogenes as a Vaccine Vector in a C57BL/6 Mouse Model.J Infect Dis2017
28138025Activity of the Pore-Forming Virulence Factor Listeriolysin O Is Reversibly Inhibited by Naturally Occurring S-Glutathionylation.Infect Immun2017
28097715c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation.Mol Microbiol2017
29042499Activation of the <i>Listeria monocytogenes</i> Virulence Program by a Reducing Environment.mBio2017
28783669Listening to each other: Infectious disease and cancer immunology.Sci Immunol2017
27048798SpoVG Is a Conserved RNA-Binding Protein That Regulates <i>Listeria monocytogenes</i> Lysozyme Resistance, Virulence, and Swarming Motility.mBio2016
27414028An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression.PLoS Pathog2016
27337444Strategies Used by Bacteria to Grow in Macrophages.Microbiol Spectr2016
25535272A prl mutation in SecY suppresses secretion and virulence defects of Listeria monocytogenes secA2 mutants.J Bacteriol2015
26324267Ribosome hibernation facilitates tolerance of stationary-phase bacteria to aminoglycosides.Antimicrob Agents Chemother2015
25892235Host actin polymerization tunes the cell division cycle of an intracellular pathogen.Cell Rep2015
25877890STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.Sci Transl Med2015
25965978RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second Messenger Cyclic di-AMP.J Am Chem Soc2015
26028365The PAMP c-di-AMP Is Essential for Listeria monocytogenes Growth in Rich but Not Minimal Media due to a Toxic Increase in (p)ppGpp. [corrected].Cell Host Microbe2015
25776746Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages.Infect Immun2015
25422304The Listeria monocytogenes hibernation-promoting factor is required for the formation of 100S ribosomes, optimal fitness, and pathogenesis.J Bacteriol2015
25567281Glutathione activates virulence gene expression of an intracellular pathogen.Nature2015
24391507STING-dependent type I IFN production inhibits cell-mediated immunity to Listeria monocytogenes.PLoS Pathog2014
25157076Listeria monocytogenes is resistant to lysozyme through the regulation, not the acquisition, of cell wall-modifying enzymes.J Bacteriol2014
24667708Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity.mBio2014
23716572Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection.mBio2013
22083714Oral infection with signature-tagged Listeria monocytogenes reveals organ-specific growth and dissemination routes in guinea pigs.Infect Immun2012
22451517Development of a single-gene, signature-tag-based approach in combination with alanine mutagenesis to identify listeriolysin O residues critical for the in vivo survival of Listeria monocytogenes.Infect Immun2012
22461646Yogi Berra, Forrest Gump, and the discovery of Listeria actin comet tails.Mol Biol Cell2012
22607800Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages.Cell Host Microbe2012
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Collaborators

University of California berkeley
Co-authored papers 9
University of California berkeley
Co-authored papers 4
Columbia University
Co-authored papers 2
University of California berkeley
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Stanford University
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska
Co-authored papers 1
University of Florida College of Medicine
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Vir Biotechnology Inc.
Co-authored papers 1
Institute of Molecular Biosciences, Goethe University Frankfurt
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
School of Public Health, University of California berkeley
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of Wyoming
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University Of Michigan ann arbor
Co-authored papers 1
University of California Davis
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 1
University of California Berkeley
Co-authored papers 1
Denali Therapeutics Inc.
Co-authored papers 1
University of California berkeley
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Texas A&M University
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes
Co-authored papers 1