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Author Details

Edward P Browne
University of North Carolina at Chapel Hill
2000
39
20
PMIDPaper TitleJournal TitlePublished Year
37808086The Rashomon Importance Distribution: Getting RID of Unstable, Single Model-based Variable Importance.ArXiv2024
36706161A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency.PLoS Pathog2023
38014340Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.bioRxiv2023
36778314Automated microarray for single-cell sorting and collection of lymphocytes following HIV reactivation.bioRxiv2023
36590168Depletion of HIV reservoir by activation of ISR signaling in resting CD4<sup>+</sup>T cells.iScience2022
35853932Towards a comprehensive evaluation of dimension reduction methods for transcriptomic data visualization.Commun Biol2022
35426377Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.J Clin Invest2022
33635929Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors.PLoS Pathog2021
33597266Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.Sci Transl Med2021
33561864SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.Nature2021
32347704Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal.ACS Infect Dis2020
33202596The Role of Toll-Like Receptors in Retroviral Infection.Microorganisms2020
32995766Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801.Res Sq2020
32502335HSF1 Activation Can Restrict HIV Replication.ACS Infect Dis2020
30564891A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression.Cancer Immunol Immunother2019
31409923Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis.Nat Immunol2019
31209404The immune cell landscape in kidneys of patients with lupus nephritis.Nat Immunol2019
30746468Multiplexed enrichment and genomic profiling of peripheral blood cells reveal subset-specific immune signatures.Sci Adv2019
30282021Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency.Cell Rep2018
29996944Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissueArthritis Res Ther2018
28679220Erratum: "Prediction uncertainty and optimal experimental design for learning dynamical systems" [Chaos 26, 063110 (2016)].Chaos2017
27010978A Computational Model of Inhibition of HIV-1 by Interferon-Alpha.PLoS One2016
27363431The effect of HIV-1 Vif polymorphisms on A3G anti-viral activity in an in vivo mouse model.Retrovirology2016
27368775Prediction uncertainty and optimal experimental design for learning dynamical systems.Chaos2016
26912368Visualizing antibody affinity maturation in germinal centers.Science2016
25320301An interleukin-1 beta-encoding retrovirus exhibits enhanced replication in vivo.J Virol2015
24851906Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo.PLoS Pathog2014
23616654Toll-like receptor 7 inhibits early acute retroviral infection through rapid lymphocyte responses.J Virol2013
22207147Removing human immunodeficiency virus (HIV) from human blood using immobilized heparin.Biotechnol Lett2012
22444240Regulation of B-cell responses by Toll-like receptors.Immunology2012
21998589Toll-like receptor 7 controls the anti-retroviral germinal center response.PLoS Pathog2011
19214214Myd88 is required for an antibody response to retroviral infection.PLoS Pathog2009
19304304Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent.Virology2009
18032489Species-specific restriction of apobec3-mediated hypermutation.J Virol2008
16277756Virus-host interactions: new insights from the small RNA world.Genome Biol2005
15069167Evaluation of the host transcriptional response to human cytomegalovirus infection.Physiol Genomics2004
12972646Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells.Proc Natl Acad Sci U S A2003
11711622Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs.J Virol2001
10900033Membrane-destabilizing activity of rotavirus NSP4 is mediated by a membrane-proximal amphipathic domain.J Gen Virol2000
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Collaborators

Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 6
Cynthia Rudin
Duke University
Co-authored papers 4
Soumya Raychaudhuri
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 3
Benjamin Letham
Operations Research Center, Massachusetts Institute of Technology
Co-authored papers 3
Michael B Brenner
Co-authored papers 3
Kamil Slowikowski
Co-authored papers 3
Chad Nusbaum
Co-authored papers 3
Catherine J Wu
Co-authored papers 2
Lisa E Gralinski
University of North Carolina at Chapel Hill
Co-authored papers 2
Ralph S Baric
University of North Carolina
Co-authored papers 2
Portia A Letham
Arizona State University
Co-authored papers 2
Corbin D Jones
University of North Carolina at Chapel Hill
Co-authored papers 2
Chaim Putterman
Albert Einstein College of Medicine
Co-authored papers 2
Alexandra Sch??fer
University of North Carolina at Chapel Hill
Co-authored papers 2
Michelle Petri
Co-authored papers 2
Celine C Berthier
University of Michigan ann arbor
Co-authored papers 2
Matthias Kretzler
University of Michigan ann arbor
Co-authored papers 2
Sarah R Leist
University of North Carolina at Chapel Hill
Co-authored papers 2
Raymond J Pickles
Marsico Lung Institute, University of North Carolina-Chapel Hill
Co-authored papers 2
Scott Steelman
Co-authored papers 2
Brian D Strahl
University of North Carolina
Co-authored papers 2
Jeremy M Simon
University of North Carolina
Co-authored papers 1
Fumitaka Mizoguchi
Co-authored papers 1
Andreas Rechtsteiner
University of California
Co-authored papers 1
Gary S Firestein
Co-authored papers 1
Raghuvar Dronamraju
University of North Carolina at Chapel Hill School of Medicine
Co-authored papers 1
Ronald Swanstrom
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 1
Michael Emerman
Fred Hutchinson Cancer Center
Co-authored papers 1
Steven Henikoff
Fred Hutchinson Cancer Center
Co-authored papers 1
Stuart R Jefferys
Co-authored papers 1
Release 1.2