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Author Details

Matej Vizovi??ek
Jozef Stefan Institute
2013
32
16
PMIDPaper TitleJournal TitlePublished Year
36696904Investigation of osteoclast cathepsin K activity in osteoclastogenesis and bone loss using a set of chemical reagents.Cell Chem Biol2023
37559137Magnetospirillum magneticum triggers apoptotic pathways in human breast cancer cells.Cancer Metab2023
37889671Cathepsin L-mediated EGFR cleavage affects intracellular signalling pathways in cancer.Biol Chem2023
37095140Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins.Commun Biol2023
33687722System-Wide Profiling of Protein Complexes Via Size Exclusion Chromatography-Mass Spectrometry (SEC-MS).Methods Mol Biol2021
33727531Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen.Nat Commun2021
33802262The Tumor Proteolytic Landscape: A Challenging Frontier in Cancer Diagnosis and Therapy.Int J Mol Sci2021
32228244Cysteine cathepsins as therapeutic targets in inflammatory diseases.Expert Opin Ther Targets2020
32601479A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.Sci Rep2020
32870676Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes.J Am Chem Soc2020
32727087Time-Dependent miRNA Profile during Septic Acute Kidney Injury in Mice.Int J Mol Sci2020
32411104Proteolysis of Gingival Keratinocyte Cell Surface Proteins by Gingipains Secreted From <i>Porphyromonas gingivalis</i> - Proteomic Insights Into Mechanisms Behind Tissue Damage in the Diseased Gingiva.Front Microbiol2020
29409929Cysteine cathepsins in extracellular matrix remodeling: Extracellular matrix degradation and beyond.Matrix Biol2019
33855486Characterization of Legumain Degradome Confirms Narrow Cleavage Specificity.Acta Chim Slov2019
31803426Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples.Chem Sci2019
31892161The Acute Phase Response Is a Prominent Renal Proteome Change in Sepsis in Mice.Int J Mol Sci2019
31291060Degradomics in Biomarker Discovery.Proteomics Clin Appl2019
30897858Cysteine Cathepsins and their Extracellular Roles: Shaping the Microenvironment.Cells2019
30652348Menadione-induced apoptosis in U937 cells involves Bid cleavage and stefin B degradation.J Cell Biochem2019
30622175IQGAP-related protein IqgC suppresses Ras signaling during large-scale endocytosis.Proc Natl Acad Sci U S A2019
29719685Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes.Chem Sci2018
30097385Protease Specificity: Towards In Vivo Imaging Applications and Biomarker Discovery.Trends Biochem Sci2018
28733325Protease cleavage site fingerprinting by label-free in-gel degradomics reveals pH-dependent specificity switch of legumain.EMBO J2017
28315251FPPS: Fast Profiling of Protease Specificity.Methods Mol Biol2017
26514758Current trends and challenges in proteomic identification of protease substrates.Biochimie2016
25626674Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S.Proteomics2015
26280490Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.J Med Chem2015
26081835Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells.Mol Cell Proteomics2015
24888522In vivo imaging of mouse tumors by a lipidated cathepsin S substrate.Angew Chem Int Ed Engl2014
24975267Selective targeting of tumor and stromal cells by a nanocarrier system displaying lipidated cathepsin B inhibitor.Angew Chem Int Ed Engl2014
25047918Human stefin B role in cell's response to misfolded proteins and autophagy.PLoS One2014
23362198Influence of partial unfolding and aggregation of human stefin B (cystatin B) EPM1 mutants G50E and Q71P on selective cleavages by cathepsins B and S.Biol Chem2013
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Collaborators

Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
Matthias Gstaiger
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
Andrea Fossati
J. David Gladstone Institutes
Co-authored papers 2
Federico Uliana
Institute of Biochemistry, ETH Zurich
Co-authored papers 2
Fabian Frommelt
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
Vito Turk
Jozef Stefan Institute
Co-authored papers 2
Eva Zerovnik
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Co-authored papers 2
Peter Kuhn
University of Tubingen
Co-authored papers 1
Stephan M Feller
Institute of Molecular Medicine, Martin-Luther-University of Halle-Wittenberg
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Rodolfo Ciuffa
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Ludovic Gillet
ETH Zurich
Co-authored papers 1
Vincenzo De Filippis
Department of Pharmaceutical and Pharmacological Sciences, University of Padua
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Bernd Wollscheid
ETH Zurich
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Ulrich Auf dem Keller
Technical University of Denmark
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Sandra Goetze
ETH Zurich
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Garth Powis
PHusis Therapeutics Inc.
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Laura Acquasaliente
Department of Pharmaceutical and Pharmacological Sciences, University of Padova
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Iztok Dolenc
J. Stefan Institute
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Marjana Novi??
National Institute of Chemistry
Co-authored papers 1
Ben C Collins
Queen's University of Belfast
Co-authored papers 1
Claudia Martelli
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
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