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Author Details

Jack F Greenblatt
College Street, University of Toronto
1969
251
95
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36597481Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors.Heliyon2023
37024975Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation.Epigenetics Chromatin2023
37323634Revised iCLIP-seq Protocol for Profiling RNA-protein Interaction Sites at Individual Nucleotide Resolution in Living Cells.Bio Protoc2023
37410772Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1.PLoS Pathog2023
37002329RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific.Sci Rep2023
36931259A central chaperone-like role for 14-3-3 proteins in human cells.Mol Cell2023
34782742A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.Nat Chem Biol2022
35863436The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1).J Biol Chem2022
35914530Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.Mol Cell2022
35914531Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1.Mol Cell2022
36114190A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.Nat Commun2022
34901782SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.iScience2022
34086947Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila.Nucleic Acids Res2021
34304093Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3.Virology2021
32460013MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.Cell Rep2020
31960028A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation.Nucleic Acids Res2020
32669707Nucleolar RNA polymerase II drives ribosome biogenesis.Nature2020
30420783Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity.Nat Microbiol2019
31653879Author Correction: Identification and Characterization of USP7 Targets in Cancer Cells.Sci Rep2019
31462557The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD.J Virol2019
31341047Identification of ARKL1 as a Negative Regulator of Epstein-Barr Virus Reactivation.J Virol2019
31280994The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation.Curr Biol2019
30804394USP7 Regulates Cytokinesis through FBXO38 and KIF20B.Sci Rep2019
31054975Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins.Mol Cell2019
30462309Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.Nucleic Acids Res2019
29176613Global landscape of cell envelope protein complexes in Escherichia coli.Nat Biotechnol2018
30367141Identification and Characterization of USP7 Targets in Cancer Cells.Sci Rep2018
29743367A Screen for Epstein-Barr Virus Proteins That Inhibit the DNA Damage Response Reveals a Novel Histone Binding Protein.J Virol2018
28157508Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors.Mol Cell2017
26700805SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination.Nature2016
27852650Multiparameter functional diversity of human C2H2 zinc finger proteins.Genome Res2016
27546533G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis.Stem Cell Reports2016
26976582Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.Proc Natl Acad Sci U S A2016
25316676Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in Escherichia coli.Bioinformatics2015
26437229Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.PLoS One2015
26344197Panorama of ancient metazoan macromolecular complexes.Nature2015
26870755Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes.Data Brief2015
26121405Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.Nat Methods2015
25690854C2H2 zinc finger proteins greatly expand the human regulatory lexicon.Nat Biotechnol2015
25782749Extracting high confidence protein interactions from affinity purification data: at the crossroads.J Proteomics2015
24170600A unified model for yeast transcript definition.Genome Res2014
24981860Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.Cell Rep2014
24997600RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.Nat Struct Mol Biol2014
24586182Quantitative genome-wide genetic interaction screens reveal global epistatic relationships of protein complexes in Escherichia coli.PLoS Genet2014
24565511Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function.Cell Rep2014
24454883The MoxR ATPase RavA and its cofactor ViaA interact with the NADH:ubiquinone oxidoreductase I in Escherichia coli.PLoS One2014
24501404Identification of herpesvirus proteins that contribute to G1/S arrest.J Virol2014
23292653Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.Nat Chem Biol2013
23831759Mapping the functional yeast ABC transporter interactome.Nat Chem Biol2013
23457193The carboxyl terminus of Rtt109 functions in chaperone control of histone acetylation.Eukaryot Cell2013
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Collaborators

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University of California San Francisco
Co-authored papers 53
University of Toronto, College Street
Co-authored papers 32
University of Toronto
Co-authored papers 24
University of Regina
Co-authored papers 20
College Street, University of Toronto
Co-authored papers 17
Toronto Metropolitan University
Co-authored papers 16
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Co-authored papers 15
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Co-authored papers 14
Harvard Medical School
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University of Regina
Co-authored papers 14
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Co-authored papers 13
VIB-VUB Center for Structural Biology
Co-authored papers 12
University of British Columbia
Co-authored papers 12
Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 12
University of Regina
Co-authored papers 11
EpiCypher Inc.
Co-authored papers 11
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Co-authored papers 11
Miguel Hernandez University of Elche.
Co-authored papers 11
University of Toronto
Co-authored papers 10
Canadian Arthritis Patient Alliance and Five02 Labs Inc.
Co-authored papers 10
Hospital for Sick Children
Co-authored papers 10
University of Toronto
Co-authored papers 10
The Hospital for Sick Children
Co-authored papers 10
University of Toronto
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Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
Co-authored papers 9
Beihang University
Co-authored papers 9
University of Regina
Co-authored papers 9
University of Toronto
Co-authored papers 8
McGill University
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