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Author Details

Alasdair C Steven
National Institutes of Health
1974
324
88
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35150605Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.Structure2022
33980829INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.Nat Commun2021
33727359Cryo-Electron Tomography of the Herpesvirus Procapsid Reveals Interactions of the Portal with the Scaffold and a Shift on Maturation.mBio2021
32286226Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss.Elife2020
31792961Capsids of hepatitis B virus e antigen with authentic C termini are stabilized by electrostatic interactions.FEBS Lett2020
33182609Biphasic Packing of DNA and Internal Proteins in Bacteriophage T4 Heads Revealed by Bubblegram Imaging.Viruses2020
32825132The Mottled Capsid of the <i>Salmonella</i> Giant Phage SPN3US, a Likely Maturation Intermediate with a Novel Internal Shell.Viruses2020
32310951Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae.PLoS Comput Biol2020
30541839Global Proteomic Profiling of <i>Salmonella</i> Infection by a Giant Phage.J Virol2019
30737287Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.Proc Natl Acad Sci U S A2019
30630865Cryo-EM of retinoschisin branched networks suggests an intercellular adhesive scaffold in the retina.J Cell Biol2019
29605570A new HIV-1 Rev structure optimizes interaction with target RNA (RRE) for nuclear export.J Struct Biol2018
30100358Structures of Hepatitis B Virus Core- and e-Antigen Immune Complexes Suggest Multi-point Inhibition.Structure2018
30021893The RNA-Binding Protein of a Double-Stranded RNA Virus Acts like a Scaffold Protein.J Virol2018
30017564Structure of an RNA Aptamer that Can Inhibit HIV-1 by Blocking Rev-Cognate RNA (RRE) Binding and Rev-Rev Association.Structure2018
30327442Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation.mBio2018
30555910A Computational Assay that Explores the Hemagglutinin/Neuraminidase Functional Balance Reveals the Neuraminidase Secondary Site as a Novel Anti-Influenza Target.ACS Cent Sci2018
29410085Journal of Structural Biology - Paper of the year 2017.J Struct Biol2018
28842495Chimeric rabbit/human Fab antibodies against the hepatitis Be-antigen and their potential applications in assays, characterization, and therapy.J Biol Chem2017
28611252The Primary Enveloped Virion of Herpes Simplex Virus 1: Its Role in Nuclear Egress.mBio2017
26984725Internal Proteins of the Procapsid and Mature Capsids of Herpes Simplex Virus 1 Mapped by Bubblegram Imaging.J Virol2016
26644467α-Synuclein Amyloid Fibrils with Two Entwined, Asymmetrically Associated Protofibrils.J Biol Chem2016
27507825Localization of the Houdinisome (Ejection Proteins) inside the Bacteriophage P22 Virion by Bubblegram Imaging.mBio2016
27265851The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly.Structure2016
27167730Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin.J Invest Dermatol2016
27114531Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina.Proc Natl Acad Sci U S A2016
25820430Distribution of DNA-condensing protein complexes in the adenovirus core.Nucleic Acids Res2015
26537676Identification of an HIV-1 Mutation in Spacer Peptide 1 That Stabilizes the Immature CA-SP1 Lattice.J Virol2015
26443463Subassemblies and asymmetry in assembly of herpes simplex virus procapsid.mBio2015
26178982Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation.J Virol2015
25958107Influenza virus-mediated membrane fusion: Structural insights from electron microscopy.Arch Biochem Biophys2015
24352457Mechanism of neutralization of herpes simplex virus by antibodies directed at the fusion domain of glycoprotein B.J Virol2014
25389177Metastable intermediates as stepping stones on the maturation pathways of viral capsids.mBio2014
25036632Structural basis of hAT transposon end recognition by Hermes, an octameric DNA transposase from Musca domestica.Cell2014
25029335Activated STING in a vascular and pulmonary syndrome.N Engl J Med2014
25024436A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress.EMBO J2014
25096873Maturation of the human papillomavirus 16 capsid.mBio2014
24853742Conformational switching in PolyGln amyloid fibrils resulting from a single amino acid insertion.Biophys J2014
24878961A cell-penetrating antibody fragment against HIV-1 Rev has high antiviral activity: characterization of the paratope.J Biol Chem2014
24715628Assessment of differences in the conformational flexibility of hepatitis B virus core-antigen and e-antigen by hydrogen deuterium exchange-mass spectrometry.Protein Sci2014
24345345Exploiting radiation damage to map proteins in nucleoprotein complexes: the internal structure of bacteriophage T7.J Struct Biol2014
24357008Sizing up large protein complexes by electrospray ionisation-based electrophoretic mobility and native mass spectrometry: morphology selective binding of Fabs to hepatitis B virus capsids.Anal Bioanal Chem2014
23079477Specificity of an anti-capsid antibody associated with Hepatitis B Virus-related acute liver failure.J Struct Biol2013
24109217A two-pronged structural analysis of retroviral maturation indicates that core formation proceeds by a disassembly-reassembly pathway rather than a displacive transition.J Virol2013
23891288Subunit folds and maturation pathway of a dsRNA virus capsid.Structure2013
23954653One number does not fit all: mapping local variations in resolution in cryo-EM reconstructions.J Struct Biol2013
23609437α-Synuclein oligomers with broken helical conformation form lipoprotein nanoparticles.J Biol Chem2013
23688956Clathrin-coated vesicles from brain have small payloads: a cryo-electron tomographic study.J Struct Biol2013
23597076Epitope-distal effects accompany the binding of two distinct antibodies to hepatitis B virus capsids.J Am Chem Soc2013
23776210MuB is an AAA+ ATPase that forms helical filaments to control target selection for DNA transposition.Proc Natl Acad Sci U S A2013
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Collaborators

J. B Heymann
Frederick National Laboratory for Cancer Research, Inc.
Co-authored papers 32
Wolfgang Baumeister
Max Planck Institute of Biochemistry
Co-authored papers 10
David A D Parry
Co-authored papers 8
Michael Unser
Ecole Polytechnique Federale de Lausanne (EPFL)
Co-authored papers 8
Albert J R Heck
Utrecht University
Co-authored papers 7
Rick K Huang
National Cancer Institute, National Institutes of Health
Co-authored papers 6
Phillip R Smith
Co-authored papers 6
Michael G Rossmann
Purdue University
Co-authored papers 6
David I Stuart
University of Oxford
Co-authored papers 4
Kay Gr??newald
Leibniz Institute of Virology
Co-authored papers 3
James H Hurley
University of California Berkeley
Co-authored papers 3
Hiro Tsuruta
Stanford University
Co-authored papers 2
John T Schiller
David Geffen School of Medicine at university of california los angeles
Co-authored papers 2
Ohad Medalia
University of Zurich
Co-authored papers 2
Kenji Iwasaki
Institute for Protein Research, Osaka University
Co-authored papers 2
Douglas R Lowy
Co-authored papers 2
Joachim Frank
Columbia University
Co-authored papers 2
Kelly K Lee
University of Washington
Co-authored papers 2
Edward H Egelman
University of Virginia
Co-authored papers 2
Susan T Weintraub
University of Texas Health Science Center at San Antonio Texas78229 USA.
Co-authored papers 2
Bridget Carragher
Columbia University
Co-authored papers 2
Ad Bax
National Institutes of Health
Co-authored papers 2
John A Hammer
National Heart Lung and Blood Institute, National Institutes of Health
Co-authored papers 1
Michael H Glickman
Technion-Israel Institute of Technology
Co-authored papers 1
Steven J Ludtke
Baylor College of Medicine
Co-authored papers 1
F W Studier
Brookhaven National Laboratory
Co-authored papers 1
Peter W Atkinson
University of California riverside
Co-authored papers 1
Wanxia Li Tsai
National Institute of Arthritis
Co-authored papers 1
Matthew L Baker
McGovern Medical School at the University of Texas Health Science Center
Co-authored papers 1
Xiaoqin Zou
Dalton Cardiovascular Research Center, University of Missouri
Co-authored papers 1
Release 1.2