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Author Details

Jens R Wendland
Takeda Pharmaceuticals USA
2000
62
33
PMIDPaper TitleJournal TitlePublished Year
36928351The D-amino acid oxidase inhibitor luvadaxistat improves mismatch negativity in patients with schizophrenia in a randomized trial.Neuropsychopharmacology2023
33990969Safety, pharmacokinetics and pharmacodynamics of TAK-418, a novel inhibitor of the epigenetic modulator lysine-specific demethylase 1A.Br J Clin Pharmacol2021
30622300Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression.Neuropsychopharmacology2019
31803055The Neuronal Glutamate Transporter EAAT3 in Obsessive-Compulsive Disorder.Front Pharmacol2019
30787427Correction: Behavioral and synaptic alterations relevant to obsessivecompulsive disorder in mice with increased EAAT3 expression.Neuropsychopharmacology2019
29596735Dennis Luke Murphy, M.D. (1936-2017).Genes Brain Behav2018
29930110Analysis of shared heritability in common disorders of the brain.Science2018
28159590Pharmacogenetics of antidepressant response: A polygenic approach.Prog Neuropsychopharmacol Biol Psychiatry2017
25778476A novel Alzheimer disease locus located near the gene encoding tau protein.Mol Psychiatry2016
27479909Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.Nat Genet2016
26211730An Integrative Genomic Study Implicates the Postsynaptic Density in the Pathogenesis of Bipolar Disorder.Neuropsychopharmacology2016
26140822Translating Neurogenomics Into New Medicines.Biol Psychiatry2016
25158072Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.Am J Psychiatry2015
24445990Copy number variants and therapeutic response to antidepressant medication in major depressive disorder.Pharmacogenomics J2014
25442931Translating human genetics into novel treatment targets for schizophrenia.Neuron2014
25327457Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes.Nat Commun2014
25062598Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.J Am Acad Child Adolesc Psychiatry2014
25093702Trio study and meta-analysis support the association of genetic variation at the serotonin transporter with early-onset obsessive-compulsive disorder.Neurosci Lett2014
24339138Genetic susceptibility for bipolar disorder and response to antidepressants in major depressive disorder.Am J Med Genet B Neuropsychiatr Genet2014
24393808RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.Mol Psychiatry2014
22182935Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.Mol Psychiatry2013
24204291Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.PLoS Genet2013
23606572Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1.Am J Med Genet B Neuropsychiatr Genet2013
23630162Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder.Mov Disord2013
23440468Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity.Philos Trans R Soc Lond B Biol Sci2013
23237317Contribution of common genetic variants to antidepressant response.Biol Psychiatry2013
23253771Age-modulated association between prefrontal NAA and the BDNF gene.Int J Neuropsychopharmacol2013
23321619Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes.Eur J Hum Genet2013
22889921Genome-wide association study of obsessive-compulsive disorder.Mol Psychiatry2013
22564678miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells.Int J Neuropsychopharmacol2013
21847142A systematic eQTL study of cis-trans epistasis in 210 HapMap individuals.Eur J Hum Genet2012
23091423Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.PLoS Med2012
19806148Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study.Mol Psychiatry2011
25236547Genetics of bipolar disorder.Curr Top Behav Neurosci2011
21668081Consideration of the BDNF gene in relation to two phenotypes: hoarding and obesity.J Abnorm Psychol2011
21473759Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice.BMC Pharmacol2011
21493958The genetics of panic disorder.J Med Genet2011
21185011Gene expression and genetic variation data implicate PCLO in bipolar disorder.Biol Psychiatry2011
20081856Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.Nat Genet2010
20519059Increased gene expression of diacylglycerol kinase η in bipolar disorder.Int J Neuropsychopharmacol2010
20643532The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: findings from a large German case-control and family-based sample.Schizophr Res2010
20213231Genetics of early-onset obsessive-compulsive disorder.Eur Child Adolesc Psychiatry2010
19927306A systematic association mapping on chromosome 6q in bipolar affective disorder--evidence for the melanin-concentrating-hormone-receptor-2 gene as a risk factor for bipolar affective disorder.Am J Med Genet B Neuropsychiatr Genet2010
20083391A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry.Schizophr Res2010
19096451Multiple rare SAPAP3 missense variants in trichotillomania and OCD.Mol Psychiatry2009
19765194Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation.J Neurochem2009
19349310A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder.Arch Gen Psychiatry2009
18077182Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling.Mol Cell Neurosci2008
18824000How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems.Neuropharmacology2008
18258298Leukemia inhibitory factor differentially regulates capsaicin and heat sensitivity in cultured rat dorsal root ganglion neurons.Neuropeptides2008
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Collaborators

Markus M N??then
Institute of Human Genetics, University Hospital Bonn
Co-authored papers 10
Francis J McMahon
National Institute of Mental Health, National Institutes of Health
Co-authored papers 10
Wolfgang Maier
University Hospital Bonn
Co-authored papers 10
Marcella Rietschel
Central Institute of Mental Health, University of Mannheim
Co-authored papers 9
James A Knowles
Co-authored papers 7
Thomas G Schulze
SUNY Upstate Medical University
Co-authored papers 7
Johannes Schumacher
Philipps University of Marburg
Co-authored papers 7
Benjamin D Greenberg
Warren Alpert School of Medicine, Brown University, Butler Hospital
Co-authored papers 6
Dongmei Yu
Co-authored papers 6
James L Kennedy
Institute of Medical Sciences, University of Toronto
Co-authored papers 6
Sven Cichon
University Hospital Basel and University of Basel
Co-authored papers 6
Michael A Jenike
Co-authored papers 6
Peter McGuffin
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Gregory L Hanna
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Co-authored papers 6
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Marion Leboyer
INSERM U
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Peter Heutink
German Center for Neurodegenerative Diseases (DZNE).
Co-authored papers 5
Danielle C Cath
Co-authored papers 5
Michele T Pato
Co-authored papers 5
Fabio Macciardi
Co-authored papers 5
Benjamin M Neale
Massachusetts General Hospital
Co-authored papers 5
Johannes H Smit
Co-authored papers 5
Danielle Posthuma
Co-authored papers 5
Carlos N Pato
Co-authored papers 5
Jay A Tischfield
Co-authored papers 5
Anne Farmer
Co-authored papers 5
Sara E Stewart
Co-authored papers 5
Release 1.2