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Author Details

Ronald Swanstrom
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
1972
250
72
Wade Schulz (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36791724Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection.Cell Rep Med2023
37662274<i>N</i><sup>4</sup> -Hydroxycytidine/Molnupiravir Inhibits RNA-Virus Induced Encephalitis by Producing Mutated Viruses with Reduced Fitness.bioRxiv2023
37283544Use of Next-Generation Sequencing in a State-Wide Strategy of HIV-1 Surveillance: Impact of the SARS-COV-2 Pandemic on HIV-1 Diagnosis and Transmission.J Infect Dis2023
37244161HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues.Eur J Med Chem2023
36920025Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance.Elife2023
36919694Nonsuppressible viremia during HIV-1 therapy meets molecular virology.J Clin Invest2023
36717718Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus.Nat Microbiol2023
36865569HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells.Pathog Immun2023
35975998Characterization of Macrophage-Tropic HIV-1 Infection of Central Nervous System Cells and the Influence of Inflammation.J Virol2022
35426377Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.J Clin Invest2022
35870649Encoded Conformational Dynamics of the HIV Splice Site A3 Regulatory Locus: Implications for Differential Binding of hnRNP Splicing Auxiliary Factors.J Mol Biol2022
36326446Unique Molecular Identifiers and Multiplexing Amplicons Maximize the Utility of Deep Sequencing To Critically Assess Population Diversity in RNA Viruses.ACS Infect Dis2022
32663847Near Real-Time Identification of Recent Human Immunodeficiency Virus Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by Multiplexed Primer ID-Next-Generation Sequencing in North Carolina.J Infect Dis2021
33796612Primer ID Next-Generation Sequencing for the Analysis of a Broad Spectrum Antiviral Induced Transition Mutations and Errors Rates in a Coronavirus Genome.Bio Protoc2021
33530363HIV-1: To Splice or Not to Splice, That Is the Question.Viruses2021
34835024Stephan Oroszlan and the Proteolytic Processing of Retroviral Proteins: Following A Pro.Viruses2021
33961695β-d-N4-hydroxycytidine Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells.J Infect Dis2021
34140354Epitranscriptomic addition of m<sup>6</sup>A regulates HIV-1 RNA stability and alternative splicing.Genes Dev2021
34255064Reply to Troth et al.J Infect Dis2021
31483374Female genital tract shedding of HIV-1 is rare in women with suppressed HIV-1 in plasma.AIDS2020
31914800HIV-1 Central Nervous System Compartmentalization and Cytokine Interplay in Non-Subtype B HIV-1 Infections in Nigeria and Malawi.AIDS Res Hum Retroviruses2020
33214714Author Correction: Determination of RNA structural diversity and its role in HIV-1 RNA splicing.Nature2020
32605062Multi-Laboratory Comparison of Next-Generation to Sanger-Based Sequencing for HIV-1 Drug Resistance Genotyping.Viruses2020
32796074Two Genetic Differences between Closely Related Zika Virus Strains Determine Pathogenic Outcome in Mice.J Virol2020
32759675Fact and Fiction about 1%: Next Generation Sequencing and the Detection of Minor Drug Resistant Variants in HIV-1 Populations with and without Unique Molecular Identifiers.Viruses2020
32672965Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere.J Med Chem2020
33021198The HIV-1 latent reservoir is largely sensitive to circulating T cells.Elife2020
32555469Determination of RNA structural diversity and its role in HIV-1 RNA splicing.Nature2020
32269129Deep Sequencing Reveals Compartmentalized HIV-1 in the Semen of Men with and without Sexually Transmitted Infection-Associated Urethritis.J Virol2020
32516949Next-Generation Sequencing for HIV Drug Resistance Testing: Laboratory, Clinical, and Implementation Considerations.Viruses2020
32533923Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.Cell Host Microbe2020
32253226An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.Sci Transl Med2020
32220311Curing HIV: Seeking to Target and Clear Persistent Infection.Cell2020
30561541Human Immunodeficiency Virus Type 1 RNA Detected in the Central Nervous System (CNS) After Years of Suppressive Antiretroviral Therapy Can Originate from a Replicating CNS Reservoir or Clonally Expanded Cells.Clin Infect Dis2019
31415754Epitranscriptomic Addition of m<sup>5</sup>C to HIV-1 Transcripts Regulates Viral Gene Expression.Cell Host Microbe2019
31413137Genome-Wide Analysis of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Binding to HIV-1 RNA Reveals a Key Role for hnRNP H1 in Alternative Viral mRNA Splicing.J Virol2019
31386368HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.J Med Chem2019
31597754The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation.Sci Transl Med2019
31507594Blocking Formation of the Stable HIV Reservoir: A New Perspective for HIV-1 Cure.Front Immunol2019
31361460Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.ACS Chem Biol2019
30814513Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies.Nat Commun2019
30675981Predicting Efavirenz Concentrations in the Brain Tissue of HIV-Infected Individuals and Exploring their Relationship to Neurocognitive Impairment.Clin Transl Sci2019
29708481Editorial: The HIV/SIV Envelope Protein: From Structure To Function To Host Evasion.Curr HIV Res2018
30081054Evolutionary pathways to NS5A inhibitor resistance in genotype 1 hepatitis C virus.Antiviral Res2018
30010965Using Primer-ID Deep Sequencing to Detect Recent Human Immunodeficiency Virus Type 1 Infection.J Infect Dis2018
30137025Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.J Clin Invest2018
30414407HIV-1 Protease Uses Bi-Specific S2/S2' Subsites to Optimize Cleavage of Two Classes of Target Sites.J Mol Biol2018
29756455Characterization of the Transmitted Virus in an Ongoing HIV-1 Epidemic Driven by Injecting Drug Use.AIDS Res Hum Retroviruses2018
29389021The evolution of HIV-1 entry phenotypes as a guide to changing target cells.J Leukoc Biol2018
29377940Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication.PLoS Pathog2018
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Collaborators

Shuntai Zhou
University of North Carolina at Chapel Hill
Co-authored papers 33
Joseph J Eron
Co-authored papers 22
David C Montefiori
Co-authored papers 17
Celia A Schiffer
University of Massachusetts Chan Medical School
Co-authored papers 16
Beatrice H Hahn
Co-authored papers 13
Barton F Haynes
Co-authored papers 11
Bette Korber
Co-authored papers 10
George M Shaw
Co-authored papers 10
Feng Gao
Co-authored papers 9
Jesus F Salazar-Gonzalez
Co-authored papers 8
Harold Varmus
Co-authored papers 8
Brandon F Keele
Co-authored papers 6
Ande West
University of North Carolina at Chapel Hill
Co-authored papers 5
Elena E Giorgi
Co-authored papers 5
Corbin D Jones
University of North Carolina at Chapel Hill
Co-authored papers 5
Roy M Gulick
Co-authored papers 5
Jeffrey A Frelinger
Co-authored papers 5
Richard Haubrich
Co-authored papers 5
Celia C LaBranche
Co-authored papers 5
Maria G Salazar
Co-authored papers 4
Akbar Ali
University of Massachusetts Chan Medical School
Co-authored papers 4
Ralph S Baric
University of North Carolina
Co-authored papers 4
Michael S Seaman
Co-authored papers 4
Paul D Bieniasz
The Rockefeller University
Co-authored papers 4
Prema Menezes
Co-authored papers 4
Kristen K Dang
Benaroya Research Institute at Virginia Mason
Co-authored papers 4
Benhur Lee
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Richard C Boucher
Co-authored papers 3
Julie M Decker
Co-authored papers 3
Daniel R Kuritzkes
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 3
Release 1.2