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Author Details

Keith A Johnson
Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School
1987
340
87
PMIDPaper TitleJournal TitlePublished Year
37728659Contribution of extracerebral tracer retention and partial volume effects to sex differences in Flortaucipir-PET signal.J Cereb Blood Flow Metab2024
37787849PET image denoising based on denoising diffusion probabilistic model.Eur J Nucl Med Mol Imaging2024
37932961Plasma Aβ42/Aβ40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.Alzheimers Dement2024
35298083Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease.Alzheimers Dement2023
37968130Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults.Neurology2023
37528163Cortical microstructural changes predict tau accumulation and episodic memory decline in older adults harboring amyloid.Commun Med (Lond)2023
37491329Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease.Neurology2023
37843849Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease.JAMA Neurol2023
38036535Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.Nat Commun2023
35862098Harmonizing the preclinical Alzheimer cognitive composite for multicohort studies.Neuropsychology2023
37458272Trial of Solanezumab in Preclinical Alzheimer's Disease.N Engl J Med2023
37291760Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease.Aging Cell2023
36950699Computerized cognitive practice effects in relation to amyloid and tau in preclinical Alzheimer's disease: Results from a multi-site cohort.Alzheimers Dement (Amst)2023
37188781Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man.Nat Med2023
37020050Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau.Mol Psychiatry2023
37212093Associations of the Harvard Automated Phone Task and Alzheimer's Disease Pathology in Cognitively Normal Older Adults: Preliminary Findings.J Alzheimers Dis2023
37116511Impact of motion correction on [<sup>18</sup>F]-MK6240 tau PET imaging.Phys Med Biol2023
37010830Association of Age at Menopause and Hormone Therapy Use With Tau and β-Amyloid Positron Emission Tomography.JAMA Neurol2023
37006330Preclinical Alzheimer's disease: how to predict who will decline next year?Brain Commun2023
37333223Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.medRxiv2023
36873926Development, initial validation, and application of a visual read method for [<sup>18</sup>F]MK-6240 tau PET.Alzheimers Dement (N Y)2023
36604327Correction to: Evaluation of pharmacokinetic modeling strategies for in-vivo quantification of tau with the radiotracer [<sup>18</sup>F]MK6240 in human subjects.Eur J Nucl Med Mol Imaging2023
36571821Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease.Alzheimers Dement2023
36420769Kinetic evaluation and assessment of longitudinal changes in reference region and extracerebral [<sup>18</sup>F]MK-6240 PET uptake.J Cereb Blood Flow Metab2023
36597122APOE effects on regional tau in preclinical Alzheimer's disease.Mol Neurodegener2023
35971310The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease.Alzheimers Dement2023
35962782Tau positron emission tomography in preclinical Alzheimer's disease.Brain2023
34160128Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults.Alzheimers Dement2022
35380901Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal-dominant Alzheimer's disease.Proc Natl Acad Sci U S A2022
35473760Association of β-Amyloid and Vascular Risk on Longitudinal Patterns of Brain Atrophy.Neurology2022
35471588Menopause Status Moderates Sex Differences in Tau Burden: A Framingham PET Study.Ann Neurol2022
35670654Progressive White Matter Injury in Preclinical Dutch Cerebral Amyloid Angiopathy.Ann Neurol2022
35821672Physical activity is associated with increased resting-state functional connectivity in networks predictive of cognitive decline in clinically unimpaired older adults.Alzheimers Dement (Amst)2022
35666520Association of Aortic Stiffness and Pressure Pulsatility With Global Amyloid-β and Regional Tau Burden Among Framingham Heart Study Participants Without Dementia.JAMA Neurol2022
35491781Blood Phosphorylated Tau 181 as a Biomarker for Amyloid Burden on Brain PET in Cognitively Healthy Adults.J Alzheimers Dis2022
35907254Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment.JAMA Neurol2022
35871328Association of Carotid Intima Media Thickening with Future Brain Region Specific Amyloid-β Burden.J Alzheimers Dis2022
35895837Network Tau spreading is vulnerable to the expression gradients of <i>APOE</i> and glutamatergic-related genes.Sci Transl Med2022
35880989Tau Mediates Synergistic Influence of Vascular Risk and Aβ on Cognitive Decline.Ann Neurol2022
35099509Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.JAMA Neurol2022
35095476Monthly At-Home Computerized Cognitive Testing to Detect Diminished Practice Effects in Preclinical Alzheimer's Disease.Front Aging Neurosci2022
35213372Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study.J Alzheimers Dis2022
35213373Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study.J Alzheimers Dis2022
35065037Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study.Lancet Neurol2022
35086372Effect of vascular amyloid on white matter disease is mediated by vascular dysfunction in cerebral amyloid angiopathy.J Cereb Blood Flow Metab2022
35173601Longitudinal Trajectories of Participant- and Study Partner-Rated Cognitive Decline, in Relation to Alzheimer's Disease Biomarkers and Mood Symptoms.Front Aging Neurosci2022
35338074Association of Emerging β-Amyloid and Tau Pathology With Early Cognitive Changes in Clinically Normal Older Adults.Neurology2022
35197359Associations of Stages of Objective Memory Impairment With Amyloid PET and Structural MRI: The A4 Study.Neurology2022
34958021Impact of 40â¿¿Hz Transcranial Alternating Current Stimulation on Cerebral Tau Burden in Patients with Alzheimer's Disease: A Case Series.J Alzheimers Dis2022
35322012Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals.Nat Commun2022
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Collaborators

Reisa A Sperling
Brigham and Women's Hospital, Massachusetts General Hospital
Co-authored papers 225
Gad A Marshall
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 62
Bernard Hanseeuw
Gordon Center for Medical Imaging, Massachusetts General Hospital
Co-authored papers 47
Jorge Sepulcre
Massachusetts General Hospital, the Gordon Center for Medical Imaging
Co-authored papers 34
Heidi I L Jacobs
Maastricht University
Co-authored papers 33
Joseph J Locascio
Harvard Medical School, Massachusetts General Hospital
Co-authored papers 30
Georges El Fakhri
Massachusetts General Hospital, the Gordon Center for Medical Imaging
Co-authored papers 29
Eric M Reiman
Banner Alzheimer's Institute
Co-authored papers 23
Rebecca A Betensky
New York University.
Co-authored papers 18
Hyun-Sik Yang
Massachusetts General Hospital, the Gordon Center for Medical Imaging
Co-authored papers 18
John C Morris
Washington University School of Medicine
Co-authored papers 17
Bradley T Hyman
Massachusetts General Hospital
Co-authored papers 17
Steven M Greenberg
Massachusetts General Hospital
Co-authored papers 16
Marc D Normandin
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Co-authored papers 15
Clifford R Jack
Mayo Clinic Rochester
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Julie C Price
Massachusetts General Hospital
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Matthew P Frosch
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 14
Anand Viswanathan
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 14
Stephen Salloway
Butler Hospital, and Warren Alpert Medical School of Brown University
Co-authored papers 13
Nick C Fox
UK Dementia Research Institute, University College London
Co-authored papers 13
Paul S Aisen
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 13
Michael C Donohue
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 12
Quanzheng Li
Massachusetts General Hospital
Co-authored papers 11
Eric McDade
Washington University St. Louis
Co-authored papers 11
Kewei Chen
Beijing Normal University
Co-authored papers 11
Peter R Schofield
University of New South Wales
Co-authored papers 11
Andrew J Saykin
Indiana University School of Medicine
Co-authored papers 10
Federico d'Oleire Uquillas
Princeton Neuroscience Institute, Princeton University
Co-authored papers 10
Robert A Koeppe
University of Michigan ann arbor
Co-authored papers 10
Mark A Mintun
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Release 1.2