Author details

Full Name

Scott R Burrows

Affiliation

ORCID

Career Start Year

1983

Papers

177

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34705104	Estimating the global burden of Epstein-Barr virus-related cancers.	Journal of Cancer Research and Clinical Oncology	2022
33055421	Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis.	JCI insight	2020
30770409	The early proximal Î±Î² TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network.	Science immunology	2019
32704085	Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells.	Gene Ther	2019
29528337	Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.	Journal of Clinical Investigation	2018
30429369	Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis.	JCI insight	2018
27670790	CD8 T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.	Immunology and Cell Biology	2017
28748090	Erratum: Defective T-cell control of Epstein-Barr virus infection in multiple sclerosis.	Clinical and Translational Immunology	2017
28197337	Defective T-cell control of Epstein-Barr virus infection in multiple sclerosis.	Clinical and Translational Immunology	2017
27748447	Targeted suppression of autoreactive CD8 T-cell activation using blocking anti-CD8 antibodies.	Scientific Reports	2016
26846725	Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors.	Immunology and Cell Biology	2016
27279616	Coinfection with Human Cytomegalovirus Genetic Variants in Transplant Recipients and Its Impact on Antiviral T Cell Immune Reconstitution.	Journal of Virology	2016
27307560	Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells.	J Immunol	2016
26422112	The impact of HLA class I and EBV latency-II antigen-specific CD8(+) T cells on the pathogenesis of EBV(+) Hodgkin lymphoma.	Clinical and Experimental Immunology	2016
26321144	A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy.	Stem Cell Reports	2015
25801351	Naive CD8âº T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics.	Immunology and Cell Biology	2015
25355876	T cell epitope clustering in the highly immunogenic BZLF1 antigen of Epstein-Barr virus.	Journal of Virology	2015
25855358	T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells.	J Immunol	2015
24646048	Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire.	British Journal of Haematology	2014
25505955	Epstein-Barr virus and multiple sclerosis: potential opportunities for immunotherapy.	Clinical and Translational Immunology	2014
24493474	Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis.	Multiple Sclerosis Journal	2014
24550917	Multivariate Analysis Using High Definition Flow Cytometry Reveals Distinct T Cell Repertoires between the Fetal-Maternal Interface and the Peripheral Blood.	Frontiers in Immunology	2014
24854165	CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria.	PLoS Pathog	2014
24759101	A molecular basis for the interplay between T cells, viral mutants, and human leukocyte antigen micropolymorphism.	J Biol Chem	2014
24893674	EBV & HHV6 reactivation is infrequent and not associated with MS clinical course.	Acta Neurologica Scandinavica	2014
24842963	Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis.	Multiple Sclerosis Journal	2014
24509977	Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.	Scientific Reports	2014
23569211	Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule.	J Biol Chem	2013
23995877	IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling.	Nature Communications	2013
23935599	Immune parameters to consider when choosing T-cell receptors for therapy.	Frontiers in Immunology	2013
23749632	HLA peptide length preferences control CD8+ T cell responses.	J Immunol	2013
23255554	Peptide length determines the outcome of TCR/peptide-MHCI engagement.	Blood	2013
23077319	High frequency of herpesvirus-specific clonotypes in the human T cell repertoire can remain stable over decades with minimal turnover.	Journal of Virology	2013
22013037	Epstein-Barr virus isolates retain their capacity to evade T cell immunity through BNLF2a despite extensive sequence variation.	Journal of Virology	2012
22343629	The energetic basis underpinning T-cell receptor recognition of a super-bulged peptide bound to a major histocompatibility complex class I molecule.	J Biol Chem	2012
22924682	Tracking the repertoire of human adult and neonatal T cells during ex vivo amplification.	British Journal of Haematology	2012
22722860	Immune self-reactivity triggered by drug-modified HLA-peptide repertoire.	Nature	2012
22323539	The impact of a large and frequent deletion in the human TCR Î² locus on antiviral immunity.	Journal of Immunology	2012
22942184	Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells.	Blood	2012
23046123	A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned.	Immunological Reviews	2012
23243157	CD8+ T cells far predominate over CD4+ T cells in healthy immune response to Epstein-Barr virus infected lymphoblastoid cell lines.	Blood	2012
21791511	CD8 T cell deficiency impairs control of Epstein--Barr virus and worsens with age in multiple sclerosis.	Journal of Neurology, Neurosurgery and Psychiatry	2012
22140258	A structural basis for varied Î±Î² TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.	J Immunol	2012
21753179	Current and past Epstein-Barr virus infection in risk of initial CNS demyelination.	Neurology	2011
21301481	Understanding human T-cell-mediated immunoregulation through herpesviruses.	Immunology and Cell Biology	2011
21160049	Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection.	Journal of Immunology	2011
21412238	Human immunology: a case for the ascent of non-furry immunology.	Immunology and Cell Biology	2011
21810280	Decreased CD8+ T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes.	BMC Neurology	2011
21677135	Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.	Journal of Immunology	2011
20190139	MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.	Journal of Immunology	2010