Author details

Full Name

Kerrin S Small

Affiliation

ORCID

Career Start Year

2007

Papers

113

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37503126	Understanding the genetic complexity of puberty timing across the allele frequency spectrum.	medRxiv	2023
37620324	Analysis of subcellular RNA fractions demonstrates significant genetic regulation of gene expression in human brain post-transcriptionally.	Sci Rep	2023
37961277	Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.	bioRxiv	2023
37858220	Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome.	Clin Epigenetics	2023
36802379	Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable.		2023
37053313	The origins and functional effects of postzygotic mutations throughout the human life span.	Science	2023
36458982	PPI-Induced Changes in Plasma Metabolite Levels Influence Total Hip Bone Mineral Density in a UK Cohort.	J Bone Miner Res	2023
34875679	Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.	Journal of Clinical Endocrinology and Metabolism	2022
35843982	Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers.	Genome Med	2022
35589964	ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.	Int J Obes (Lond)	2022
36064109	Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice.	Molecular Metabolism	2022
36412098	Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans.	Elife	2022
33402392	Current smoking and COVID-19 risk: results from a population symptom app in over 2.4 million people.	Thorax	2021
33593402	Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects.	Clin Epigenetics	2021
33479282	Further evidence supporting a potential role for ADH1B in obesity.	Sci Rep	2021
34108472	Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.	Nat Commun	2021
32986799	Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults.	Age Ageing	2021
32913075	Cell type-specific genetic regulation of gene expression across human tissues.	Science	2020
31697828	Concordance for clonal hematopoiesis is limited in elderly twins.	Blood	2020
32493999	RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro.	Nat Commun	2020
33311586	Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract.	Commun Biol	2020
32817962	ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition.	medRxiv	2020
32759275	Estrogen receptor Î± controls metabolism in white and brown adipocytes by regulating <i>Polg1</i> and mitochondrial remodeling.	Sci Transl Med	2020
32701509	X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity.	J Clin Invest	2020
30775970	Nuclear genetic regulation of the human mitochondrial transcriptome.	eLife	2019
31767861	Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age.	Nat Commun	2019
31092820	Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus.	Nature Communications	2019
31526404	TwinsUK: The UK Adult Twin Registry Update.	Twin Res Hum Genet	2019
30760334	Epigenetic findings in periodontitis in UK twins: a cross-sectional study.	Clin Epigenetics	2019
31130283	Cell-Type Heterogeneity in Adipose Tissue Is Associated with Complex Traits and Reveals Disease-Relevant Cell-Specific eQTLs.	American Journal of Human Genetics	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
31118516	Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.	Nature	2019
29808030	The fecal metabolome as a functional readout of the gut microbiome.	Nat Genet	2018
30342560	Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health.	Clin Epigenetics	2018
30193568	Fasting and time of day independently modulate circadian rhythm relevant gene expression in adipose and skin tissue.	BMC Genomics	2018
30135520	Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.	Nat Commun	2018
30087441	Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.	Nat Genet	2018
29228364	Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort.	Hum Mol Genet	2018
29666371	Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.	Nat Commun	2018
29549330	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29549329	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
29632379	Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.	Nat Genet	2018
29360107	Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2018
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
28302734	Time-dependent genetic effects on gene expression implicate aging processes.	Genome Res	2017
28552196	Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.	Am J Hum Genet	2017
28341696	A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.	Diabetes	2017
28883458	Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood.	Nat Commun	2017
29058714	Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues.	Nat Genet	2017