Author details

Full Name

John D Rioux

Affiliation

ORCID

Career Start Year

1988

Papers

214

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37976264	Clinical Predictors of Early and Late Endoscopic Recurrence Following Ileocolonic Resection in Crohn's Disease.	J Crohns Colitis	2024
36527757	Identifying transcript-level differential expression in primary human immune cells.		2023
38077122	Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.		2023
37080976	Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients.	Nat Commun	2023
37080587	Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.	Gut	2023
37446397	Investigating the Crime Scene-Molecular Signatures in Inflammatory Bowel Disease.		2023
36993181	Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.		2023
36662167	Serum Lipidomic Screen Identifies Key Metabolites, Pathways, and Disease Classifiers in Crohn's Disease.	Inflamm Bowel Dis	2023
34698823	A Role for CXCR3 Ligands as Biomarkers of Post-Operative Crohn's Disease Recurrence.	J Crohns Colitis	2022
35394816	Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation.	Sci Immunol	2022
36038634	Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.	Nat Genet	2022
35952671	Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.	Cell	2022
36155972	Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases.	PLoS Genetics	2022
35218908	IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation.	Cellular Signalling	2022
34758847	Functional screen of inflammatory bowel disease genes reveals key epithelial functions.	Genome Med	2021
33600772	Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease.	Am J Hum Genet	2021
33555323	Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations.	Hum Mol Genet	2021
33367594	Life-threatening arrhythmias with autosomal recessive TECRL variants.	Europace	2021
33359885	Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort.	Gastroenterology	2021
33421512	Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target.	Gastroenterology	2021
32869539	A genetic association study of heart failure: more evidence for the role of BAG3 in idiopathic dilated cardiomyopathy.	ESC Heart Fail	2020
32469933	A transcriptome-based approach to identify functional modules within and across primary human immune cells.	PLoS ONE	2020
33087380	IMAGINE Network's ind nd ut nteractions ohort (MAGIC) Study: a protocol for a prospective observational multicentre cohort study in inflammatory bowel disease and irritable bowel syndrome.	BMJ Open	2020
31145742	Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.	PLoS Genet	2019
31554740	alleles modulate inflammation during microbial infection of mice in a sex-dependent manner.	Science Translational Medicine	2019
30760205	Inflammatory bowel disease patient perceptions of diagnostic and monitoring tests and procedures.	BMC Gastroenterology	2019
30850479	Innate Control of Tissue-Reparative Human Regulatory T Cells.	J Immunol	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
31158699	Induced and spontaneous colitis mouse models reveal complex interactions between IL-10 and IL-12/IL-23 pathways.	Cytokine	2019
31341105	Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder.	JCI insight	2019
29795570	Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.	PLoS Genet	2018
28760459	Patients' perception of their involvement in shared treatment decision making: Key factors in the treatment of inflammatory bowel disease.	Patient Education and Counseling	2018
30169657	A comprehensive evaluation of the genetic architecture of sudden cardiac arrest.	Eur Heart J	2018
30256116	Comprehensive and Reproducible Untargeted Lipidomic Workflow Using LC-QTOF Validated for Human Plasma Analysis.	J Proteome Res	2018
29549330	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29549329	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29420262	<i>C1orf106</i> is a colitis risk gene that regulates stability of epithelial adherens junctions.	Science	2018
29321258	Functional variants in the <i>LRRK2</i> gene confer shared effects on risk for Crohn's disease and Parkinson's disease.	Sci Transl Med	2018
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
28146470	Rare and low-frequency coding variants alter human adult height.	Nature	2017
28506689	Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.	Gastroenterology	2017
28767105	Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.	Nat Commun	2017
28813717	Exploring the Use of a Participative Design in the Early Development of a Predictive Test: The Importance of Physician Involvement.	Public Health Genomics	2017
28714469	Transancestral mapping and genetic load in systemic lupus erythematosus.	Nat Commun	2017
28575497	Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion.	Hum Mol Genet	2017
28658209	Fine-mapping inflammatory bowel disease loci to single-variant resolution.	Nature	2017
28613276	Genetic loci associated with heart rate variability and their effects on cardiac disease risk.	Nat Commun	2017
29053992	Biomarker-guided stratification of autoimmune patients for biologic therapy.		2017
29021306	Characterization of a Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for the Study of Variant Pathogenicity: Validation of a Mutation.	Circulation: Cardiovascular Genetics	2017
29083408	Exome-wide association study of plasma lipids in >300,000 individuals.	Nat Genet	2017