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Author Details

Takashi Shingu
The University of Texas MD Anderson Cancer Center
1979
36
14
PMIDPaper TitleJournal TitlePublished Year
36705543Novel murine glioblastoma models that reflect the immunotherapy resistance profile of a human disease.Neuro Oncol2023
36051438Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma.Front Cell Dev Biol2022
33045062Qki is an essential regulator of microglial phagocytosis in demyelination.J Exp Med2021
33745946Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer.Gastroenterology2021
34021134Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency.Nat Commun2021
33942715Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis.Elife2021
32202512Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism.J Clin Invest2020
27841882Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.Nat Genet2017
26880988Glioma Stem Cells: Signaling, Microenvironment, and Therapy.Stem Cells Int2016
26861698Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.J Transl Med2016
25938254Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.J Vis Exp2015
20473884Combined action of the dinuclear platinum compound BBR3610 with the PI3-K inhibitor PX-866 in glioblastoma.Int J Cancer2011
21795717Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis.J Biol Chem2011
20713409The polynuclear platinum BBR3610 induces G2/M arrest and autophagy early and apoptosis late in glioma cells.Neuro Oncol2010
19048625Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells.Int J Cancer2009
19270491Stage-specific effect of inhibition of autophagy on chemotherapy-induced cytotoxicity.Autophagy2009
18259115Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.Autophagy2008
17527050Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report.Neurol Med Chir (Tokyo)2007
16247240Supratentorial primitive neuroectodermal tumor in an aged patient--case report--.Neurol Med Chir (Tokyo)2005
12546364Growth inhibition of human malignant glioma cells induced by the PI3-K-specific inhibitor.J Neurosurg2003
12874004Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.Cancer Res2003
12854763A new, miniature ultrasonic surgical aspirator with a handpiece designed for transsphenoidal surgery. Technical note.J Neurosurg2003
12005398Experimental validation of deuterium oxide-mediated antitumoral activity as it relates to apoptosis in murine malignant astrocytoma cells.J Neurosurg2002
9430148[A case of pituitary apoplexy: remarkable improvement of visual acuity and field by surgical intervention at the subchronic stage].No Shinkei Geka1997
7700497[Non-traumatic cerebrospinal fluid rhinorrhea associated with hydrocephalus: a case report].No Shinkei Geka1995
7786628[A case of deep sylvian meningioma presenting temporal lobe epilepsy].No To Shinkei1995
7609832[Primary oculomotor nerve palsy due to head injury: analysis of 10 cases].No Shinkei Geka1995
7514750Spontaneous subperiosteal hematoma of the orbit--case report.Neurol Med Chir (Tokyo)1994
8133963[Dilated pericerebellar fluid space in patients with chronic subdural hematoma].No Shinkei Geka1994
7816180[Traumatic anterior cerebral artery aneurysm difficult to distinguish from congenital cerebral aneurysm: case report].No Shinkei Geka1994
2398394Meningioma with hypergammaglobulinemia. Case report.J Neurosurg1990
2984632Evaluation of a low dose administration of aspirin, dipyridamol and steroid. Therapeutic effects on motor function and protective effects on Na+-K+-activated ATPase activity against lipid peroxidation in an experimental model of spinal cord injury.Paraplegia1985
4022250[Regional continuous intraarterial infusion of urokinase in the acute stage of cervical and intracranial major artery occlusion--particularly on a case of successful improvement after therapeutic recanalization].No Shinkei Geka1985
6664453[Brain abscess: successful treatment of 4 cases including one with ventricular perforation].No Shinkei Geka1983
6153765[Noxious free radicals derived from oxyhemoglobin as a cause of prolonged vasospasm].Neurol Med Chir (Tokyo)1980
93246[99m Tc scan dynamics in cerebral infarcted area--as an indicator of vascular reconstruction (author's transl)].Neurol Med Chir (Tokyo)1979
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Collaborators

Shimane University School of Medicine
Co-authored papers 8
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 6
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Co-authored papers 5
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences
Co-authored papers 5
Shimane University Hospital
Co-authored papers 4
Northwestern University Feinberg School of Medicine
Co-authored papers 4
Kumamoto University Hospital
Co-authored papers 3
Jyoban Hospital, Tokiwa Foundation
Co-authored papers 3
Center for Global Health, School of Public Health, Nanjing Medical University
Co-authored papers 3
Kohsei Chuo General Hospital.
Co-authored papers 3
Virginia Commonwealth University, United States of America Massey Cancer Center
Co-authored papers 3
University of Texas M.D. Anderson Cancer Center
Co-authored papers 3
Moffitt Cancer Center
Co-authored papers 2
National Cancer Center
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
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Co-authored papers 1
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Yale School of Medicine
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PHusis Therapeutics Inc.
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MD Anderson Cancer Center
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The University of Texas M.D. Anderson Cancer Center
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The University of Texas MD Anderson Cancer Center
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The University of MD Anderson Cancer Center
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Tokyo University of Science
Co-authored papers 1