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Author Details

Philip T F Williamson
University of Southampton
1997
50
20
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36932824Lipophilicity Modulations by Fluorination Correlate with Membrane Partitioning.Angew Chem Int Ed Engl2023
37686007The Stabilization of S100A9 Structure by Calcium Inhibits the Formation of Amyloid Fibrils.Int J Mol Sci2023
37330283Impact on S. aureus and E. coli Membranes of Treatment with Chlorhexidine and Alcohol Solutions: Insights from Molecular Simulations and Nuclear Magnetic Resonance.J Mol Biol2023
36388517Integrated analysis reveals effects of bioactive ingredients from <i>Limonium Sinense</i> (Girard) Kuntze on hypoxia-inducible factor (HIF) activation.Front Plant Sci2022
32321274Optimization and validation of a deep learning CuZr atomistic potential: Robust applications for crystalline and amorphous phases with near-DFT accuracy.J Chem Phys2020
32827182Strategies for <sup>1</sup> H-Detected Dynamic Nuclear Polarization Magic-Angle Spinning NMR Spectroscopy.Chemistry2020
32417184Magnetically aligned membrane mimetics enabling comparable chiroptical and magnetic resonance spectroscopy studies.Biochim Biophys Acta Biomembr2020
30481605<sup>14</sup>N overtone NMR under MAS: Signal enhancement using cross-polarization methods.J Magn Reson2019
30809601Quantitative analysis of <sup>14</sup>N quadrupolar coupling using <sup>1</sup>H detected <sup>14</sup>N solid-state NMR.Phys Chem Chem Phys2019
28710349Lipid Driven Nanodomains in Giant Lipid Vesicles are Fluid and Disordered.Sci Rep2017
28314880Comparative study of the structure and interaction of the pore helices of the hERG and Kv1.5 potassium channels in model membranes.Eur Biophys J2017
29072716Measurement of <sup>14</sup>N quadrupole couplings in biomolecular solids using indirect-detection <sup>14</sup>N solid-state NMR with DNP.Chem Commun (Camb)2017
29242346Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers.Science2017
29116557Bidirectional band-selective magnetization transfer along the protein backbone doubles the information content of solid-state NMR correlation experiments.J Biomol NMR2017
28750163Salt Gradient Modulation of MicroRNA Translocation through a Biological Nanopore.Anal Chem2017
28863821Relevance of CARC and CRAC Cholesterol-Recognition Motifs in the Nicotinic Acetylcholine Receptor and Other Membrane-Bound Receptors.Curr Top Membr2017
26866469C60 fullerene localization and membrane interactions in RAW 264.7 immortalized mouse macrophages.Nanoscale2016
27951690Magnetically Oriented Bicelles with Monoalkylphosphocholines: Versatile Membrane Mimetics for Nuclear Magnetic Resonance Applications.Langmuir2016
26915987A mirror code for protein-cholesterol interactions in the two leaflets of biological membranes.Sci Rep2016
25662410(14)N overtone NMR under MAS: signal enhancement using symmetry-based sequences and novel simulation strategies.Phys Chem Chem Phys2015
26299667(14)N overtone transition in double rotation solid-state NMR.Phys Chem Chem Phys2015
25944559Interaction between the NS4B amphipathic helix, AH2, and charged lipid headgroups alters membrane morphology and AH2 oligomeric state--Implications for the Hepatitis C virus life cycle.Biochim Biophys Acta2015
24797658Lipid concentration and molar ratio boundaries for the use of isotropic bicelles.Langmuir2014
23589073An efficient NMR method for the characterisation of 14N sites through indirect 13C detection.Phys Chem Chem Phys2013
24162163Single-channel electrophysiology of cell-free expressed ion channels by direct incorporation in lipid bilayers.Analyst2013
21963409Probing the interaction of lipids with the non-annular binding sites of the potassium channel KcsA by magic-angle spinning NMR.Biochim Biophys Acta2012
22955930In support of the BMRB.Nat Struct Mol Biol2012
22075563Probing the oligomeric state and interaction surfaces of Fukutin-I in dilauroylphosphatidylcholine bilayers.Eur Biophys J2012
22238149Morphological differences between β(2) -microglobulin in fibrils and inclusion bodies.Chembiochem2011
20117215Expression and purification of the transmembrane domain of Fukutin-I for biophysical studies.Protein Expr Purif2010
21105749Stability and membrane orientation of the fukutin transmembrane domain: a combined multiscale molecular dynamics and circular dichroism study.Biochemistry2010
18390599Dynamics and Cleavability at the alpha-cleavage site of APP(684-726) in different lipid environments.Biophys J2008
17989232The conformation of acetylcholine at its target site in the membrane-embedded nicotinic acetylcholine receptor.Proc Natl Acad Sci U S A2007
16390143Orientation and conformational preference of leucine-enkephalin at the surface of a hydrated dimyristoylphosphatidylcholine bilayer: NMR and MD simulation.J Am Chem Soc2006
15869282Molecular insight into the electrostatic membrane surface potential by 14n/31p MAS NMR spectroscopy: nociceptin-lipid association.J Am Chem Soc2005
16373320Structural and dynamic studies of the gamma-M4 trans-membrane domain of the nicotinic acetylcholine receptor.Mol Membr Biol2005
15132669NMR characterization of native liquid spider dragline silk from Nephila edulis.Biomacromolecules2004
14740198Structural and functional studies of the nicotinic acetylcholine receptor by solid-state NMR.Eur Biophys J2004
15140443Rotational-resonance distance measurements in multi-spin systems.J Magn Reson2004
12603160Determination of internuclear distances in uniformly labeled molecules by rotational-resonance solid-state NMR.J Am Chem Soc2003
12652121Switched-angle spinning applied to bicelles containing phospholipid-associated peptides.J Biomol NMR2003
12652120NMR of bicelles: orientation and mosaic spread of the liquid-crystal director under sample rotation.J Biomol NMR2003
11997028Probing the environment of neurotensin whilst bound to the neurotensin receptor by solid state NMR.FEBS Lett2002
11226242Dynamics and orientation of N+(CD3)3-bromoacetylcholine bound to its binding site on the nicotinic acetylcholine receptor.Proc Natl Acad Sci U S A2001
10873541Expression and purification of recombinant neurotensin in Escherichia coli.Protein Expr Purif2000
10467737Membrane protein structure determination by solid state NMR.Nat Prod Rep1999
10460174Binding properties of the stilbene disulfonate sites on human erythrocyte AE1: kinetic, thermodynamic, and solid state deuterium NMR analyses.Biochemistry1999
9766016Solid state NMR studies of ligands bound to the nicotinic acetylcholine receptor.Biochem Soc Trans1998
9692976Probing the agonist binding pocket in the nicotinic acetylcholine receptor: a high-resolution solid-state NMR approach.Biochemistry1998
9398355Macroscopic orientation of natural and model membranes for structural studies.Anal Biochem1997
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Collaborators

Anthony Watts
Oxford University
Co-authored papers 12
Aswin Verhoeven
Leiden University Medical Center, Center for Proteomics & Metabolomics
Co-authored papers 3
Michele Vendruscolo
University of Cambridge
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Walter J Chazin
and Center for Structural Biology, Vanderbilt University
Co-authored papers 1
Bernd Reif
Technische Universitat Munchen (TUM)
Co-authored papers 1
Matthew P Crump
University of Bristol
Co-authored papers 1
Alexander P Golovanov
The University of Manchester
Co-authored papers 1
David A Case
Rutgers University
Co-authored papers 1
Oliver F Lange
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
Gordon C K Roberts
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 1
Josep Rizo
University of Texas Southwestern Medical Center
Co-authored papers 1
Mike P Williamson
The University of Sheffield
Co-authored papers 1
Lu-Yun Lian
Institute of Systems, The University of Liverpool
Co-authored papers 1
Igor L Barsukov
Institute of Integrative Biology, University of Liverpool
Co-authored papers 1
David E Shaw
Columbia University
Co-authored papers 1
Ad Bax
National Institutes of Health
Co-authored papers 1
Patrick C A van der Wel
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
David Middleton
Co-authored papers 1
Ioannis Vakonakis
University of Oxford
Co-authored papers 1
Thomas A Frenkiel
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
Ernest D Laue
University of Cambridge
Co-authored papers 1
Gordon S Rule
Carnegie Mellon University
Co-authored papers 1
Stephen Matthews
Imperial College London
Co-authored papers 1
Chien Ho
Carnegie Mellon University
Co-authored papers 1
Toshimichi Fujiwara
Institute for Protein Research, Osaka University
Co-authored papers 1
Pei Tang
Sichuan University
Co-authored papers 1
Joern Werner
Co-authored papers 1
Paul C Driscoll
The Francis Crick Institute
Co-authored papers 1
Shigeyuki Yokoyama
Shinshu University School of Medicine
Co-authored papers 1
Release 1.2