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Author Details

Rengul Cetin-Atalay
Middle East Technical University
1994
100
25
PMIDPaper TitleJournal TitlePublished Year
36826944Human Hepatocellular Carcinoma Classification from H&E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function.J Imaging2023
37387156Transfer learning for drug-target interaction prediction.Bioinformatics2023
37234266Novel Indole-Pyrazole Hybrids as Potential Tubulin-Targeting Agents; Synthesis, antiproliferative evaluation, and molecular modeling studies.J Mol Struct2023
34165413Design, Synthesis and Biological Evaluation of Novel Triazolothiadiazoles Derived from NSAIDs as Anticancer Agents.Anticancer Agents Med Chem2022
35801913SLPred: a multi-view subcellular localization prediction tool for multi-location human proteins.Bioinformatics2022
35822617HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury.Elife2022
36278052Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with <i>In Vitro</i> Growth Inhibitory and <i>In Vivo</i> Antitumor Activity.ACS Omega2022
36071119A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation.Sci Rep2022
36229484Intermittent hypoxia inhibits epinephrine-induced transcriptional changes in human aortic endothelial cells.Sci Rep2022
35331184Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells.BMC Cancer2022
34718348EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers.Oncogene2022
33067636MDeePred: novel multi-channel protein featurization for deep learning-based binding affinity prediction in drug discovery.Bioinformatics2021
33907497Transcriptome profiles associated with selenium-deficiency-dependent oxidative stress identify potential diagnostic and therapeutic targets in liver cancer cells.Turk J Biol2021
33713038Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation.Chem Biodivers2021
34910274Data Centric Molecular Analysis and Evaluation of Hepatocellular Carcinoma Therapeutics Using Machine Intelligence-Based Tools.J Gastrointest Cancer2021
34930409Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines.BMC Chem2021
34961772Identification of an mRNA isoform switch for HNRNPA1 in breast cancers.Sci Rep2021
34843456Protein domain-based prediction of drug/compound-target interactions and experimental validation on LIM kinases.PLoS Comput Biol2021
34181736CROssBAR: comprehensive resource of biomedical relations with knowledge graph representations.Nucleic Acids Res2021
34322038Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated <i>via</i> Sympathetic Activation-Dependent Catecholamine Release.Front Physiol2021
33951549Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells.Eur J Med Chem2021
32438298DeepDistance: A multi-task deep regression model for cell detection in inverted microscopy images.Med Image Anal2020
33558921Design, Synthesis and In Vitro Cytotoxic Activity of New 6,9-Disubstituted Purine Analogues.Acta Chim Slov2020
31818629Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening.Bioorg Med Chem2020
33094316iBioProVis: interactive visualization and analysis of compound bioactivity space.Bioinformatics2020
32678233A small library of chalcones induce liver cancer cell death through Akt phosphorylation inhibition.Sci Rep2020
32668192TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation.Am J Respir Cell Mol Biol2020
32249801CXXC5 as an unmethylated CpG dinucleotide binding protein contributes to estrogen-mediated cellular proliferation.Sci Rep2020
32546710Author Correction: CXXC5 as an unmethylated CpG dinucleotide binding protein contributes to estrogen-mediated cellular proliferation.Sci Rep2020
30579980Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine-(thio)urea hybrids as potential kinase inhibitors.Comput Biol Chem2019
31744546The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.Genome Biol2019
30084866Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases.Brief Bioinform2019
31439713Targeting PI3K/Akt/mTOR Pathway Identifies Differential Expression and Functional Role of IL8 in Liver Cancer Stem Cell Enrichment.Mol Cancer Ther2019
30870650Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors.J Mol Graph Model2019
31089211DEEPred: Automated Protein Function Prediction with Multi-task Feed-forward Deep Neural Networks.Sci Rep2019
30716712Synthesis of new derivatives of boehmeriasin A and their biological evaluation in liver cancer.Eur J Med Chem2019
29350768Diet affects gut microbiota and modulates hospitalization risk differentially in an international cirrhosis cohort.Hepatology2018
30241466ECPred: a tool for the prediction of the enzymatic functions of protein sequences based on the EC nomenclature.BMC Bioinformatics2018
30211975Object-Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images.Cytometry A2018
30251900Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents.J Enzyme Inhib Med Chem2018
30108969Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents.Medchemcomm2018
29783871EClerize: A customized force-directed graph drawing algorithm for biological graphs with EC attributes.J Bioinform Comput Biol2018
29371671Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines.Sci Rep2018
29326016Synthesis of novel 6-substituted amino-9-(β-d-ribofuranosyl)purine analogs and their bioactivities on human epithelial cancer cells.Bioorg Med Chem Lett2018
29098713Large-scale automated function prediction of protein sequences and an experimental case study validation on PTEN transcript variants.Proteins2018
28862295Synthesis of Some Substituted 6-Phenyl Purine Analogues and Their Biological Evaluation as Cytotoxic Agents.Acta Chim Slov2017
28403780Synthesis of Novel Benzothiazole-Piperazine Derivatives and Their Biological Evaluation as Acetylcholinesterase Inhibitors and Cytotoxic Agents.Anticancer Agents Med Chem2017
28219046Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics.Eur J Med Chem2017
29234806Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer.JAMA2017
26810835Novel triazolothiadiazines act as potent anticancer agents in liver cancer cells through Akt and ASK-1 proteins.Bioorg Med Chem2016
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Collaborators

Middle East Technical University
Co-authored papers 18
Hacettepe University
Co-authored papers 12
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 10
Iskenderun Technical University
Co-authored papers 10
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 3
Houston Methodist Research Institute
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Bilkent University
Co-authored papers 2
Middle East Technical University (METU)
Co-authored papers 2
Karolinska Institutet
Co-authored papers 1
Royal Holloway University of London
Co-authored papers 1
Institute of Biotechnology, University of Helsinki
Co-authored papers 1
UCL Great Ormond Street Institute of Child Health
Co-authored papers 1
Co-authored papers 1
Iowa State University
Co-authored papers 1
Co-authored papers 1
Institute of Nuclear Sciences Vinca, University of Belgrade
Co-authored papers 1
University of California Berkeley
Co-authored papers 1
Jozef Stefan Institute
Co-authored papers 1
Imperial College London
Co-authored papers 1
Universita degli Studi di Milano
Co-authored papers 1
United Institute of Informatics Problems
Co-authored papers 1
Institute of Nuclear Sciences VINCA, University of Belgrade
Co-authored papers 1
Medical University of Lodz
Co-authored papers 1
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University College London
Co-authored papers 1
Institute of Biomedical Engineering (IBME), University of Oxford
Co-authored papers 1
Universite de Lorraine, CNRS
Co-authored papers 1
Temple University
Co-authored papers 1
University of Toronto
Co-authored papers 1