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Author Details

Frederick Klauschen
Institute of Pathology, Ludwig-Maximilians-Universitat Munchen
2002
198
48
PMIDPaper TitleJournal TitlePublished Year
37871132Toward Explainable Artificial Intelligence for Precision Pathology.Annu Rev Pathol2024
36349502Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer.J Pathol Clin Res2023
37594677A Retrospective Analysis of Biliary Tract Cancer Patients Presented to the Molecular Tumor Board at the Comprehensive Cancer Center Munich.Target Oncol2023
37548948[Testing deficient mismatch repair and microsatellite instability : A focused update. German version].Pathologie (Heidelb)2023
37544709Tumour mutational burden and survival with molecularly matched therapy.Eur J Cancer2023
37542550Implementing precision oncology for sarcoma patients: the CCC<sup>LMU</sup>molecular tumor board experience.J Cancer Res Clin Oncol2023
37874379Testing for deficient mismatch repair and microsatellite instability : A focused update.Pathologie (Heidelb)2023
37641393Precision cancer medicine: Concepts, current practice, and future developments.J Intern Med2023
38034041Evaluation of the effectiveness of a nationwide precision medicine program for patients with advanced non-small cell lung cancer in Germany: a historical cohort analysis.Lancet Reg Health Eur2023
35796778Lessons learned: the first consecutive 1000 patients of the CCCMunich<sup>LMU</sup> Molecular Tumor Board.J Cancer Res Clin Oncol2023
35796776Immuno-histochemical correlation of fibrosis-related markers with the desmoplastic reaction of the mesentery in small intestine neuroendocrine neoplasms.J Cancer Res Clin Oncol2023
37345075TIM-3 Qualifies as a Potential Immunotherapeutic Target in Specific Subsets of Patients with High-Risk Soft Tissue Sarcomas (HR-STS).Cancers (Basel)2023
37080557Creation of a structured molecular genomics report for Germany as a local adaption of HL7's Genomic Reporting Implementation Guide.J Am Med Inform Assoc2023
37076398Intratumoral Heterogeneity of Molecular Subtypes in Muscle-invasive Bladder Cancer-An Extensive Multiregional Immunohistochemical Analysis.Eur Urol Focus2023
37369037Do skip-N2 metastases significantly impact overall survival and disease-free interval in N2 non-small-cell lung cancer patients? A multicentre analysis.Eur J Cardiothorac Surg2023
37062035Cancer of unknown primary (CUP) through the lens of precision oncology: a single institution perspective.J Cancer Res Clin Oncol2023
36519297Analysing cerebrospinal fluid with explainable deep learning: From diagnostics to insights.Neuropathol Appl Neurobiol2023
36853374Precision Oncology in Pancreatic Cancer: Experiences and Challenges of the CCCMunich<sup>LMU</sup> Molecular Tumor Board.Target Oncol2023
36748436The other colon cancer: a population-based cohort study of appendix tumour trends and prognosis.Colorectal Dis2023
36401637Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance.J Cancer Res Clin Oncol2023
36935856DNA-methylation and genomic copy number in primary tumors and corresponding lymph node metastases in prostate cancer from patients with low and high Gleason score.Clin Transl Radiat Oncol2023
36735063Structure and content of the EU-IVDR : Current status and implications for pathology.Pathologie (Heidelb)2023
36629274Single-cell gene regulatory network prediction by explainable AI.Nucleic Acids Res2023
34564861Mucosal melanomas of different anatomic sites share a common global DNA methylation profile with cutaneous melanoma but show location-dependent patterns of genetic and epigenetic alterations.J Pathol2022
35647009Diagnostic Accuracy of Magnetic Resonance Enterography for the Evaluation of Active and Fibrotic Inflammation in Crohn's Disease.Front Surg2022
35646657Liquid Biopsy in Colorectal Cancer: Quo Vadis? Implementation of Liquid Biopsies in Routine Clinical Patient Care in Two German Comprehensive Cancer Centers.Front Oncol2022
35403871[Artificial intelligence: a solution for the lack of pathologists?]Pathologe2022
35672443Patient-level proteomic network prediction by explainable artificial intelligence.NPJ Precis Oncol2022
35642679Correction to "Integration of Metabolomics and Expression of Glycerol-3-phosphate Acyltransferase (GPAM) in Breast Cancerâ¿¿Link to Patient Survival, Hormone Receptor Status, and Metabolic Profiling".J Proteome Res2022
35728978Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.Eur Respir J2022
35576834AURKA is a prognostic biomarker for good overall survival in stage II colorectal cancer patients.Pathol Res Pract2022
35763870Gene expression-based prediction of pazopanib efficacy in sarcoma.Eur J Cancer2022
35366396Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches.Immunity2022
35569281Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study.Eur J Cancer2022
35749951DNA methylation-based machine learning classification distinguishes pleural mesothelioma from chronic pleuritis, pleural carcinosis, and pleomorphic lung carcinomas.Lung Cancer2022
36443295DNA methylation-based classification of sinonasal tumors.Nat Commun2022
36544698Isolation and characterization of head and neck cancer-derived peritumoral and cancer-associated fibroblasts.Front Oncol2022
36045222Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.Lab Invest2022
36135637Deep Learning Assisted Diagnosis of Onychomycosis on Whole-Slide Images.J Fungi (Basel)2022
35901081Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas.PLoS One2022
35958344Prospective evaluation of immunological, molecular-genetic, image-based and microbial analyses to characterize tumor response and control in patients with unresectable stage III NSCLC treated with concurrent chemoradiotherapy followed by consolidation therapy with durvalumab (PRECISION): protocol for a prospective longitudinal biomarker study.Transl Lung Cancer Res2022
35955851Molecular Subtyping of Invasive Breast Cancer Using a PAM50-Based Multigene Expression Test-Comparison with Molecular-Like Subtyping by Tumor Grade/Immunohistochemistry and Influence on Oncologist's Decision on Systemic Therapy in a Real-World Setting.Int J Mol Sci2022
35892888Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL.Cancers (Basel)2022
35925306[Structure and content of the EU-IVDR : Current status and implications for pathology].Pathologie (Heidelb)2022
35983950Bcl-x<sub>L</sub> as prognostic marker and potential therapeutic target in cholangiocarcinoma.Liver Int2022
36347879New definitions of human lymphoid and follicular cell entities in lymphatic tissue by machine learning.Sci Rep2022
36191385DeepClassPathway: Molecular pathway aware classification using explainable deep learning.Eur J Cancer2022
36219392SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis.Cancer Res2022
33631297Artificial intelligence and pathology: From principles to practice and future applications in histomorphology and molecular profiling.Semin Cancer Biol2022
35185017A combination of immunohistochemical markers, MUC1, MUC5AC, PAX8 and growth pattern for characterization of mucinous neoplasm of the ovary.Int J Gynecol Cancer2022
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Collaborators

Institute of Pathology, University Hospital Heidelberg
Co-authored papers 60
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 33
Institute of Pathology, Charite Universitatsmedizin Berlin
Co-authored papers 24
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 17
Institute of Pathology, Ludwig-Maximilians-Universitat Munchen
Co-authored papers 16
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 16
German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT)
Co-authored papers 12
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 11
Charite University Medicine Berlin
Co-authored papers 10
Massachusetts General Hospital/Harvard Medical School
Co-authored papers 8
Pathologisches Institut, Universitatsklinikum Heidelberg
Co-authored papers 8
Otto-Friedrich-University Bamberg
Co-authored papers 8
German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)
Co-authored papers 6
Google Research
Co-authored papers 6
German Cancer Research Center (DKFZ)
Co-authored papers 6
German Cancer Consortium and German Cancer Research Center
Co-authored papers 6
University Medical Center Hamburg-Eppendorf
Co-authored papers 6
Institut fur Pathologie, Universitatsklinikum Heidelberg
Co-authored papers 5
Co-authored papers 5
Weill Cornell Medical College
Co-authored papers 5
German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)
Co-authored papers 5
University of Applied Sciences (HTW) Berlin
Co-authored papers 5
Co-authored papers 5
Co-authored papers 5
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 5
Yale University School of Medicine
Co-authored papers 5
Institut fur Pathologie, Universitatsklinikum Heidelberg
Co-authored papers 4
Cambridge University
Co-authored papers 4
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 4
National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ)
Co-authored papers 4