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Author Details

Sabine M Klauck
1987
97
34
PMIDPaper TitleJournal TitlePublished Year
37111592The Novel Artemisinin Dimer Isoniazide ELI-XXIII-98-2 Induces c-MYC Inhibition, DNA Damage, and Autophagy in Leukemia Cells.2023
37570631Modes of Action of a Novel c-MYC Inhibiting 1,2,4-Oxadiazole Derivative in Leukemia and Breast Cancer Cells.2023
37344563Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.2023
37322258The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells.2023
33884520Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells.Cell Biology and Toxicology2022
35878807Novel artemisinin derivative FO8643 with anti-angiogenic activity inhibits growth and migration of cancer cells via VEGFR2 signaling.European Journal of Pharmacology2022
36145342Modulation of Intestinal Corticotropin-Releasing Hormone Signaling by the Herbal Preparation STW 5-II: Possible Mechanisms for Irritable Bowel Syndrome Management.Pharmaceuticals2022
35985681Disruption of Lipid Raft Microdomains, Regulation of CD38, TP53, and MYC Signaling, and Induction of Apoptosis by Lomitapide in Multiple Myeloma Cells.Cancer Genomics and Proteomics2022
34582772Cytotoxicity of 4-hydroxy-N-(naphthalen-1-yl)-2-oxo-2H-chromene-3-carboxamide in multidrug-resistant cancer cells through activation of PERK/eIF2α/ATF4 pathway.Biochemical Pharmacology2021
33485866DNA Promoter Methylation and ERG Regulate the Expression of CD24 in Prostate Cancer.Am J Pathol2021
34111617Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids.Phytomedicine2021
33669024<i>miR-449a</i> Repression Leads to Enhanced NOTCH Signaling in <i>TMPRSS2:ERG</i> Fusion Positive Prostate Cancer Cells.Cancers (Basel)2021
34265280A novel moniliformin derivative as pan-inhibitor of histone deacetylases triggering apoptosis of leukemia cells.Biochemical Pharmacology2021
34021777Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation.Archives of Toxicology2021
333413102α-Hydroxyalantolactone from Pulicaria undulata: activity against multidrug-resistant tumor cells and modes of action.Phytomedicine2021
34832908Repurposing of the ALK Inhibitor Crizotinib for Acute Leukemia and Multiple Myeloma Cells.Pharmaceuticals2021
32957040Multiple modes of cell death in neuroendocrine tumors induced by artesunate.Phytomedicine2020
32624584Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder.Transl Psychiatry2020
32572023The role of rare compound heterozygous events in autism spectrum disorder.Transl Psychiatry2020
30668345Adaptogens in chemobrain (Part III): Antitoxic effects of plant extracts towards cancer chemotherapy-induced toxicity - transcriptome-wide microarray analysis of neuroglia cells.Phytomedicine2019
30901664Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells.Phytomedicine2019
30668446Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells.Phytomedicine2019
29147782Common functional variants of the glutamatergic system in Autism spectrum disorder with high and low intellectual abilities.J Neural Transm (Vienna)2018
29930110Analysis of shared heritability in common disorders of the brain.Science2018
30200539Genome-Based Classification and Therapy of Prostate Cancer.Diagnostics (Basel)2018
30515268Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation.Oncotarget2018
28445989TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells.Oncotarget2017
28912423The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through KEAP1-NRF2/HO-1 pathway.Scientific Reports2017
26564229Anticancer activity of cryptotanshinone on acute lymphoblastic leukemia cells.Archives of Toxicology2016
26926179Cryptotanshinone deregulates unfolded protein response and eukaryotic initiation factor signaling in acute lymphoblastic leukemia cells.Phytomedicine2016
25224256Variants of the CNTNAP2 5' promoter as risk factors for autism spectrum disorders: a genetic and functional approach.Molecular Psychiatry2015
26476154Molecular mechanisms of rosmarinic acid from Salvia miltiorrhiza in acute lymphoblastic leukemia cells.Journal of Ethnopharmacology2015
26472107Inhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells.Oncotarget2015
26290468A Novel Mutation in RPL10 (Ribosomal Protein L10) Causes X-Linked Intellectual Disability, Cerebellar Hypoplasia, and Spondylo-Epiphyseal Dysplasia.Hum Mutat2015
25250334Novel RNA markers in prostate cancer: functional considerations and clinical translation.Biomed Res Int2014
25363760Synaptic, transcriptional and chromatin genes disrupted in autism.Nature2014
25392729The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses.Mol Autism2014
24442360Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders.Human Genetics2014
24768552Convergence of genes and cellular pathways dysregulated in autism spectrum disorders.Am J Hum Genet2014
24512814Protein signatures of oxidative stress response in a patient specific cell line model for autism.Molecular Autism2014
23933821Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.Nat Genet2013
21996756A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder.Hum Genet2012
22843504Individual common variants exert weak effects on the risk for autism spectrum disorders.Hum Mol Genet2012
22346768Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders.PLoS Genet2012
21656903No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 gene and autism spectrum disorder.Am J Med Genet B Neuropsychiatr Genet2011
21442598[Genetic analyses for identifying molecular mechanisms in autism spectrum disorders].Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie2011
21472451[Genetics and animal modeling of autism spectrum disorders. New developments].Der Nervenarzt2011
21567917Mutation and expression analyses of the ribosomal protein gene RPL10 in an extended German sample of patients with autism spectrum disorder.American Journal of Medical Genetics, Part A2011
20663923A genome-wide scan for common alleles affecting risk for autism.Hum Mol Genet2010
20678249Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.Mol Autism2010
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