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Author Details

Adam J Engler
University of California
2004
131
49
PMIDPaper TitleJournal TitlePublished Year
36845078Age-dependent Lamin changes induce cardiac dysfunction via dysregulation of cardiac transcriptional programs.Nat Aging2023
37898021Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation.Biomaterials2023
37994565AP-1 signaling modulates cardiac fibroblast stress responses.J Cell Sci2023
37927406Using biophysical cues and biomaterials to improve genetic models.Curr Opin Biomed Eng2023
37342880Cell contractility drives mechanical memory of oral squamous cell carcinoma.Mol Biol Cell2023
37276403Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity.Proc Natl Acad Sci U S A2023
37404133Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity.Elife2023
37267912Getting physical: Material mechanics is an intrinsic cell cue.Cell Stem Cell2023
34826415Improved epicardial cardiac fibroblast generation from iPSCs.J Mol Cell Cardiol2022
35613278The Hippo pathway mediates Semaphorin signaling.Sci Adv2022
36406234Recent advancements and future requirements in vascularization of cortical organoids.Front Bioeng Biotechnol2022
36536804Mechanobiology of the cell nucleus.APL Bioeng2022
36195913Spatial transcriptomics tools allow for regional exploration of heterogeneous muscle pathology in the pre-clinical rabbit model of rotator cuff tear.J Orthop Surg Res2022
34861477Engineering the niche to differentiate and deploy cardiovascular cells.Curr Opin Biotechnol2022
35055055Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy.Int J Mol Sci2022
34258496Editorial: Understanding molecular interactions that underpin vascular mechanobiology.APL Bioeng2021
33769920Regenerative cross talk between cardiac cells and macrophages.Am J Physiol Heart Circ Physiol2021
33691109Adhesion strength and contractility enable metastatic cells to become adurotactic.Cell Rep2021
34106093Acetabular Bone Marrow Aspiration During Total Hip Arthroplasty.J Am Acad Orthop Surg2021
34327295High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3.APL Bioeng2021
34028746Atomic Force Microscopy for Live-Cell and Hydrogel Measurement.Methods Mol Biol2021
32396387Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274.Circ Genom Precis Med2020
31951109H-Ras Transformation of Mammary Epithelial Cells Induces ERK-Mediated Spreading on Low Stiffness Matrix.Adv Healthc Mater2020
31857292Cell Adhesiveness Serves as a Biophysical Marker for Metastatic Potential.Cancer Res2020
33195959Computational models of migration modes improve our understanding of metastasis.APL Bioeng2020
33243756EGFRvIII uses intrinsic and extrinsic mechanisms to reduce glioma adhesion and increase migration.J Cell Sci2020
32574556Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex.Dev Cell2020
32161833Multi-scale cellular engineering: From molecules to organ-on-a-chip.APL Bioeng2020
32161831Academic vs industry perspectives in 3D bioprinting.APL Bioeng2020
30559248Matrix stiffness mechanically conditions EMT and migratory behavior of oral squamous cell carcinoma.J Cell Sci2019
31326665Substrate stiffness directs diverging vascular fates.Acta Biomater2019
312513303D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress.Integr Biol (Camb)2019
30923642Combinatorial interactions of genetic variants in human cardiomyopathy.Nat Biomed Eng2019
30911429Mechanical activation of noncoding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes.Nat Biomed Eng2019
30794804Mechanical influences on cardiovascular differentiation and disease modeling.Exp Cell Res2019
30755531Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling.Proc Natl Acad Sci U S A2019
30515503Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis.Biomater Sci2019
30565321Fifteen years of Servitude et Grandeur to the application of a biophysical technique in medicine: The tale of AFMBioMed.J Mol Recognit2019
28755470The role of mechanobiology in progression of rotator cuff muscle atrophy and degeneration.J Orthop Res2018
30135582RAP2 mediates mechanoresponses of the Hippo pathway.Nature2018
30105314Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span.APL Bioeng2018
31069310Rationally engineered advances in cancer research.APL Bioeng2018
30416759Biomaterials to model and measure epithelial cancers.Nat Rev Mater2018
30528432Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing.Cell2018
29524630Extracellular matrix in lung development, homeostasis and disease.Matrix Biol2018
29283220Recent Advances in Extrusion-Based 3D Printing for Biomedical Applications.Adv Healthc Mater2018
29293645Heterogeneous muscle gene expression patterns in patients with massive rotator cuff tears.PLoS One2018
27699827Rotator cuff tear state modulates self-renewal and differentiation capacity of human skeletal muscle progenitor cells.J Orthop Res2017
28256233Metastatic State of Cancer Cells May Be Indicated by Adhesion Strength.Biophys J2017
28495800Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation.Mol Biol Cell2017
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Collaborators

Aditya Kumar
Rice University, University of California San Diego
Co-authored papers 14
Jesse K Placone
University of California San Diego
Co-authored papers 11
Samuel R Ward
Co-authored papers 9
Pranjali Beri
University California San Diego La Jolla
Co-authored papers 7
Matthew G Ondeck
University of California
Co-authored papers 6
Benjamin Yeoman
University of California
Co-authored papers 6
Valentina Lo Sardo
University of Wisconsin-Madison
Co-authored papers 5
Hugh Lee Sweeney
College of Medicine, University of Florida
Co-authored papers 5
Afsheen Banisadr
University of California
Co-authored papers 4
Jing Yang
University of California San Diego
Co-authored papers 4
Bibiana Franzen Matte
Federal University of Rio Grande do Sul.
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Moores Cancer Center, University of California
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University of California
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and Institute of Engineering in Medicine, University of California
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Stephanie I Fraley
University of California San Diego
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Bing Ren
Center for Epigenomics, University of California San Diego
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Shiley Eye Institute, University of California San Diego
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Parag Katira
San Diego State University
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Albert C Chen
University of California
Co-authored papers 2
Manoela Domingues Martins
Universidade Federal do Rio Grande do Sul
Co-authored papers 2
Kun-Liang Guan
University of California San Diego
Co-authored papers 2
Marcelo Lazzaron Lamers
Institute of Basic Health Sciences, Federal University of Rio Grande do Sul (UFRGS)
Co-authored papers 2
Evan M Masutani
University of California
Co-authored papers 2
Mingyi Wang
National Cancer Institute
Co-authored papers 2
Daniel Ortiz Velez
University of California San Diego
Co-authored papers 2
Cao Fang
University of California
Co-authored papers 2
Eric J Topol
Universidade Federal de Sao Paulo
Co-authored papers 2
Kathleen M Fisch
Center for Computational Biology and Bioinformatics, University of California
Co-authored papers 2
Rishi N Modi
University of California
Co-authored papers 2
Alysson R Muotri
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
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Release 1.2