Author details

Full Name

Jun Zhang

Affiliation

ORCID

Career Start Year

1997

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
25383718	Isoflurane protects the myocardium against ischemic injury via the preservation of mitochondrial respiration and its supramolecular organization.	Anesth Analg	2015
24070373	Characterization, design, and function of the mitochondrial proteome: from organs to organisms.	J Proteome Res	2014
23643589	Oxidative stress in atrial fibrillation: an emerging role of NADPH oxidase.	J Mol Cell Cardiol	2013
23022582	Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation.	J Proteomics	2013
22456183	Substrate- and isoform-specific proteome stability in normal and stressed cardiac mitochondria.	Circ Res	2012
22641634	Perspectives on: SGP symposium on mitochondrial physiology and medicine: mitochondrial proteome design: from molecular identity to pathophysiological regulation.	J Gen Physiol	2012
22915825	Metabolic labeling reveals proteome dynamics of mouse mitochondria.	Mol Cell Proteomics	2012
22679437	NOX4-Dependent Hydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 Atrial Cells: Relationship to Hypertension.	Front Physiol	2012
20495213	Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria.	Mol Cell Proteomics	2011
20093275	Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation.	Mol Cell Proteomics	2010
20004665	Netrin-1 prevents ischemia/reperfusion-induced myocardial infarction via a DCC/ERK1/2/eNOS s1177/NO/DCC feed-forward mechanism.	Journal of Molecular and Cellular Cardiology	2010
20299663	Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.	Circ Res	2010
19429835	Sepiapterin reductase regulation of endothelial tetrahydrobiopterin and nitric oxide bioavailability.	American Journal of Physiology - Heart and Circulatory Physiology	2009
19027023	Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.	J Mol Cell Cardiol	2009
18692063	Cyclin-dependent kinase 2 signaling regulates myocardial ischemia/reperfusion injury.	J Mol Cell Cardiol	2008
18988731	The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating.	Proc Natl Acad Sci U S A	2008
18348319	Systematic characterization of the murine mitochondrial proteome using functionally validated cardiac mitochondria.	Proteomics	2008
18468618	Acrolein consumption exacerbates myocardial ischemic injury and blocks nitric oxide-induced PKCepsilon signaling and cardioprotection.	Journal of Molecular and Cellular Cardiology	2008
18484766	Altered proteome biology of cardiac mitochondria under stress conditions.	J Proteome Res	2008
17673563	Past and present course of cardioprotection against ischemia-reperfusion injury.	J Appl Physiol (1985)	2007
16733263	Proteomics-based development of biomarkers in cardiovascular disease: mechanistic, clinical, and therapeutic insights.	Mol Cell Proteomics	2006
16857966	Mapping the murine cardiac 26S proteasome complexes.	Circ Res	2006
15528226	Functional proteomic analysis of a three-tier PKCepsilon-Akt-eNOS signaling module in cardiac protection.	Am J Physiol Heart Circ Physiol	2005
16093497	The murine cardiac 26S proteasome: an organelle awaiting exploration.	Ann N Y Acad Sci	2005
15191890	Bmx, a member of the Tec family of nonreceptor tyrosine kinases, is a novel participant in pharmacological cardioprotection.	Am J Physiol Heart Circ Physiol	2004
12829431	Cardioprotection involves activation of NF-kappa B via PKC-dependent tyrosine and serine phosphorylation of I kappa B-alpha.	Am J Physiol Heart Circ Physiol	2003
12663490	Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria.	Circ Res	2003
12840523	Functional proteomic analysis of the protein kinase C signaling system.	Methods Mol Biol	2003
14734831	Cardiac toxic effects of trans-2-hexenal are mediated by induction of cardiomyocyte apoptotic pathways.	Cardiovasc Toxicol	2003
11854322	Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection.	J Clin Invest	2002
11839754	Nitric oxide (NO) induces nitration of protein kinase Cepsilon (PKCepsilon ), facilitating PKCepsilon translocation via enhanced PKCepsilon -RACK2 interactions: a novel mechanism of no-triggered activation of PKCepsilon.	J Biol Chem	2002
12169683	Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS.	Mol Cell Proteomics	2002
11834516	Molecular conformation dictates signaling module formation: example of PKCepsilon and Src tyrosine kinase.	Am J Physiol Heart Circ Physiol	2002
11884367	Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection.	Circ Res	2002
11179034	PKCepsilon activation induces dichotomous cardiac phenotypes and modulates PKCepsilon-RACK interactions and RACK expression.	Am J Physiol Heart Circ Physiol	2001
11709417	Enhanced PKC beta II translocation and PKC beta II-RACK1 interactions in PKC epsilon-induced heart failure: a role for RACK1.	Am J Physiol Heart Circ Physiol	2001
11420308	Protein kinase C epsilon-Src modules direct signal transduction in nitric oxide-induced cardioprotection: complex formation as a means for cardioprotective signaling.	Circ Res	2001
11139474	Functional proteomic analysis of protein kinase C epsilon signaling complexes in the normal heart and during cardioprotection.	Circ Res	2001
11009455	PKCepsilon modulates NF-kappaB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes.	Am J Physiol Heart Circ Physiol	2000
10330229	PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits.	Am J Physiol	1999
10488057	Demonstration of selective protein kinase C-dependent activation of Src and Lck tyrosine kinases during ischemic preconditioning in conscious rabbits.	Circ Res	1999
10564130	PKC-dependent activation of p46/p54 JNKs during ischemic preconditioning in conscious rabbits.	Am J Physiol	1999
10082480	Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: a signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning.	Circ Res	1999
9833145	The nitric oxide hypothesis of late preconditioning.	Basic Res Cardiol	1998
9593774	Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that epsilon is the isoform involved.	J Clin Invest	1998
9285643	Ischemic preconditioning induces selective translocation of protein kinase C isoforms epsilon and eta in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity.	Circ Res	1997