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Author Details

Nels C Elde
University of Utah School of Medicine
2001
53
20
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37873270Hidden evolutionary constraints dictate the retention of coronavirus accessory genes.bioRxiv2024
36700640Virology under the Microscope-a Call for Rational Discourse.J Virol2023
37708888Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity.Curr Biol2023
37745432Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L.bioRxiv2023
37693489Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus.bioRxiv2023
37494187Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity.Cell Rep2023
37390614Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host-Microbe Arms Races beyond Canonical Protein-Protein Interfaces.Genome Biol Evol2023
36909515Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses.bioRxiv2023
36700653Virology under the Microscope-a Call for Rational Discourse.mSphere2023
36700642Virology under the Microscope-a Call for Rational Discourse.mBio2023
34958350Natural rodent model of viral transmission reveals biological features of virus population dynamics.J Exp Med2022
36477201Extensive Recombination-driven Coronavirus Diversification Expands the Pool of Potential Pandemic Pathogens.Genome Biol Evol2022
36417524Adaptive duplication and genetic diversification of protein kinase R contribute to the specificity of bat-virus interactions.Sci Adv2022
36069526Poxviruses capture host genes by LINE-1 retrotransposition.Elife2022
36356562When viruses do not go gentle into that good night.Cell Host Microbe2022
35245459Recurrent evolution of an inhibitor of ESCRT-dependent virus budding and LINE-1 retrotransposition in primates.Curr Biol2022
34358433Diarrheal pathogens trigger rapid evolution of the guanylate cyclase-C signaling axis in bats.Cell Host Microbe2021
33564759Extensive recombination-driven coronavirus diversification expands the pool of potential pandemic pathogens.bioRxiv2021
34752761Nels Elde.Curr Biol2021
34597582RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis.Cell2021
32195339Exploiting species specificity to understand the tropism of a human-specific toxin.Sci Adv2020
33370271Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network.PLoS Biol2020
32413307Linking Virus Discovery to Immune Responses Visualized during Zebrafish Infections.Curr Biol2020
30713099Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates.Cell Host Microbe2019
30156554Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays.Elife2018
27867194Regulatory activities of transposable elements: from conflicts to benefits.Nat Rev Genet2017
28854632Rapid Evolution of Primate Type 2 Immune Response Factors Linked to Asthma Susceptibility.Genome Biol Evol2017
27928012Emergence of a Viral RNA Polymerase Variant during Gene Copy Number Amplification Promotes Rapid Evolution of Vaccinia Virus.J Virol2017
26941318Regulatory evolution of innate immunity through co-option of endogenous retroviruses.Science2016
27506791Disruption of promoter memory by synthesis of a long noncoding RNA.Proc Natl Acad Sci U S A2016
27203426Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans.PLoS Genet2016
25618414Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.Virology2015
26625158Wham: Identifying Structural Variants of Biological Consequence.PLoS Comput Biol2015
26431675Buried Treasure: Evolutionary Perspectives on Microbial Iron Piracy.Trends Genet2015
26216977Baculovirus protein PK2 subverts eIF2α kinase function by mimicry of its kinase domain C-lobe.Proc Natl Acad Sci U S A2015
25831530cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.Proc Natl Acad Sci U S A2015
25942676Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.PLoS Genet2015
25533842DisAp-dependent striated fiber elongation is required to organize ciliary arrays.J Cell Biol2014
25504720Escape from bacterial iron piracy through rapid evolution of transferrin.Science2014
24005409Evolutionary biology: Mimicry all the way down.Nature2013
22901812Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses.Cell2012
23159048Poliovirus evolution: the strong, silent type.Cell Host Microbe2012
22835485A cross-species view on viruses.Curr Opin Virol2012
21643829Absence of positive selection on centromeric histones in Tetrahymena suggests unsuppressed centromere: drive in lineages lacking male meiosis.J Mol Evol2011
19043403Protein kinase R reveals an evolutionary model for defeating viral mimicry.Nature2009
19806153The evolutionary conundrum of pathogen mimicry.Nat Rev Microbiol2009
18701286A dynamin-related protein required for nuclear remodeling in Tetrahymena.Curr Biol2008
17329106A role for convergent evolution in the secretory life of cells.Trends Cell Biol2007
16933976Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote.PLoS Biol2006
15752136Core formation and the acquisition of fusion competence are linked during secretory granule maturation in Tetrahymena.Traffic2005
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Collaborators

Wesley I Sundquist
University of Utah School of Medicine
Co-authored papers 5
Kelsey R Cone
University of Utah
Co-authored papers 5
Aaron R Quinlan
University of Utah
Co-authored papers 4
Harmit S Malik
Fred Hutchinson Cancer Center
Co-authored papers 4
Mark Yandell
University of Utah
Co-authored papers 4
Patrizia Caposio
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
Mehul S Suthar
Co-authored papers 3
Alexander L Greninger
University of Washington Medical Center
Co-authored papers 3
Benjamin R tenOever
NYU Grossman School of Medicine
Co-authored papers 3
Britt A Glaunsinger
UC Berkeley
Co-authored papers 3
Jennifer M Lund
Fred Hutchinson Cancer Research Center
Co-authored papers 3
Stephen P Goff
Columbia University
Co-authored papers 3
Balaji Manicassamy
University of Iowa
Co-authored papers 3
Ana Fernandez-Sesma
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Michael Emerman
Fred Hutchinson Cancer Center
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Jay A Nelson
Oregon Health and Science University
Co-authored papers 3
Marco Vignuzzi
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
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Andrew D Yurochko
Louisiana State University
Co-authored papers 3
Rolf Renne
Co-authored papers 3
Adam S Lauring
University of Michigan ann arbor
Co-authored papers 3
Nicholas S Heaton
Duke University School of Medicine
Co-authored papers 3
Meaghan H Hancock
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
Benhur Lee
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Adrianus C M Boon
Co-authored papers 3
Charles M Rice
Rockefeller University
Co-authored papers 3
Matthew D Weitzman
The Children's Hospital of Philadelphia
Co-authored papers 3
Mark T Heise
University of North Carolina at Chapel Hill.
Co-authored papers 3
Arturo Casadevall
Johns Hopkins Bloomberg School of Public Health
Co-authored papers 3
Andrew Pekosz
Co-authored papers 3
Viviana Simon
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Release 1.2