Author details

Full Name

Hyunil Jo

Affiliation

Department of Pharmaceutical Chemistry, University of California San Francisco

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36824741	Designed Transmembrane Proteins Inhibit the Erythropoietin Receptor in a Custom Binding Topology.	bioRxiv	2023
37632140	Hexamethylene amiloride binds the SARS-CoV-2 envelope protein at the protein-lipid interface.	Protein Sci	2023
38014268	<i>De novo</i> Design of Peptides that Bind Specific Conformers of Î±-Synuclein.	bioRxiv	2023
37425793	Patterning and folding of intestinal villi by active mesenchymal dewetting.	bioRxiv	2023
35080027	Brilacidin, a COVID-19 drug candidate, demonstrates broad-spectrum antiviral activity against human coronaviruses OC43, 229E, and NL63 through targeting both the virus and the host cell.	J Med Virol	2022
36219675	SARS-CoV-2 Envelope Protein Forms Clustered Pentamers in Lipid Bilayers.	Biochemistry	2022
35082148	Soluble TREM2 inhibits secondary nucleation of AÎ² fibrillization and enhances cellular uptake of fibrillar AÎ².	Proc Natl Acad Sci U S A	2022
33956668	Integrin Î±2Î²1 regulates collagen I tethering to modulate hyperresponsiveness in reactive airway disease models.	J Clin Invest	2021
34010565	Visualization of Platelet Integrins via Two-Photon Microscopy Using Anti-transmembrane Domain Peptides Containing a Blue Fluorescent Amino Acid.	Biochemistry	2021
33007395	Dual antagonists of Î±5Î²1/Î±vÎ²1 integrin for airway hyperresponsiveness.	Bioorg Med Chem Lett	2020
30957824	Synthesis and application of the blue fluorescent amino acid l-4-cyanotryptophan to assess peptide-membrane interactions.	Chem Commun (Camb)	2019
30744004	4-Cyanoindole-2'-deoxyribonucleoside as a Dual Fluorescence and Infrared Probe of DNA Structure and Dynamics.	Molecules	2019
30998340	Glutamine Side Chain <sup>13</sup>Câ¿<sup>18</sup>O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly.	J Am Chem Soc	2019
29417711	Design of a Short Thermally Stable Î±-Helix Embedded in a Macrocycle.	Chembiochem	2018
30102523	Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule.	Biochemistry	2018
30532032	Inhibitor binding mode and allosteric regulation of Na<sup>+</sup>-glucose symporters.	Nat Commun	2018
27918306	Targeting integrin Î±5Î²1 ameliorates severe airway hyperresponsiveness in experimental asthma.	J Clin Invest	2017
28278376	Stapled Voltage-Gated Calcium Channel (Ca<sub>V</sub>) Î±-Interaction Domain (AID) Peptides Act As Selective Protein-Protein Interaction Inhibitors of Ca<sub>V</sub> Function.	ACS Chem Neurosci	2017
28406028	Water Distribution, Dynamics, and Interactions with Alzheimer's Î²-Amyloid Fibrils Investigated by Solid-State NMR.	J Am Chem Soc	2017
28220032	Pharmacologic Blockade of <i>Î±</i>v<i>Î²</i>1 Integrin Ameliorates Renal Failure and Fibrosis <i>In Vivo</i>.	J Am Soc Nephrol	2017
28533371	Blue fluorescent amino acid for biological spectroscopy and microscopy.	Proc Natl Acad Sci U S A	2017
27220724	Photoactivatable protein labeling by singlet oxygen mediated reactions.	Bioorg Med Chem Lett	2016
27725984	Infrared and fluorescence assessment of the hydration status of the tryptophan gate in the influenza A M2 proton channel.	Phys Chem Chem Phys	2016
27774126	Exploring <i>N</i>-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective Î±vÎ²1 Integrin Inhibitors.	ACS Med Chem Lett	2016
27414264	Structural Polymorphism of Alzheimer's Î²-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study.	J Am Chem Soc	2016
25995225	The Î±vÎ²1 integrin plays a critical in vivo role in tissue fibrosis.	Sci Transl Med	2015
25470189	Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.	J Am Chem Soc	2014
23437766	Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.	J Med Chem	2013
24205975	Assessment of local friction in protein folding dynamics using a helix cross-linker.	J Phys Chem B	2013
22210111	Affinity of talin-1 for the Î²3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.	Proc Natl Acad Sci U S A	2012
23245326	Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials.	Cell Host Microbe	2012
22998171	Development of Î±-helical calpain probes by mimicking a natural protein-protein interaction.	J Am Chem Soc	2012
22440900	Inhibition of integrin Î±2Î²1 ameliorates glomerular injury.	J Am Soc Nephrol	2012
22540162	Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in Î²-sheet folding.	J Am Chem Soc	2012
20547797	Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.	Antimicrob Agents Chemother	2010
21077670	Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation.	Biochemistry	2010
19301922	An unusual pathway to cyclobutane formation via desulfurative intramolecular photocycloaddition of an enone benzothiazoline pair.	Org Lett	2009
15624981	Highly stereoselective and efficient total synthesis of (+)-laurencin.	Org Lett	2005
11856018	Asymmetric total synthesis of (+)-brefeldin A from (S)-lactate by triple chirality transfer process and nitrile oxide cycloaddition.	J Org Chem	2002

1 - 39 of 39

Michael J Robertson

Stanford University School of Medicine

Career Start Year 2015

Number of shared co-authors 0

Zhi Lin

Shanghai Jiao Tong University

Career Start Year 2012

Number of shared co-authors 1

Daniel Carbajo

Institut de Quimica Avancada de Catalunya (IQAC-CSIC)

Career Start Year 2011

Number of shared co-authors 0

Amit Choudhary

Broad Institute of MIT and Harvard

Career Start Year 2009

Number of shared co-authors 0

Xiaofei Jia

University of Massachusetts Dartmouth

Career Start Year 2008

Number of shared co-authors 1

Andrew C Kruse

Blavatnik Institute, Harvard Medical School

Career Start Year 2008

Number of shared co-authors 2

Nir London

The Weizmann Institute of Science

Career Start Year 2007

Number of shared co-authors 4

Suwen Zhao

ShanghaiTech University, China iHuman Institute

Career Start Year 2006

Number of shared co-authors 3

Jianwei Che

Dana-Farber Cancer Institute

Career Start Year 2005

Number of shared co-authors 0

Priyadarshini Jaishankar

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2005

Number of shared co-authors 1

Andrew B Waight

Merck & Co.

Career Start Year 2003

Number of shared co-authors 1

Jason E Gestwicki

Institute for Neurodegenerative Diseases, University of California San Francisco

Career Start Year 2000

Number of shared co-authors 7

R Scott Lokey

University of California Santa Cruz

Career Start Year 2000

Number of shared co-authors 2

Udupi A Ramagopal

Poornaprajna Institute of Scientific Research (PPISR)

Career Start Year 1998

Number of shared co-authors 1

Pavel Strop

Pfizer Inc.

Career Start Year 1997

Number of shared co-authors 1

Soumya S Ray

Lysosomal Therapeutics Inc.

Career Start Year 1997

Number of shared co-authors 1

Rodrigo J Carbajo

Oncology R&D

Career Start Year 1997

Number of shared co-authors 1

Adam R Renslo

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 1997

Number of shared co-authors 6

Jack Taunton

University of California san francisco

Career Start Year 1996

Number of shared co-authors 6

Witek Kwiatkowski

Swiss Federal Institute of Technology

Career Start Year 1996

Number of shared co-authors 2

Hualiang Jiang

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Career Start Year 1994

Number of shared co-authors 0

Dieter Willbold

Institute of Physical Biology, Heinrich Heine University Dusseldorf

Career Start Year 1993

Number of shared co-authors 1

Steven C Almo

Albert Einstein College of Medicine

Career Start Year 1988

Number of shared co-authors 3

Raymond C Stevens

iHuman Institute, ShanghaiTech University

Career Start Year 1988

Number of shared co-authors 1

Laura L Kiessling

Massachusetts Institute of Technology

Career Start Year 1987

Number of shared co-authors 0

Ronald T Raines

Massachusetts Institute of Technology

Career Start Year 1981

Number of shared co-authors 0

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Career Start Year 1981

Number of shared co-authors 0

James A Wells

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 1974

Number of shared co-authors 6

Horst Kessler

Institute for Advanced Study, Technical University Munich

Career Start Year 1966

Number of shared co-authors 2

Jens Meiler

Vanderbilt University

Career Start Year 1954

Number of shared co-authors 3

row(s) 1 - 30 of 30

William F DeGrado

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 35

Aparna Sundaram

Formerly with the Guttmacher Institute.

Co-authored papers 3

Haifan Wu

Wichita State University

Co-authored papers 3

Huong T Kratochvil

Department of Pharmaceutical Chemistry, University of California-San Francisco

Co-authored papers 3

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 2

Thomas Lemmin

Co-authored papers 2

Carlo Condello

UCSF Weill Institute for Neurosciences, University of California san francisco

Co-authored papers 2

Shaun R Coughlin

Co-authored papers 1

Erika Castillo

Institute for Neurodegenerative Diseases, University of California san francisco

Co-authored papers 1

Paola Bisignano

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Co-authored papers 1

Daniel J Saltzberg

University of California san francisco

Co-authored papers 1

David E Shaw

Columbia University

Co-authored papers 1

Kala Bharath Pilla

Quantitative Biology Institute, University of California san francisco

Co-authored papers 1

Daniel L Minor

Cardiovascular Research Institute, University of California san francisco

Co-authored papers 1

Kathleen S Molnar

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 1

Ji Jin

College of Life Sciences and Medicine, Zhejiang Sci-Tech University

Co-authored papers 1

Xiaokun Shu

Co-authored papers 1

Jan St??hr

Weill Institute for Neurosciences, University of California san francisco

Co-authored papers 1

Stanley B Prusiner

Weill Institute for Neurosciences, University of California San Francisco

Co-authored papers 1

Annalise Bond

Institute for Neurodegenerative Diseases, University of California san francisco

Co-authored papers 1

Matthew P Jacobson

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Chakrapani Kalyanaraman

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Matt Thomson

California Institute of Technology

Co-authored papers 1

Melissa S Love

a Division of The Scripps Research Institute

Co-authored papers 1

John W Weisel

University of Pennsylvania

Co-authored papers 1

Ketaki D Belsare

The University of Chicago

Co-authored papers 1

Addison E Roush

Co-authored papers 1

Alma L Burlingame

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

1 - 28

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