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Author Details

Helen R Saibil
Institute of Structural and Molecular Biology, University of London
1976
169
68
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36646960A structural basis for prion strain diversity.Nat Chem Biol2023
38064510Structural basis of substrate progression through the bacterial chaperonin cycle.Proc Natl Acad Sci U S A2023
36646960A structural basis for prion strain diversity.Nat Chem Biol2023
37443175Structural journey of an insecticidal protein against western corn rootworm.Nat Commun2023
37528099Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites.Nat Commun2023
37528099Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites.Nat Commun2023
38064510Structural basis of substrate progression through the bacterial chaperonin cycle.Proc Natl Acad Sci U S A2023
37443175Structural journey of an insecticidal protein against western corn rootworm.Nat Commun2023
35063096Cryo-EM in molecular and cellular biology.Mol Cell2022
358312752.7⿿ÿ cryo-EM structure of ex vivo RML prion fibrils.Nat Commun2022
35698800Cooperative amyloid fibre binding and disassembly by the Hsp70 disaggregase.EMBO J2022
36285779Pushing the limits in single particle cryo-EM: general discussion.Faraday Discuss2022
36218050Spiers Memorial Lecture: Challenges in cryo electron microscopy.Faraday Discuss2022
36278863Sample preparation in single particle cryo-EM: general discussion.Faraday Discuss2022
36254744Map/model validation and machine learning in EM: general discussion.Faraday Discuss2022
35063096Cryo-EM in molecular and cellular biology.Mol Cell2022
35148176The pore conformation of lymphocyte perforin.Sci Adv2022
35698800Cooperative amyloid fibre binding and disassembly by the Hsp70 disaggregase.EMBO J2022
358312752.7⿿ÿ cryo-EM structure of ex vivo RML prion fibrils.Nat Commun2022
36278863Sample preparation in single particle cryo-EM: general discussion.Faraday Discuss2022
36285779Pushing the limits in single particle cryo-EM: general discussion.Faraday Discuss2022
36254744Map/model validation and machine learning in EM: general discussion.Faraday Discuss2022
36218050Spiers Memorial Lecture: Challenges in cryo electron microscopy.Faraday Discuss2022
35148176The pore conformation of lymphocyte perforin.Sci Adv2022
34021280REMBI: Recommended Metadata for Biological Images-enabling reuse of microscopy data in biology.Nat Methods2021
33853668Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington's disease.Acta Neuropathol Commun2021
33688001Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony.mBio2021
33957121The PDB and protein homeostasis: From chaperones to degradation and disaggregase machines.J Biol Chem2021
34021280REMBI: Recommended Metadata for Biological Images-enabling reuse of microscopy data in biology.Nat Methods2021
33853668Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington's disease.Acta Neuropathol Commun2021
33688001Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony.mBio2021
33957121The PDB and protein homeostasis: From chaperones to degradation and disaggregase machines.J Biol Chem2021
30675000Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro.Sci Rep2019
31216466Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.Cell Rep2019
30675000Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro.Sci Rep2019
31200186Cryo-EM of amyloid fibrils and cellular aggregates.Curr Opin Struct Biol2019
31216466Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.Cell Rep2019
31200186Cryo-EM of amyloid fibrils and cellular aggregates.Curr Opin Struct Biol2019
29459732A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.Nat Microbiol2018
29959019A two-domain folding intermediate of RuBisCO in complex with the GroEL chaperonin.Int J Biol Macromol2018
29754822A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation.Mol Cell2018
29511275Publisher Correction: A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.Nat Microbiol2018
29459732A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.Nat Microbiol2018
29416110Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.Cell Death Differ2018
29959019A two-domain folding intermediate of RuBisCO in complex with the GroEL chaperonin.Int J Biol Macromol2018
29754822A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation.Mol Cell2018
29416110Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.Cell Death Differ2018
29511275Publisher Correction: A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.Nat Microbiol2018
28682240Building bridges between cellular and molecular structural biology.Elife2017
28859647Blob-ology and biology of cryo-EM: an interview with Helen Saibil.BMC Biol2017
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Collaborators

Maya Topf
Leibniz-Institut fur Virologie (LIV)
Co-authored papers 8
James C Whisstock
Monash University
Co-authored papers 7
Kay Gr??newald
Leibniz Institute of Virology
Co-authored papers 5
Carol V Robinson
University of Oxford
Co-authored papers 4
Gerard J Kleywegt
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 4
Christopher M Dobson
University of Cambridge
Co-authored papers 4
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European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 4
Jason R Swedlow
University of Dundee
Co-authored papers 3
Wah Chiu
Stanford University
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Lucy M Collinson
Co-authored papers 3
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Elizabeth Duke
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Susan Lindquist
Whitehead Institute for Biomedical Research
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Sjors H W Scheres
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Stephen K Burley
The State University of New Jersey
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Jean-Karim H??rich??
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The State University of New Jersey
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David I Stuart
University of Oxford
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John D Westbrook
The State University of New Jersey
Co-authored papers 2
Helen Parkinson
European Bioinformatics Institute
Co-authored papers 2
Scott M Stagg
Florida State University
Co-authored papers 2
Andrzej Joachimiak
Center for Structural Biology of Infectious Diseases, University of Chicago
Co-authored papers 2
Paul Verkade
Co-authored papers 2
Konstantinos Thalassinos
Institute of Structural and Molecular Biology, University of London
Co-authored papers 2
Gaetano T Montelione
Rensselaer Polytechnic Institute
Co-authored papers 2
Maria Harkiolaki
Co-authored papers 2
Torsten Schwede
University of Basel
Co-authored papers 2
Andrii Iudin
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
Release 1.2