Author details

Full Name

Edward Lau

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36711879	Simultaneous proteome localization and turnover analysis reveals spatiotemporal features of protein homeostasis disruptions.	bioRxiv	2024
37456137	Senescence in human AC16 cardiac cells is associated with thymidine kinase induction and histone loss.	MicroPubl Biol	2023
35209901	MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes.	Cardiovascular Diabetology	2022
36356032	Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners.	PLoS Comput Biol	2022
35821831	Defining the Roles of Cardiokines in Human Aging and Age-Associated Diseases.		2022
35750035	Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation.	Cell	2022
35636728	Harmonizing Labeling and Analytical Strategies to Obtain Protein Turnover Rates in Intact Adult Animals.	Molecular and Cellular Proteomics	2022
35489334	Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation.	Cell	2022
35930447	Proteogenomics reveals sex-biased aging genes and coordinated splicing in cardiac aging.	Am J Physiol Heart Circ Physiol	2022
36053749	Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF.	Am J Physiol Heart Circ Physiol	2022
34779440	Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot.	J Vis Exp	2021
33830086	Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies.	JCI Insight	2021
34139234	Serum response factor deletion 5 regulates phospholamban phosphorylation and calcium uptake.	J Mol Cell Cardiol	2021
33549679	Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart.	J Mol Cell Cardiol	2021
34328155	Transcriptome features of striated muscle aging and predictability of protein level changes.	Mol Omics	2021
32668256	Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.	Cell Reports	2020
33377032	Determining Alternative Protein Isoform Expression Using RNA Sequencing and Mass Spectrometry.	STAR Protoc	2020
32584494	High-throughput Preparation of DNA, RNA, and Protein from Cryopreserved Human iPSCs for Multi-omics Analysis.	Current Protocols in Stem Cell Biology	2020
33136510	Atlas of Exosomal microRNAs Secreted From Human iPSC-Derived Cardiac Cell Types.	Circulation	2020
33116222	Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart.	Sci Rep	2020
31316208	Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.	Nature	2019
31825849	Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome.	Cell Rep	2019
30586709	A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay.	Circulation	2019
30379619	Systems-Wide Approaches in Induced Pluripotent Stem Cell Models.	Annual Review of Pathology: Mechanisms of Disease	2019
29317621	Integrated omics dissection of proteome dynamics during cardiac remodeling.	Nat Commun	2018
30256117	Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity.	J Proteome Res	2018
29721363	Prolonged survival of transplanted stem cells after ischaemic injury via the slow release of pro-survival peptides from a collagen matrix.	Nature Biomedical Engineering	2018
29301998	NextGen VOICES: Research resolutions.	Science	2018
29700063	Omics, Big Data, and Precision Medicine in Cardiovascular Sciences.	Circulation Research	2018
27980500	Cardiovascular proteomics in the era of big data: experimental and computational advances.	Clin Proteomics	2016
26977904	A large dataset of protein dynamics in the mammalian heart proteome.	Sci Data	2016
26955516	Alpha desynchronization and fronto-parietal connectivity during spatial working memory encoding deficits in ADHD: A simultaneous EEG-fMRI study.	NeuroImage: Clinical	2016
27356587	Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems.	J Proteome Res	2016
27482534	An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults.	eNeuro	2016
27481999	Connecting the Dots: From Big Data to Healthy Heart.	Circulation	2016
27444931	Identifying Low-Abundance Biomarkers: Aptamer-Based Proteomics Potentially Enables More Sensitive Detection in Cardiovascular Diseases.	Circulation	2016
26587667	Label-Free Quantitative Proteomics Reveals Survival Mechanisms Developed by Hypertrophic Chondrocytes under ER Stress.	Journal of Proteome Research	2016
26160638	Prioritizing Proteomics Assay Development for Clinical Translation.	J Am Coll Cardiol	2015
25752359	Spatial and temporal dynamics of the cardiac mitochondrial proteome.	Expert Rev Proteomics	2015
25451168	Mitochondrial protein turnover: methods to measure turnover rates on a large scale.	J Mol Cell Cardiol	2015
24957502	Lysine ubiquitination and acetylation of human cardiac 20S proteasomes.	Proteomics Clin Appl	2014
25311448	Multimodal diagnosis of epilepsy using conditional dependence and multiple imputation.	Int Workshop Pattern Recognit Neuroimaging	2014
24070373	Characterization, design, and function of the mitochondrial proteome: from organs to organisms.	J Proteome Res	2014
24429915	Method for simultaneous fMRI/EEG data collection during a focused attention suggestion for differential thermal sensation.	J Vis Exp	2014
24946186	Characterization of human plasma proteome dynamics using deuterium oxide.	Proteomics Clin Appl	2014
24614109	Protein kinetic signatures of the remodeling heart following isoproterenol stimulation.	J Clin Invest	2014
23625949	Response to Pomozi et al's research commentary.	Circ Res	2013
25302313	Balancing Clinical and Pathologic Relevence in the Machine Learning Diagnosis of Epilepsy.	Int Workshop Pattern Recognit Neuroimaging	2013
23022582	Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation.	J Proteomics	2013
23914164	Single trial decoding of belief decision making from EEG and fMRI data using independent components features.	Front Hum Neurosci	2013