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Author Details

David J Lynn
South Australian Health and Medical Research Institute
2002
93
38
PMIDPaper TitleJournal TitlePublished Year
37932511Role of the microbiota in response to and recovery from cancer therapy.Nat Rev Immunol2024
37500502B and T cell responses to the BNT162b2 COVID-19 mRNA vaccine are not impaired in germ-free or antibiotic-treated mice.Gut2024
36834715Selective Transcription Factor Blockade Reduces Human Retinal Endothelial Cell Expression of Intercellular Adhesion Molecule-1 and Leukocyte Binding.Int J Mol Sci2023
37673961Targeting hyaluronan-mediated motility receptor (HMMR) enhances response to androgen receptor signalling inhibitors in prostate cancer.Br J Cancer2023
37471143No evidence of durable trained immunity after two doses of adenovirus-vectored or mRNA COVID-19 vaccines.J Clin Invest2023
36871558A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines.Cell Rep Med2023
34002068Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms.Nat Rev Immunol2022
35654046SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents.Cell Rep Med2022
35406480Harnessing the Heterogeneity of Prostate Cancer for Target Discovery Using Patient-Derived Explants.Cancers (Basel)2022
36595955Protocol to colonize gnotobiotic mice in early life and assess the impact on early life immune programming.STAR Protoc2022
36018584Transcriptomic Responses of Human Retinal Vascular Endothelial Cells to Inflammatory Cytokines.Transl Vis Sci Technol2022
33895015Immunisation with the BCG and DTPw vaccines induces different programs of trained immunity in mice.Vaccine2022
35284839Protocol to assess the impact of early-life antibiotic exposure on murine longevity.STAR Protoc2022
32460321National Trends in Antibiotic Use in Australian Residential Aged Care Facilities, 2005-2016.Clin Infect Dis2021
33580681Contribution of facility level factors to variation in antibiotic use in long-term care facilities: a national cohort study.J Antimicrob Chemother2021
35028606The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota.Cell Rep Med2021
34433065The composition of the gut microbiota following early-life antibiotic exposure affects host health and longevity in later life.Cell Rep2021
34632317OX40-targeted immune agonist antibodies induce potent antitumor immune responses without inducing liver damage in mice.FASEB Bioadv2021
34711598BCG vaccination to reduce the impact of COVID-19 in healthcare workers: Protocol for a randomised controlled trial (BRACE trial).BMJ Open2021
33968035Zika Virus Infection of Human Iris Pigment Epithelial Cells.Front Immunol2021
34362796Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition.Cancer Res2021
32461674The non-specific and sex-differential effects of vaccines.Nat Rev Immunol2020
31980649Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS<sup>G13D</sup>.Nat Commun2020
33262342Towards a unified open access dataset of molecular interactions.Nat Commun2020
32669400Fatty Acid Oxidation Is an Adaptive Survival Pathway Induced in Prostate Tumors by HSP90 Inhibition.Mol Cancer Res2020
31133691Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRAS<sup>G13D</sup> mutation.Br J Cancer2019
31662429Changes in the Composition of the Gut Microbiota and the Blood Transcriptome in Preterm Infants at Less than 29 Weeks Gestation Diagnosed with Bronchopulmonary Dysplasia.mSystems2019
28864446The potential of the microbiota to influence vaccine responses.J Leukoc Biol2018
30054594Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.Nat Genet2018
30168906Analysis and Visualization of Dynamic Networks Using the DyNet App for Cytoscape.Curr Protoc Bioinformatics2018
29449654Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma.Sci Rep2018
29391407Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion.Sci Rep2018
29753646Network Visualization and Analysis of Spatially Aware Gene Expression Data with InsituNet.Cell Syst2018
29642841Encompassing new use cases - level 3.0 of the HUPO-PSI format for molecular interactions.BMC Bioinformatics2018
29746836Early-Life Antibiotic-Driven Dysbiosis Leads to Dysregulated Vaccine Immune Responses in Mice.Cell Host Microbe2018
29632047Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants.Mol Cell Proteomics2018
28902399Using the Contextual Hub Analysis Tool (CHAT) in Cytoscape to Identify Contextually Relevant Network Hubs.Curr Protoc Bioinformatics2017
28264060Whole exome sequencing implicates eye development, the unfolded protein response and plasma membrane homeostasis in primary open-angle glaucoma.PLoS One2017
28721309Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye.Transl Vis Sci Technol2017
27036106Using biological networks to integrate, visualize and analyze genomics data.Genet Sel Evol2016
27217537Interferon-driven alterations of the host's amino acid metabolism in the pathogenesis of typhoid fever.J Exp Med2016
27153624DyNet: visualization and analysis of dynamic molecular interaction networks.Bioinformatics2016
26960806A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23.Genet Sel Evol2016
27086506HiQuant: Rapid Postquantification Analysis of Large-Scale MS-Generated Proteomics Data.J Proteome Res2016
25692199MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking.Tuberculosis (Edinb)2015
26653414Erratum to: 'Integrated analysis of the local and systemic changes preceding the development of post-partum cytological endometritis'.BMC Genomics2015
26482908Integrated analysis of the local and systemic changes preceding the development of post-partum cytological endometritis.BMC Genomics2015
25953080CerebralWeb: a Cytoscape.js plug-in to visualize networks stratified by subcellular localization.Database (Oxford)2015
24470219MicroRNA regulation of bovine monocyte inflammatory and metabolic networks in an in vivo infection model.G3 (Bethesda)2014
26484146Whole blood gene expression profiling of neonates with confirmed bacterial sepsis.Genom Data2014
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Collaborators

Simon Fraser University
Co-authored papers 11
University of British Columbia
Co-authored papers 7
College of Medicine and Public Health, Flinders University
Co-authored papers 4
Co-authored papers 3
Telethon Kids Institute
Co-authored papers 3
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 3
Schroeder Arthritis Institute
Co-authored papers 3
EMBL's European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 3
Lions Eye Institute, University of Western Australia
Co-authored papers 3
Adelaide Medical School, University of Adelaide
Co-authored papers 3
ICBMS UMR CNRS 5246, University Lyon 1
Co-authored papers 3
Menzies Institute for Medical Research, University of Tasmania
Co-authored papers 3
European Bioinformatics Institute
Co-authored papers 3
university of california los angeles
Co-authored papers 3
Flinders Medical Centre, Flinders University
Co-authored papers 3
University of Rome 'Tor Vergata'
Co-authored papers 3
KTH-Royal Institute of Technology
Co-authored papers 2
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
University of Tor Vergata
Co-authored papers 2
Co-authored papers 2
University of Washington School of Medicine
Co-authored papers 2
Universita della Calabria
Co-authored papers 2
Simon Fraser University
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Co-authored papers 2
Smurfit Institute of Genetics, Trinity College of Dublin
Co-authored papers 2
University of Geneva Medical School
Co-authored papers 2
UK System Immunity Research Institute, Cardiff University
Co-authored papers 2