Author details

Full Name

Patrice M Milos

Affiliation

ORCID

Career Start Year

1982

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
27090146	Orthogonal NGS for High Throughput Clinical Diagnostics.	Sci Rep	2016
25100654	Deadenylase depletion protects inherited mRNAs in primordial germ cells.	Development	2014
24658703	Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6.	PLoS ONE	2014
23563143	On the importance of small changes in RNA expression.	Methods	2013
23636849	Somatic alterations contributing to metastasis of a castration-resistant prostate cancer.	Hum Mutat	2013
22144202	Profiling of short RNAs using Helicos single-molecule sequencing.	Methods in Molecular Biology	2012
22753024	An in-depth map of polyadenylation sites in cancer.	Nucleic Acids Res	2012
22531001	Genome-wide identification and characterization of replication origins by deep sequencing.	Genome Biol	2012
22820990	Direct sequencing of Arabidopsis thaliana RNA reveals patterns of cleavage and polyadenylation.	Nature Structural and Molecular Biology	2012
22763454	RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis.	Nature	2012
21765009	Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations.	Genome Research	2012
21875357	Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencing.	Human Gene Therapy	2012
21552279	Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.	Nature	2011
21349208	The properties and applications of single-molecule DNA sequencing.		2011
21390249	A comparison of single molecule and amplification based sequencing of cancer transcriptomes.	PLoS One	2011
21431761	RNA sequencing and quantitation using the Helicos Genetic Analysis System.	Methods in Molecular Biology	2011
21431762	Transcriptome profiling using single-molecule direct RNA sequencing.	Methods in Molecular Biology	2011
21431759	Helicos single-molecule sequencing of bacterial genomes.	Methods in Molecular Biology	2011
21191423	RNA sequencing: advances, challenges and opportunities.	Nature Reviews Genetics	2011
21573114	Protocol dependence of sequencing-based gene expression measurements.	PLoS ONE	2011
21957044	Single-molecule direct RNA sequencing without cDNA synthesis.	Wiley interdisciplinary reviews. RNA	2011
20580974	Single-molecule sequencing: sequence methods to enable accurate quantitation.	Methods in Enzymology	2010
21176148	The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA.	BMC Biol	2010
21124451	The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.	Nature	2010
21145465	Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation.	Cell	2010
19946276	Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.	Nat Methods	2010
20133332	Digital transcriptome profiling from attomole-level RNA samples.	Genome Res	2010
20639869	Amplification-free digital gene expression profiling from minute cell quantities.	Nat Methods	2010
20671709	New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism.	Nature	2010
19817551	Emergence of single-molecule sequencing and potential for molecular diagnostic applications.	Expert Review of Molecular Diagnostics	2009
19581875	Quantification of the yeast transcriptome by single-molecule sequencing.	Nature Biotechnology	2009
19776739	Direct RNA sequencing.	Nature	2009
18193046	Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.	Nat Genet	2008
18384261	Helicos BioSciences.	Pharmacogenomics	2008
17728769	New models of collaboration in genome-wide association studies: the Genetic Association Information Network.	Nat Genet	2007
17096118	Paraoxonase 2 (PON2) polymorphisms and development of renal dysfunction in type 2 diabetes: UKPDS 76.	Diabetologia	2006
17161064	Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes.	American Heart Journal	2006
16338273	Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests.	Clin Pharmacol Ther	2005
15939053	CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease.	Atherosclerosis	2005
16103896	An association study of 43 SNPs in 16 candidate genes with atorvastatin response.	Pharmacogenomics Journal	2005
15681846	Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.	Journal of Biological Chemistry	2005
14984737	Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels.		2004
15450208	Highly polymorphic repeat region in the CETP promoter induces unusual DNA structure.		2004
15606999	Emerging strategies and applications of pharmacogenomics.	Human Genomics	2004
15606997	Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels.	Hum Genomics	2004
15324321	Cholesteryl ester transfer protein promoter single-nucleotide polymorphisms in Sp1-binding sites affect transcription and are associated with high-density lipoprotein cholesterol.	Clinical Genetics	2004
15522280	Role of a KCNH2 polymorphism (R1047 L) in dofetilide-induced Torsades de Pointes.	Journal of Molecular and Cellular Cardiology	2004
12955294	The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder.	Psychopharmacology	2004
12818401	Polymorphisms in the CETP gene and association with CETP mass and HDL levels.	Atherosclerosis	2003
11741249	CYP2D6 genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting.		2000