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Author Details

James E Crowe
Vanderbilt University Medical Center
1975
446
77
PMIDPaper TitleJournal TitlePublished Year
35952703Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape.Lancet Infect Dis2023
37909048Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination.Cell Host Microbe2023
37858466Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin.Cell Rep2023
37749254Host range, transmissibility and antigenicity of a pangolin coronavirus.Nat Microbiol2023
37849399Developing a Prototype Pathogen Plan and Research Priorities for the Alphaviruses.J Infect Dis2023
37704627Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses.Nat Commun2023
37516111Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.Cell Host Microbe2023
37935199SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes.Cell Rep Med2023
38039973A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection.Cell Rep Med2023
37923717Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.Nat Commun2023
37495594A highly potent human neutralizing antibody prevents vertical transmission of Rift Valley fever virus in a rat model.Nat Commun2023
37322112Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody.Nat Microbiol2023
37180140Corrigendum: Convergent antibody responses are associated with broad neutralization of hepatitis C virus.Front Immunol2023
37131834Antiviral protection by antibodies targeting the glycan cap of Ebola virus glycoprotein requires activation of the complement system.Res Sq2023
37033915Glycan masking in vaccine design: Targets, immunogens and applications.Front Immunol2023
37196061A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.Sci Transl Med2023
37029928Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes.Cell Rep2023
37029694Development of a Kinetic ELISA and Reactive B Cell Frequency Assay to Detect Respiratory Syncytial Virus Pre-Fusion F Protein-Specific Immune Responses in Infants.J Pediatric Infect Dis Soc2023
36961925Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.Proc Natl Acad Sci U S A2023
36853802Potently neutralizing human mAbs against the zoonotic pararubulavirus Sosuga virus.JCI Insight2023
36708513Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor.Cell Rep2023
36732618Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxis.Gene Ther2023
35228693Bispecific antiviral neutralizing antibodies are twice as nice.Nat Immunol2022
35710908Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine.Nat Commun2022
35676279Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.Nat Commun2022
35613596Sites of vulnerability in HCV E1E2 identified by comprehensive functional screening.Cell Rep2022
35613028Enterovirus D68 in the Anterior Horn Cells of a Child with Acute Flaccid Myelitis.N Engl J Med2022
35584193Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.PLoS Pathog2022
35583347Human Monoclonal Antibodies to Escherichia coli Outer Membrane Protein A Porin Domain Cause Aggregation but Do Not Alter <i>In Vivo</i> Bacterial Burdens in a Murine Sepsis Model.Infect Immun2022
35507649Structural mapping of antibody landscapes to human betacoronavirus spike proteins.Sci Adv2022
35544469The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta.MAbs2022
35472136An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer.J Clin Invest2022
35578733Real-time cell analysis: A high-throughput approach for testing SARS-CoV-2 antibody neutralization and escape.STAR Protoc2022
35857623A bivalent SARS-CoV-2 monoclonal antibody combination does not affect the immunogenicity of a vector-based COVID-19 vaccine in macaques.Sci Transl Med2022
35420472Isolation of a Potently Neutralizing and Protective Human Monoclonal Antibody Targeting Yellow Fever Virus.mBio2022
35780813Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized With COVID-19: A Blinded, Randomized, Placebo-Controlled Trial.Chest2022
35780162Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains.Nat Commun2022
35449420Author Correction: A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus.Nat Med2022
35588376Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency.J Clin Invest2022
36477260Computational epitope mapping of class I fusion proteins using low complexity supervised learning methods.PLoS Comput Biol2022
36516766Neutralization fingerprinting technology for characterizing polyclonal antibody responses to dengue vaccines.Cell Rep2022
36316224Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection.Adv Sci (Weinh)2022
36389818Cross-reactive neutralizing human monoclonal antibodies mapping to variable antigenic sites on the norovirus major capsid protein.Front Immunol2022
35132398A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques.Med2022
35076282The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans.Sci Transl Med2022
35046573An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies.Nat Med2022
35273142Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity.Nat Commun2022
35241839Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking.Nat Biotechnol2022
35143767Even old foes can learn sweet new tricks.Cell Host Microbe2022
35113730Human Antibodies for Viral Infections.Annu Rev Immunol2022
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Collaborators

Michael S Diamond
Washington University School of Medicine
Co-authored papers 51
Robert H Carnahan
Vanderbilt University Medical Center
Co-authored papers 51
Pavlo Gilchuk
Vanderbilt University Medical Center
Co-authored papers 50
Jens Meiler
Vanderbilt University
Co-authored papers 29
Kathryn M Edwards
Vanderbilt University Medical Center
Co-authored papers 22
Rita E Chen
Co-authored papers 19
Natalia A Kuzmina
University of Texas Medical Branch, USA Galveston National Laboratory
Co-authored papers 17
Galit Alter
Co-authored papers 15
Ian A Wilson
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 14
Ralph S Baric
University of North Carolina
Co-authored papers 14
Laura A VanBlargan
Washington University School of Medicine
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Ivelin S Georgiev
Co-authored papers 12
Sandra M Yoder
Vanderbilt University Medical Center
Co-authored papers 12
Bronwyn M Gunn
Co-authored papers 11
Cinque Soto
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John T Bates
University of Mississippi Medical Center
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Natalie J Thornburg
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Adrianus C M Boon
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Pei-Yong Shi
University of Texas Medical Branch
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Yoshihiro Kawaoka
Influenza Research Institute, University of Wisconsin
Co-authored papers 7
Terrence M Tumpey
Centers for Disease Control and Prevention.
Co-authored papers 7
Larissa B Thackray
Washington University School of Medicine
Co-authored papers 6
William B Klimstra
Co-authored papers 6
Christopher F Basler
Icahn School of Medicine at Mount Sinai
Co-authored papers 6
David M Reif
Bioinformatics Research Center, North Carolina State University
Co-authored papers 5
Jason S McLellan
Co-authored papers 5
Michael G Rossmann
Purdue University
Co-authored papers 5
Boyd L Yount
University of North Carolina at Chapel Hill
Co-authored papers 5
Isaac P Thomsen
Vanderbilt University Medical Center
Co-authored papers 5
Dan H Barouch
Co-authored papers 5
Release 1.2