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Author Details

Livia Garzia
The Research Institute of the McGill University Health Centre, McGill University
2003
52
31
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36931244Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration.Cell2023
37503309Synapse-specific diversity of distinct postsynaptic GluN2 subtypes defines transmission strength in spinal lamina I.Front Synaptic Neurosci2023
36131014Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36446943Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36471070K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas.Nat Genet2022
34045740Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.Nat Med2021
33578853The Underlying Biology and Therapeutic Vulnerabilities of Leptomeningeal Metastases in Adult Solid Cancers.Cancers (Basel)2021
34475389Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.Nat Commun2021
32286280Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.Nat Commun2020
31883407The molecular biology of medulloblastoma metastasis.Brain Pathol2020
33259802Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.Cell2020
32967858H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone.Cancer Discov2020
32675360Nailing a Fe-rocious form of cancer.Science2020
32445698Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.Cell2020
32302564Roadmap for the Emerging Field of Cancer Neuroscience.Cell2020
30771762Leptomeningeal dissemination: a sinister pattern of medulloblastoma growth.J Neurosurg Pediatr2019
31664194Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.Nature2019
31768071Stalled developmental programs at the root of pediatric brain tumors.Nat Genet2019
28575493miR miR on the wall, who's the most malignant medulloblastoma miR of them all?Neuro Oncol2018
29856958A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.Cell2018
30591080A functional genomics approach to identify pathways of drug resistance in medulloblastoma.Acta Neuropathol Commun2018
29474906A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.Cell2018
29490009Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition.Brain2018
29258295Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.Nature2018
28609654Intertumoral Heterogeneity within Medulloblastoma Subgroups.Cancer Cell2017
28475368Tailoring Medulloblastoma Treatment Through Genomics: Making a Change, One Subgroup at a Time.Annu Rev Genomics Hum Genet2017
28394352Spatial heterogeneity in medulloblastoma.Nat Genet2017
26760213Divergent clonal selection dominates medulloblastoma at recurrence.Nature2016
27960086Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.Cancer Cell2016
26976201Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.Lancet Oncol2016
25391241Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.Cancer Res2015
26351319Poly-ADP-Ribose Polymerase as a Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma and Pediatric High-Grade Astrocytoma.Mol Cancer Ther2015
26258683EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.Nat Neurosci2015
25909030Measuring the optical characteristics of medulloblastoma with optical coherence tomography.Biomed Opt Express2015
25689980Medulloblastoma subgroups remain stable across primary and metastatic compartments.Acta Neuropathol2015
24493713Cytogenetic prognostication within medulloblastoma subgroups.J Clin Oncol2014
24553142Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.Nature2014
24174164TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.Acta Neuropathol2013
22343890Clonal selection drives genetic divergence of metastatic medulloblastoma.Nature2012
22967741Spatial and temporal expressions of prune reveal a role in Müller gliogenesis during Xenopus retinal development.Gene2012
22832581Subgroup-specific structural variation across 1,000 medulloblastoma genomes.Nature2012
22411914The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma.Neuro Oncol2012
21597995PCDH10 is a candidate tumour suppressor gene in medulloblastoma.Childs Nerv Syst2011
21840481Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.Cancer Cell2011
20154719ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.Oncogene2010
19308264MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma.PLoS One2009
17906697Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility.Oncogene2008
17655525Domain mapping on the human metastasis regulator protein h-Prune reveals a C-terminal dimerization domain.Biochem J2007
17103319H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis.J Bioenerg Biomembr2006
16107646Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.J Neurosci2005
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Collaborators

Michael D Taylor
The Hospital for Sick Children
Co-authored papers 41
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 22
Nada Jabado
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 22
Xiaochong Wu
The Hospital for Sick Children
Co-authored papers 20
Stephen C Mack
St Jude Children's Research Hospital
Co-authored papers 18
Peter B Dirks
The Hospital for Sick Children, University of Toronto
Co-authored papers 17
William A Weiss
University of California san francisco
Co-authored papers 17
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 17
James T Rutka
Hospital for Sick Children
Co-authored papers 16
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 16
Betty Luu
University of Wollongong
Co-authored papers 16
Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 15
Claudia C Faria
Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN)
Co-authored papers 14
Paul A Northcott
St Jude Children's Research Hospital
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Eric Bouffet
The Hospital for Sick Children
Co-authored papers 14
Anca Sorana Morrissy
Cumming School of Medicine, University of Calgary
Co-authored papers 14
Florence M G Cavalli
Institut Curie, PSL Research University
Co-authored papers 14
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 13
Uri Tabori
Co-authored papers 13
David J H Shih
University of Texas MD Anderson Cancer Center Houston
Co-authored papers 12
Xin Wang
The Chinese University of Hong Kong, Prince of Wales Hospital
Co-authored papers 12
Jennifer A Chan
Dana-Farber Cancer Institute
Co-authored papers 11
Pasqualino De Antonellis
University of Naples
Co-authored papers 11
Timothy E Van Meter
Virginia Commonwealthy University
Co-authored papers 10
David Malkin
Hospital for Sick Children
Co-authored papers 10
Wies??awa Grajkowska
Children's Memorial Health Institute
Co-authored papers 10
Charles G Eberhart
Wilmer Eye Institute, Johns Hopkins Medical Institutions
Co-authored papers 10
Craig Daniels
The Hospital for Sick Children
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David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
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Seung-Ki Kim
Seoul National University Children's Hospital
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Release 1.2