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Author Details

Michael F Miles
Virginia Commonwealth University
1980
122
35
PMIDPaper TitleJournal TitlePublished Year
36057379Thermal antinociceptive responses to alcohol in DBA/2J and C57BL/6J inbred male and female mouse strains.Behav Brain Res2023
37098020Case-only exome variation analysis of severe alcohol dependence using a multivariate hierarchical gene clustering approach.PLoS One2023
36781202Identification of candidate genes for nicotine withdrawal in C57BL/6J ÿ DBA/2J recombinant inbred mice.Genes Brain Behav2023
34839533Chloride intracellular channel 4 (CLIC4) expression profile in the mouse medial prefrontal cortex and its regulation by ethanol.Alcohol Clin Exp Res2022
34164896Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges.Addict Biol2021
33522903GCSscore: an R package for differential gene expression analysis in Affymetrix/Thermo-Fisher whole transcriptome microarrays.BMC Genomics2021
34228751Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidation-reduction function as possible mechanism of altered sensitivity to ethanol sedation.PLoS One2021
31294817Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes.Nicotine Tob Res2020
33332381Network preservation reveals shared and unique biological processes associated with chronic alcohol abuse in NAc and PFC.PLoS One2020
33067813Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol Dependence.Alcohol Clin Exp Res2020
32469986Brain regional gene expression network analysis identifies unique interactions between chronic ethanol exposure and consumption.PLoS One2020
29316088Beyond genome-wide significance: integrative approaches to the interpretation and extension of GWAS findings for alcohol use disorder.Addict Biol2019
31766669A Novel Neighbor Housing Environment Enhances Social Interaction and Rescues Cognitive Deficits from Social Isolation in Adolescence.Brain Sci2019
30038413Chronic clozapine treatment restrains via HDAC2 the performance of mGlu2 receptor agonism in a rodent model of antipsychotic activity.Neuropsychopharmacology2019
31326461Adolescent but not adult ethanol binge drinking modulates ethanol behavioral effects in mice later in life.Pharmacol Biochem Behav2019
31211793Correction: Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption.PLoS One2019
31456662Cross-Species Co-analysis of Prefrontal Cortex Chronic Ethanol Transcriptome Responses in Mice and Monkeys.Front Mol Neurosci2019
31562845Pharmacological mechanisms of alcohol analgesic-like properties in mouse models of acute and chronic pain.Neuropharmacology2019
31017905Cross-species alcohol dependence-associated gene networks: Co-analysis of mouse brain gene expression and human genome-wide association data.PLoS One2019
31122337Connecting the Dots: Adolescent Alcohol, Enhancer RNA, and Anxiety.Biol Psychiatry2019
30401942Correction: Chronic clozapine treatment restrains via HDAC2 the performance of mGlu2 receptor agonism in a rodent model of antipsychotic activity.Neuropsychopharmacology2019
30319688Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice.Front Genet2018
29944862Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice.Neuropharmacology2018
30188517Glycogen synthase kinase 3 beta regulates ethanol consumption and is a risk factor for alcohol dependence.Neuropsychopharmacology2018
30213503Cross-species molecular dissection across alcohol behavioral domains.Alcohol2018
30209534Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice.Psychopharmacology (Berl)2018
30320886A Whole Methylome Study of Ethanol Exposure in Brain and Blood: An Exploration of the Utility of Peripheral Blood as Proxy Tissue for Brain in Alcohol Methylation Studies.Alcohol Clin Exp Res2018
27432260Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.Alcohol2017
28226201Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms.Alcohol Clin Exp Res2017
28279662In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.Neuropharmacology2017
29018328Intermittent Ethanol during Adolescence Leads to Lasting Behavioral Changes in Adulthood and Alters Gene Expression and Histone Methylation in the PFC.Front Mol Neurosci2017
27933543Integrative Analysis of Genetic, Genomic, and Phenotypic Data for Ethanol Behaviors: A Network-Based Pipeline for Identifying Mechanisms and Potential Drug Targets.Methods Mol Biol2017
27793543Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort.Alcohol2017
27838001The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort.Alcohol2017
27894806Genetic divergence in the transcriptional engram of chronic alcohol abuse: A laser-capture RNA-seq study of the mouse mesocorticolimbic system.Alcohol2017
27884493Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains.Alcohol2017
26948279Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains.Genes Brain Behav2016
26730594Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption.PLoS One2016
26727524Nicotine Enhances the Hypnotic and Hypothermic Effects of Alcohol in the Mouse.Alcohol Clin Exp Res2016
24352707Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior.Brain Struct Funct2015
26381263Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence.PLoS One2015
26259085Translating Alcohol Research: Opportunities and Challenges.Alcohol Res2015
25896098Applying the new genomics to alcohol dependence.Alcohol2015
25662840KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.Neuropsychopharmacology2015
25258021Inhibition of monoacylglycerol lipase reduces nicotine withdrawal.Br J Pharmacol2015
24289814Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.Genes Brain Behav2014
25307574Molecular and neurologic responses to chronic alcohol use.Handb Clin Neurol2014
24750073The α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies.Br J Pharmacol2014
24859201Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory.Nat Neurosci2014
24705017Genetic studies in Drosophila and humans support a model for the concerted function of CISD2, PPT1 and CLN3 in disease.Biol Open2014
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Collaborators

Robert W Williams
Mayo Clinic
Co-authored papers 16
Marcelo F Lopez
Charleston Alcohol Research Center, Medical University of South Carolina
Co-authored papers 12
Kenneth S Kendler
Virginia Commonwealth University
Co-authored papers 10
Sean P Farris
Center for Neuroscience, University of Pittsburgh
Co-authored papers 10
Brien P Riley
Virginia Commonwealth University
Co-authored papers 8
Robnet T Kerns
National Institute of Environmental Health Sciences Research Triangle Park
Co-authored papers 7
Lu Lu
University of Tennessee Health Science Center
Co-authored papers 6
Xiangning Chen
Center for Precision Health, The University of Texas Health Science Center at Houston
Co-authored papers 5
Megan K Mulligan
University of Tennessee Health Science Center.
Co-authored papers 5
Boris Tabakoff
University of Colorado Health Science Center
Co-authored papers 4
Danielle M Dick
Co-authored papers 4
Elissa J Chesler
Center for Systems Neurogenetics of Addiction at The Jackson Laboratory
Co-authored papers 4
Fazil Aliev
Co-authored papers 4
Kathleen A Grant
Oregon National Primate Research Center, Oregon Health and Science University.
Co-authored papers 4
Howard J Edenberg
Indiana University School of Medicine
Co-authored papers 3
Zhongming Zhao
Center for Precision Health, The University of Texas Health Science Center at Houston
Co-authored papers 3
Daniel H Lowenstein
University of California san francisco
Co-authored papers 3
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 3
Edwin J C G van den Oord
Co-authored papers 3
Paula L Hoffman
University of Colorado
Co-authored papers 3
Robert Hitzemann
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 3
Lindsay A Farrer
Boston University Chobanian & Avedisian School of Medicine
Co-authored papers 2
Jingchun Chen
Nevada Institute of Personalized Medicine, University of Nevada Las Vegas
Co-authored papers 2
Peilin Jia
Center for Precision Health, The University of Texas Health Science Center at Houston
Co-authored papers 2
Roy Dayne Mayfield
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin
Co-authored papers 2
John K Belknap
Oregon Health & Science University
Co-authored papers 2
James M Sikela
University of Colorado
Co-authored papers 2
Douglas B Matthews
University of Wisconsin
Co-authored papers 2
Dorret I Boomsma
Co-authored papers 1
Robert P Searles
Oregon Health & Science University
Co-authored papers 1
Release 1.2