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Author Details
Full Name
David L Epstein
Affiliation
St. Erik Eye Hospital, Karolinska Institutet
ORCID
Career Start Year
1968
Papers
236
H Index
60
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
33775926
Recurrent Neovascular Age-Related Macular Degeneration after Discontinuation of Vascular Endothelial Growth Factor Inhibitors Managed in a Treat-and-Extend Regimen.
Ophthalmol Retina
2022
32548981
Neovascular glaucoma in patients with central retinal vein occlusion: A real-life study in the anti-VEGF era.
Acta Ophthalmol
2021
33738625
Real-life study of the use of anti-VEGF therapy versus dexamethasone implant for treatment of macular edema in retinal vein occlusion.
Graefes Arch Clin Exp Ophthalmol
2021
34287097
Visual and ocular findings in a family with X-linked cone dysfunction and protanopia.
Ophthalmic Genet
2021
32433931
Defining the Optimal Dialysis Regimen for Improving Left Ventricular Structure and Function: An Urgent Need.
J Card Fail
2020
31885209
Treatment algorithm with dexamethasone intravitreal implant in patients with diabetic macular edema.
Acta Ophthalmol
2020
29624543
INJECTION FREQUENCY OF AFLIBERCEPT VERSUS RANIBIZUMAB IN A TREAT-AND-EXTEND REGIMEN FOR CENTRAL RETINAL VEIN OCCLUSION: A Randomized Clinical Trial.
Retina
2019
28323678
LONG-TIME OUTCOME IN PATIENTS TREATED WITH RANIBIZUMAB FOR DIABETIC MACULAR EDEMA: A 4-Year Study.
Retina
2018
27348601
Vitamin D Deficiency in Patients with Central Retinal Vein Occlusion: A Case Control Study.
Curr Eye Res
2017
26866528
NEAR VISION OUTCOME IN PATIENTS WITH AGE-RELATED MACULAR DEGENERATION TREATED WITH AFLIBERCEPT.
Retina
2016
27409478
Optical Coherence Tomography Angiography in Central Retinal Vein Occlusion: Correlation Between the Foveal Avascular Zone and Visual Acuity.
Invest Ophthalmol Vis Sci
2016
25777308
Seasonality and incidence of central retinal vein occlusion in Sweden: a 6-year study.
Ophthalmic Epidemiol
2015
24408980
Circumferential tensile stiffness of glaucomatous trabecular meshwork.
Invest Ophthalmol Vis Sci
2014
24304197
Emerging trabecular outflow drugs.
J Ocul Pharmacol Ther
2014
23675999
Effects of Y27632 on keratinocyte procurement and wound healing.
Clin Exp Dermatol
2013
24932460
Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure.
J Ocul Biol
2013
23918869
Soaring aspirations: lessons from my mentors and colleagues: the Weisenfeld award.
Invest Ophthalmol Vis Sci
2013
22424833
Bevacizumab for macular edema in central retinal vein occlusion: a prospective, randomized, double-masked clinical study.
Ophthalmology
2012
23272142
Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c.
PLoS One
2012
22997289
Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation.
Invest Ophthalmol Vis Sci
2012
22786899
Differential effects of trabecular meshwork stiffness on outflow facility in normal human and porcine eyes.
Invest Ophthalmol Vis Sci
2012
22902212
Benefit from bevacizumab for macular edema in central retinal vein occlusion: twelve-month results of a prospective, randomized study.
Ophthalmology
2012
22529935
Up-regulated expression of extracellular matrix remodeling genes in phagocytically challenged trabecular meshwork cells.
PLoS One
2012
22495072
Elevated levels of RhoA in the optic nerve head of human eyes with glaucoma.
J Glaucoma
2012
22562855
From discovery to the clinic: lessons learned.
Invest Ophthalmol Vis Sci
2012
22562840
Framing glaucoma questions: what are the opportunities for glaucoma treatment? A personal perspective.
Invest Ophthalmol Vis Sci
2012
20945401
MicroRNA-24 regulates the processing of latent TGFβ1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN.
J Cell Physiol
2011
21345980
Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity.
Invest Ophthalmol Vis Sci
2011
21282569
Role of miR-204 in the regulation of apoptosis, endoplasmic reticulum stress response, and inflammation in human trabecular meshwork cells.
Invest Ophthalmol Vis Sci
2011
21484753
Intravitreal bevacizumab in central retinal vein occlusion: 18-month results of a prospective clinical trial.
Eur J Ophthalmol
2011
21268081
Rho GTPase-mediated cytoskeletal organization in Schlemm's canal cells play a critical role in the regulation of aqueous humor outflow facility.
J Cell Biochem
2011
21273536
Cross-talk between miR-29 and transforming growth factor-betas in trabecular meshwork cells.
Invest Ophthalmol Vis Sci
2011
20053980
Modulation of inflammatory markers by miR-146a during replicative senescence in trabecular meshwork cells.
Invest Ophthalmol Vis Sci
2010
21139690
LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma.
Mol Vis
2010
20574010
Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress.
Invest Ophthalmol Vis Sci
2010
20631233
Characterization of cytoskeleton-enriched protein fraction of the trabecular meshwork and ciliary muscle cells.
Invest Ophthalmol Vis Sci
2010
19961849
Effects of chemical inhibition of N-WASP, a critical regulator of actin polymerization on aqueous humor outflow through the conventional pathway.
Exp Eye Res
2010
19940135
Targeting of integrin beta1 and kinesin 2alpha by microRNA 183.
J Biol Chem
2010
19027816
Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells.
Food Chem Toxicol
2009
19956414
Role of miR-29b on the regulation of the extracellular matrix in human trabecular meshwork cells under chronic oxidative stress.
Mol Vis
2009
19608543
Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells.
Invest Ophthalmol Vis Sci
2009
19782699
Alterations in microRNA expression in stress-induced cellular senescence.
Mech Ageing Dev
2009
19456251
Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits.
J Ocul Pharmacol Ther
2009
19209241
Cross-talk between TGF-beta1 and IL-6 in human trabecular meshwork cells.
Mol Vis
2009
19262744
RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival.
Mol Vis
2009
19279691
Alterations in gene expression induced by cyclic mechanical stress in trabecular meshwork cells.
Mol Vis
2009
19046967
The role of proteolytic cellular systems in trabecular meshwork homeostasis.
Exp Eye Res
2009
19001861
Potential role of lysosomal dysfunction in the pathogenesis of primary open angle glaucoma.
Autophagy
2009
18469195
Cultured porcine trabecular meshwork cells display altered lysosomal function when subjected to chronic oxidative stress.
Invest Ophthalmol Vis Sci
2008
17516712
Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma.
BioDrugs
2007
1 - 50 of 236
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row(s) 1 - 30 of 30
Collaborators
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Harvard T.H. Chan School of Public Health, Harvard University
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The Scripps Research Institute
Co-authored papers
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Alexander M Walker
Harvard T.H. Chan School of Public Health
Co-authored papers
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Santa J Tumminia
National Eye Institute
Co-authored papers
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Andrew G Lee
Center for Space Medicine, Baylor College of Medicine
Co-authored papers
2
Cynthia A Toth
Duke University School of Medicine
Co-authored papers
1
Sandre F McNeal
Co-authored papers
1
M Roy Wilson
Wayne State University
Co-authored papers
1
Abbot F Clark
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Co-authored papers
1
Joel S Schuman
NYU Grossman School of Medicine
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Cynthia Owsley
University of Alabama at Birmingham
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Christopher A Girkin
Heersink School of Medicine, University of Alabama-Birmingham
Co-authored papers
1
Gerald McGwin
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers
1
Benjamin Geiger
Co-authored papers
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Robert N Weinreb
Shiley Eye Institute, University of California San Diego
Co-authored papers
1
1 - 15