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Author Details

Ronenn Roubenoff
1987
241
81
PMIDPaper TitleJournal TitlePublished Year
36527600Pharmacokinetics and Pharmacodynamics of Bimagrumab (BYM338).2023
36446256Unsupervised machine-learning algorithms for the identification of clinical phenotypes in the osteoarthritis initiative database.Seminars in Arthritis and Rheumatism2023
37988976Efficacy and safety of iscalimab, a novel anti-CD40 monoclonal antibody, in moderate-to-severe myasthenia gravis: A phase 2 randomized study.2023
37722125Lessons Learned While Grieving.2023
35066104Reproducibility, relevance and reliability as barriers to efficient and credible biomedical technology translation.Advanced Drug Delivery Reviews2022
36038279Longitudinal Changes in MRI Muscle Morphometry and Composition in People With Inclusion Body Myositis.Neurology2022
35545258Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project).BMJ2022
36456835Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial.Nature Medicine2022
33439265Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial.JAMA network open2021
33264516Safety and pharmacokinetics of bimagrumab in healthy older and obese adults with body composition changes in the older cohort.Journal of Cachexia, Sarcopenia and Muscle2020
33442578A Roadmap to Inform Development, Validation and Approval of Digital Mobility Outcomes: The Mobilise-D Approach.Digital Biomarkers2020
32744862Effects of Interleukin-1β Inhibition on Incident Hip and Knee Replacement : Exploratory Analyses From a Randomized, Double-Blind, Placebo-Controlled Trial.Annals of Internal Medicine2020
33074327Bimagrumab vs Optimized Standard of Care for Treatment of Sarcopenia in Community-Dwelling Older Adults: A Randomized Clinical Trial.JAMA network open2020
30894455Colony-Stimulating Factor-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes.J Pharmacol Exp Ther2019
31774406Continuous Digital Monitoring of Walking Speed in Frail Elderly Patients: Noninterventional Validation Study and Longitudinal Clinical Trial.JMIR mHealth and uHealth2019
30387136Emerging Interventions for Elderly Patients-The Promise of Regenerative Medicine.Clinical Pharmacology and Therapeutics2019
30009955How soon will digital endpoints become a cornerstone for future drug development?Drug Discovery Today2019
30095981Activin Type II Receptor Blockade for Treatment of Muscle Depletion in Chronic Obstructive Pulmonary Disease. A Randomized Trial.American Journal of Respiratory and Critical Care Medicine2019
31237312Development of Pharmacotherapies for the Treatment of Sarcopenia.Journal of frailty & aging,The2019
29148045Reply to: New Hope for Sarcopenia.2018
28643356Bimagrumab improves body composition and insulin sensitivity in insulin-resistant individuals.Diabetes, Obesity and Metabolism2018
30261246The "Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies" (SPRINTT) randomized controlled trial: Case finding, screening and characteristics of eligible participants.Exp Gerontol2018
30337273Safety, tolerability, and preliminary efficacy of an IGF-1 mimetic in patients with spinal and bulbar muscular atrophy: a randomised, placebo-controlled trial.Lancet Neurology, The2018
29566437Effects of bimagrumab, an activin receptor type II inhibitor, on pituitary neurohormonal axes.Clinical Endocrinology2018
29214748Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia.Journal of Cachexia, Sarcopenia and Muscle2018
29412436Implications of ICD-10 for Sarcopenia Clinical Practice and Clinical Trials: Report by the International Conference on Frailty and Sarcopenia Research Task Force.J Frailty Aging2018
28144913The "Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies" (SPRINTT) project: advancing the care of physically frail and sarcopenic older people.Aging clinical and experimental research2017
28596451Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study.Stroke2017
28653345Treatment of Sarcopenia with Bimagrumab: Results from a Phase II, Randomized, Controlled, Proof-of-Concept Study.2017
28436937Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia.Journal of Clinical Investigation2017
28188558Rationale for a preliminary operational definition of physical frailty and sarcopenia in the SPRINTT trial.Aging Clin Exp Res2017
28155179The need of operational paradigms for frailty in older persons: the SPRINTT project.Aging clinical and experimental research2017
28160253Physical frailty and sarcopenia (PF&S): a point of view from the industry.Aging clinical and experimental research2017
28144914The "Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies" (SPRINTT) randomized controlled trial: design and methods.Aging Clin Exp Res2017
27883164Sarcopenia Trials in Specific Diseases: Report by the International Conference on Frailty and Sarcopenia Research Task Force.J Frailty Aging2016
27454226Loss of oxidative defense and potential blockade of satellite cell maturation in the skeletal muscle of patients with cancer but not in the healthy elderly.Aging2016
26366378PHARMACOLOGICAL INTERVENTIONS IN FRAILTY AND SARCOPENIA: REPORT BY THE INTERNATIONAL CONFERENCE ON FRAILTY AND SARCOPENIA RESEARCH TASK FORCE.J Frailty Aging2015
25363509Prospect for pharmacological therapies to treat skeletal muscle dysfunction.Calcified Tissue International2015
26337973Serum Leptin Levels and the Risk of Stroke: The Framingham Study.Stroke2015
24706014Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy.Neurology2014
25317071Influence of exercise on the metabolic profile caused by 28 days of bed rest with energy deficit and amino acid supplementation in healthy men.International Journal of Medical Sciences2014
25381300Treatment of sporadic inclusion body myositis with bimagrumab.Neurology2014
24404136Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle.PLoS ONE2014
24325895The "cytokine for gerontologists" has some company.2014
23784898Cardiometabolic risks during anabolic hormone supplementation in older men.Obesity (Silver Spring)2013
21748366Value of measuring muscle performance to assess changes in lean mass with testosterone and growth hormone supplementation.Eur J Appl Physiol2012
22392875Plasma phosphatidylcholine concentrations of polyunsaturated fatty acids are differentially associated with hip bone mineral density and hip fracture in older adults: the Framingham Osteoporosis Study.J Bone Miner Res2012
22623384Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults.Journal of Nutrition2012
22865205Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia.J Cachexia Sarcopenia Muscle2012
22561528Prospects for the development of effective pharmacotherapy targeted at the skeletal muscles in chronic obstructive pulmonary disease: a translational review.Thorax2012
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