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Author Details

Ian Pass
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
1998
23
16
PMIDPaper TitleJournal TitlePublished Year
37995979High-throughput screening of compounds targeting RNA editing in Trypanosoma brucei: Novel molecular scaffolds with broad trypanocidal effects.Biochem Pharmacol2024
33414172Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth.Cancer Res2021
33922601Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP).Int J Mol Sci2021
34518534The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors.Nat Commun2021
30771432Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.Cancer Lett2019
28244987Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.Nat Chem Biol2017
26265713Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1.J Biomol Screen2015
24412070Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes.Bioorg Med Chem Lett2014
22034497TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors.J Biomol Screen2012
19144821The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation.Mol Biol Cell2009
19596797Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.J Cell Sci2009
19755709Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation.Sci Signal2009
18417249A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo.Eur J Cell Biol2008
15710328The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells.Cancer Cell2005
16869750The SRC substrate Tks5, podosomes (invadopodia), and cancer cell invasion.Cold Spring Harb Symp Quant Biol2005
12534371Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids.Biochem J2003
12615925The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.J Biol Chem2003
11439092Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.Biochem J2001
11378386Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN.Curr Biol2001
11709086Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN.Biochem Soc Trans2001
10698713Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase.Biochem J2000
9811831The lipid phosphatase activity of PTEN is critical for its tumor supressor function.Proc Natl Acad Sci U S A1998
9639254The cholecystokinin-B receptor antagonist L-740,093 produces an insurmountable antagonism of CCK-4 stimulated functional response in cells expressing the human CCK-B receptor.Neuropeptides1998
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Collaborators

Sara A Courtneidge
Oregon Health & Science University
Co-authored papers 8
Fu-Yue Zeng
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Eduard Sergienko
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Anthony B Pinkerton
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Co-authored papers 4
Yongmei Feng
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Manuela Quintavalle
IRCCS Humanitas Research Hospital
Co-authored papers 2
Shu-Ichi Matsuzawa
Co-authored papers 2
Chen-Ting Ma
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Ze'ev Ronai
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Co-authored papers 2
Christian A Hassig
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Co-authored papers 2
Robert J Ardecky
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Shinji Iizuka
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Co-authored papers 1
Kyle P Gribbin
Oregon Health and Science University
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Oregon Health and Science University
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Matthew M Abelman
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Martin E Gleave
University of British Columbia
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Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
George V Thomas
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Anagha Deshpande
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Eytan Ruppin
National Cancer Institute
Co-authored papers 1
Nicholas K Tonks
University of Washington
Co-authored papers 1
Khê Hoang-Xuan
Co-authored papers 1
Eigo Suyama
Chugai Pharmaceutical Co.
Co-authored papers 1
Aniruddha J Deshpande
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Marc F Hoylaerts
Co-authored papers 1
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