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Author Details

Justin Chapman
2007
12
11
PMIDPaper TitleJournal TitlePublished Year
30061394Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in <i>Caenorhabditis elegans</i>.Proc Natl Acad Sci U S A2018
26276665Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.Blood2015
20959535Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats.Am J Physiol Endocrinol Metab2011
21178385Antisense inhibition of S6 kinase 1 produces improved glucose tolerance and is well tolerated for 4 weeks of treatment in rats.Pharmacology2011
20308074Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice.J Biol Chem2010
20704563Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).Biochem J2010
21103061Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice.PLoS ONE2010
19841271Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization.Proc Natl Acad Sci U S A2009
1978704112/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.PLoS ONE2009
18840360Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.Cell Metab2008
17921190Demonstration of proof of mechanism and pharmacokinetics and pharmacodynamic relationship with 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide (PF-915275), an inhibitor of 11 -hydroxysteroid dehydrogenase type 1, in cynomolgus monkeys.J Pharmacol Exp Ther2008
17963725Selective modulation of promoter recruitment and transcriptional activity of PPARgamma.Biochem Biophys Res Commun2007
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