Author details

Full Name

Paola Bisignano

Affiliation

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36993679	Merlin<sup>S13</sup> phosphorylation controls meningioma Wnt signaling and magnetic resonance imaging features.	Res Sq	2023
35879364	Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.	Nat Biotechnol	2022
35614225	Mitochondrial uncouplers induce proton leak by activating AAC and UCP1.	Nature	2022
34158358	SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma.	Clin Cancer Res	2021
32614861	A kinetic mechanism for enhanced selectivity of membrane transport.	PLoS Comput Biol	2020
30548443	A Triazolotriazine-Based Dual GSK-3Î²/CK-1Î´ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition.	ChemMedChem	2019
29279396	Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1.	Proc Natl Acad Sci U S A	2018
30340023	Cilia-Associated Oxysterols Activate Smoothened.	Mol Cell	2018
30532032	Inhibitor binding mode and allosteric regulation of Na<sup>+</sup>-glucose symporters.	Nat Commun	2018
29717135	Substrate-bound outward-open structure of a Na<sup>+</sup>-coupled sialic acid symporter reveals a new Na<sup>+</sup> site.	Nat Commun	2018
29507231	Conformational transitions of the sodium-dependent sugar transporter, vSGLT.	Proc Natl Acad Sci U S A	2018
26696252	Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3Î² Inhibitors.	J Med Chem	2016
26663255	Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments.	ChemMedChem	2016
27325773	Stochastic steps in secondary active sugar transport.	Proc Natl Acad Sci U S A	2016
27245612	Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.	Sci Signal	2016
25504761	Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3Î² inhibitors.	Angew Chem Int Ed Engl	2015
26347990	Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the Î¼-Opioid Receptor.	J Chem Inf Model	2015
24444037	Kinetic characterization of fragment binding in AmpC Î²-lactamase by high-throughput molecular simulations.	J Chem Inf Model	2014
25073009	Mechanistic insights into the allosteric modulation of opioid receptors by sodium ions.	Biochemistry	2014
23196990	PLI: a web-based tool for the comparison of protein-ligand interactions observed on PDB structures.	Bioinformatics	2013
23198830	In silico deconstruction of ATP-competitive inhibitors of glycogen synthase kinase-3Î².	J Chem Inf Model	2012
21936510	SERAPhiC: a benchmark for in silico fragment-based drug design.	J Chem Inf Model	2011
19781595	Molecular dynamics analysis of the wild type and dF508 mutant structures of the human CFTR-nucleotide binding domain 1.	Biochimie	2010

1 - 23 of 23

Arthur O Zalevsky

University of California san francisco

Career Start Year 2015

Number of shared co-authors 0

Michael J Robertson

Stanford University School of Medicine

Career Start Year 2015

Number of shared co-authors 1

Jacob D Durrant

University of Pittsburgh

Career Start Year 2006

Number of shared co-authors 0

Suwen Zhao

ShanghaiTech University, China iHuman Institute

Career Start Year 2006

Number of shared co-authors 2

Jianwei Che

Dana-Farber Cancer Institute

Career Start Year 2005

Number of shared co-authors 1

Elisabetta Moroni

Istituto di Scienze e Tecnologie Chimiche "Giulio Natta" - SCITEC CNR

Career Start Year 2005

Number of shared co-authors 1

Jens Carlsson

Uppsala University

Career Start Year 2004

Number of shared co-authors 0

Avner Schlessinger

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Career Start Year 2003

Number of shared co-authors 1

Noel Southall

National Center for Advancing Translational Sciences, National Institutes of Health

Career Start Year 2002

Number of shared co-authors 0

Gerald H Lushington

Inc. 16 Dekalb Pike

Career Start Year 2002

Number of shared co-authors 0

Rommie E Amaro

University of California

Career Start Year 2001

Number of shared co-authors 0

Christopher J Langmead

Monash University

Career Start Year 2000

Number of shared co-authors 1

Heather A Carlson

University of Michigan ann arbor

Career Start Year 1999

Number of shared co-authors 0

David Lagorce

INSERM

Career Start Year 1998

Number of shared co-authors 0

Rodrigo J Carbajo

Oncology R&D

Career Start Year 1997

Number of shared co-authors 0

Peter Kolb

Institut fur Pharmazeutische Chemie, Philipps-Universitat Marburg

Career Start Year 1996

Number of shared co-authors 0

Cristian G Bologa

University of New Mexico School of Medicine

Career Start Year 1995

Number of shared co-authors 0

Hualiang Jiang

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Career Start Year 1994

Number of shared co-authors 1

Tudor I Oprea

Expert Systems Inc.

Career Start Year 1993

Number of shared co-authors 0

Giorgio Colombo

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Career Start Year 1993

Number of shared co-authors 1

Howard Broughton

Lilly Research Laboratories

Career Start Year 1990

Number of shared co-authors 0

Brian K Shoichet

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 1989

Number of shared co-authors 7

Rebecca C Wade

Center for Molecular Biology (ZMBH), Heidelberg University

Career Start Year 1989

Number of shared co-authors 0

Herman W T van Vlijmen

Leiden Academic Centre for Drug Research (LACDR), Leiden University

Career Start Year 1988

Number of shared co-authors 0

Gerhard Klebe

Institut fur Pharmazeutische Chemie, Philipps-Universitat Marburg

Career Start Year 1988

Number of shared co-authors 0

Diane Joseph-McCarthy

Boston University

Career Start Year 1987

Number of shared co-authors 0

Antonio Macchiarulo

Department of Pharmaceutical Sciences, University of Perugia

Career Start Year 1986

Number of shared co-authors 0

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Career Start Year 1981

Number of shared co-authors 0

Christine Humblet

Lilly Research Laboratories

Career Start Year 1977

Number of shared co-authors 1

Jens Meiler

Vanderbilt University

Career Start Year 1954

Number of shared co-authors 0

row(s) 1 - 30 of 30

Jeff Abramson

Co-authored papers 4

David R Raleigh

University of California san francisco

Co-authored papers 2

Lakshmi A Devi

Co-authored papers 1

Jeremy F Reiter

Cardiovascular Research Institute

Co-authored papers 1

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 1

Bonne M Thompson

Co-authored papers 1

Priyadarshini Jaishankar

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Alexis Leigh Krup

Gladstone Institutes, University of California san francisco

Co-authored papers 1

Erica Stevenson

University of California san francisco

Co-authored papers 1

Stephen T Magill

Feinberg School of Medicine, Northwestern University

Co-authored papers 1

Lauro Avalos

University of California San Francisco.

Co-authored papers 1

Hyunil Jo

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 1

Ivone Gomes

Co-authored papers 1

Mihaly Mezei

Co-authored papers 1

Abrar Choudhury

University of California San Francisco

Co-authored papers 1

Tim Casey-Clyde

University of California San Francisco.

Co-authored papers 1

Matthew P Jacobson

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Danielle L Swaney

J. David Gladstone Institutes

Co-authored papers 1

Adam R Renslo

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Charlotte Eaton

University of California San Francisco.

Co-authored papers 1

Calixto-Hope G Lucas

University of California San Francisco

Co-authored papers 1

Jeffrey G McDonald

Co-authored papers 1

Chakrapani Kalyanaraman

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Monika Abedin Sigg

University of California berkeley

Co-authored papers 1

Harish N Vasudevan

University of California San Francisco

Co-authored papers 1

Javier E Villanueva-Meyer

University of California san francisco

Co-authored papers 1

Jian Jin

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Co-authored papers 1

Jonathan S Weissman

Whitehead Institute for Biomedical Research

Co-authored papers 1

Siyuan John Liu

University of California San Francisco.

Co-authored papers 1

Achla Gupta

Co-authored papers 1

1 - 30

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