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Author Details

Philip J Ebert
Lilly Research Laboratories
1993
39
26
PMIDPaper TitleJournal TitlePublished Year
36927865Clinically important alterations in pharmacogene expression in histologically severe nonalcoholic fatty liver disease.Nat Commun2023
34718468A Randomized, Placebo-Controlled Clinical Trial of Bamlanivimab and Etesevimab Together in High-Risk Ambulatory Patients With COVID-19 and Validation of the Prognostic Value of Persistently High Viral Load.Clin Infect Dis2022
36380755Towards increased accuracy and reproducibility in SARS-CoV-2 next generation sequence analysis for public health surveillance.bioRxiv2022
33475701Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial.JAMA2021
34592180Addition of ramucirumab or merestinib to standard first-line chemotherapy for locally advanced or metastatic biliary tract cancer: a randomised, double-blind, multicentre, phase 2 study.Lancet Oncol2021
34260849Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19.N Engl J Med2021
31615937Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR<sup>+</sup>/HER2<sup>-</sup> Breast Cancer.Clin Cancer Res2020
32076484A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib.Oncotarget2020
33046718Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.Sci Data2020
32913235Identifying metastasis-initiating miRNA-target regulations of colorectal cancer from expressional changes in primary tumors.Sci Rep2020
32612211Molecular dissection of CRC primary tumors and their matched liver metastases reveals critical role of immune microenvironment, EMT and angiogenesis in cancer metastasis.Sci Rep2020
31358529Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian Cancer.Cancer Res2019
31653970Genomic characterization of intrinsic and acquired resistance to cetuximab in colorectal cancer patients.Sci Rep2019
29568395Merestinib (LY2801653) inhibits neurotrophic receptor kinase (NTRK) and suppresses growth of NTRK fusion bearing tumors.Oncotarget2018
30131386Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling.Clin Cancer Res2018
30558641Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.Mol Neurodegener2018
28611205Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with <i>BRAF</i> or <i>KRAS</i> Mutations.Clin Cancer Res2017
24239560The role of cannabinoid 1 receptor expressing interneurons in behavior.Neurobiol Dis2014
25189529Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers.Cancer Res2014
24934217Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain.Mol Pain2014
24322205Modulation of behavioral networks by selective interneuronal inactivation.Mol Psychiatry2014
24408531Paenibacillus lentus sp. nov., a β-mannanolytic bacterium isolated from mixed soil samples in a selective enrichment using guar gum as the sole carbon source.Int J Syst Evol Microbiol2014
20947638N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes.J Pharmacol Exp Ther2011
20385802RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo.Proc Natl Acad Sci U S A2010
20125089Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression.Mol Psychiatry2010
19638972The organization of the transcriptional network in specific neuronal classes.Mol Syst Biol2009
17588543Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia.Biol Psychiatry2008
18834536Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice.Mol Neurodegener2008
18378158Immune transcriptome alterations in the temporal cortex of subjects with autism.Neurobiol Dis2008
17376990Amygdala gene expression correlates of social behavior in monkeys experiencing maternal separation.J Neurosci2007
17696172Disruption of cerebral cortex MET signaling in autism spectrum disorder.Ann Neurol2007
16699510RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion.Nat Neurosci2006
16996696Bacterial artificial chromosome transgenic analysis of dynamic expression patterns of regulator of G-protein signaling 4 during development. I. Cerebral cortex.Neuroscience2006
16989953Bacterial artificial chromosome transgenic analysis of dynamic expression patterns of regulator of G-protein signaling 4 during development. II. Subcortical regions.Neuroscience2006
17053076A genetic variant that disrupts MET transcription is associated with autism.Proc Natl Acad Sci U S A2006
16860780Making the case for a candidate vulnerability gene in schizophrenia: Convergent evidence for regulator of G-protein signaling 4 (RGS4).Biol Psychiatry2006
12642498Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation.Development2003
11502254Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons.Neuron2001
8312396Cloning the partial cDNAs of mu-calpain and m-calpain from porcine skeletal muscle.Biochimie1993
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Collaborators

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Fred Hutchinson Cancer Research Center
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Chongqing Aier Eye Hospital
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University of British Columbia and BC Children's Hospital
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Mayo Clinic
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Benaroya Research Institute at Virginia Mason
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The University of Texas Health Science Center at San Antonio
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F. Hoffmann-La Roche Ltd
Co-authored papers 1
Children's Hospital Oakland Research Institute
Co-authored papers 1
Benaroya Research Institute at Virginia Mason, Institute for Systems Biology, Sage Bionetworks, University of Illinois at Urbana-Champaign
Co-authored papers 1
University of Virginia
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Mayo Clinic
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University of Pittsburgh
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University of California los angeles
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Samsung Medical Center, Sungkyunkwan University School
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