Author details

Full Name

Eduardo Eyras

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36692218	Psi promotes Drosophila wing growth via direct transcriptional activation of cell cycle targets and repression of growth inhibitors.		2023
36089245	Tumor suppressor role of RBM22 in prostate cancer acting as a dual-factor regulating alternative splicing and transcription of key oncogenic genes.		2023
37645229	Hepatitis B virus serum RNA transcript isoform composition and proportion in chronic hepatitis B patients by nanopore long-read sequencing.		2023
37139545	Concepts and methods for transcriptome-wide prediction of chemical messenger RNA modifications with machine learning.		2023
34979593	Uncovering the impacts of alternative splicing on the proteome with current omics techniques.	Wiley interdisciplinary reviews. RNA	2022
35804393	RATTLE: reference-free reconstruction and quantification of transcriptomes from Nanopore sequencing.		2022
36518527	A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1.	NAR Cancer	2022
34529669	ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer.	PLoS Comput Biol	2021
34103501	Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing.	Nature Communications	2021
33547380	PACIFIC: a lightweight deep-learning classifier of SARS-CoV-2 and co-infecting RNA viruses.	Sci Rep	2021
33323527	mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4.	RNA	2020
32286305	Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome.	Nature Communications	2020
30778134	CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity.	Leukemia	2019
31783882	ReorientExpress: reference-free orientation of nanopore cDNA reads with deep learning.		2019
29592900	Genome Sequencing and RNA-Motif Analysis Reveal Novel Damaging Noncoding Mutations in Human Tumors.	Mol Cancer Res	2018
30181341	Corrigendum: Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks.	Genome Research	2018
29571299	SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions.		2018
29617666	Systematic Analysis of Splice-Site-Creating Mutations in Cancer.	Cell Rep	2018
29596423	SARNAclust: Semi-automatic detection of RNA protein binding motifs from immunoprecipitation data.	PLoS Computational Biology	2018
29155959	The discovery potential of RNA processing profiles.	Nucleic Acids Res	2018
28005460	The role of alternative splicing in cancer.	Transcription	2017
28854369	The Functional Impact of Alternative Splicing in Cancer.	Cell Rep	2017
29269732	Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.	Nat Commun	2017
27763814	The RNA-binding landscape of RBM10 and its role in alternative splicing regulation in models of mouse early development.	RNA Biol	2017
28298237	IRFinder: assessing the impact of intron retention on mammalian gene expression.	Genome Biol	2017
27535130	The prognostic potential of alternative transcript isoforms across human tumors.	Genome Medicine	2016
27197215	Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks.	Genome Research	2016
26957605	Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing.	Proceedings of the National Academy of Sciences of the United States of America	2016
27365209	The RNA-binding profile of Acinus, a peripheral component of the exon junction complex, reveals its role in splicing regulation.	RNA	2016
27317697	The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators.	Nucleic Acids Research	2016
27857118	Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers.	Nat Commun	2016
27513819	Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum.	J Neurochem	2016
26111100	AtRTD - a comprehensive reference transcript dataset resource forÂ accurate quantification of transcript-specific expression in Arabidopsis thaliana.	New Phytologist	2015
25578962	Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer.	Nucleic Acids Research	2015
25897122	The BioMart community portal: an innovative alternative to large, centralized data repositories.	Nucleic Acids Res	2015
25599992	Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB.	EMBO Journal	2015
25934638	A chromatin code for alternative splicing involving a putative association between CTCF and HP1Î± proteins.	BMC Biology	2015
26179515	Leveraging transcript quantification for fast computation of alternative splicing profiles.	RNA	2015
26169177	A semi-supervised approach uncovers thousands of intragenic enhancers differentially activated in human cells.	BMC Genomics	2015
26207626	A Quantitative Profiling Tool for Diverse Genomic Data Types Reveals Potential Associations between Chromatin and Pre-mRNA Processing.	PLoS ONE	2015
24842991	The translational landscape of the splicing factor SRSF1 and its role in mitosis.	eLife	2014
28903032	Drosha Regulates Gene Expression Independently of RNA Cleavage Function.	Cell Reports	2014
25313066	Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells.	Proc Natl Acad Sci U S A	2014
24549677	Methods to study splicing from high-throughput RNA sequencing data.	Methods in Molecular Biology	2014
24549676	Approaches to link RNA secondary structures with splicing regulation.	Methods in Molecular Biology	2014
25219497	A global regulatory mechanism for activating an exon network required for neurogenesis.	Mol Cell	2014
24813895	Regulation of FAS exon definition and apoptosis by the Ewing sarcoma protein.	Cell Reports	2014
23494383	The 5' untranslated region of the serotonin receptor 2C pre-mRNA generates miRNAs and is expressed in non-neuronal cells.	Experimental Brain Research	2013
24360955	Drosha regulates gene expression independently of RNA cleavage function.	Cell Reports	2013
23995758	The Microprocessor controls the activity of mammalian retrotransposons.	Nature Structural and Molecular Biology	2013