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Author Details

Frederick F Lang
The University of Texas M.D. Anderson Cancer Center
1984
252
74
PMIDPaper TitleJournal TitlePublished Year
37603323Development of a rabbit human glioblastoma model for testing of endovascular selective intra-arterial infusion (ESIA) of novel stem cell-based therapeutics.Neuro Oncol2024
36510640Changes in outcomes and factors associated with survival in melanoma patients with brain metastases.Neuro Oncol2023
37653141Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade.Nat Cancer2023
37540752Multiomics analyses reveal <i>DARS1-AS1</i>/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance.Sci Adv2023
37188783Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial.Nat Med2023
37082446Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles.Front Neurol2023
37379361Adjuvant Therapy with Oncolytic Adenovirus Delta-24-RGDOX After Intratumoral Adoptive T-cell Therapy Promotes Antigen Spread to Sustain Systemic Antitumor Immunity.Cancer Res Commun2023
34260721Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.Neuro Oncol2022
35708940An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma.CA Cancer J Clin2022
35767439Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma.N Engl J Med2022
35580289A Window of Opportunity to Overcome Therapeutic Failure in Neuro-Oncology.Am Soc Clin Oncol Educ Book2022
35414632Preclinical animal brain tumor models for interventional neuro-oncology.J Neurointerv Surg2022
36059614PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells.Front Oncol2022
35151844HSP90-CDC37 functions as a chaperone for the oncogenic FGFR3-TACC3 fusion.Mol Ther2022
35176144Convection Enhanced Delivery of the Oncolytic Adenovirus Delta24-RGD in Patients with Recurrent GBM: A Phase I Clinical Trial Including Correlative Studies.Clin Cancer Res2022
34996044Circumferential sulcus-guided resection technique for improved outcomes of low-grade gliomas.J Neurosurg2022
35140215Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target.Nat Commun2022
35140124Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.Clin Cancer Res2022
35083579Long term outcomes following surgery for pineal region tumors.J Neurooncol2022
34987156Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.Nat Commun2022
34824133Perfusion-guided endovascular super-selective intra-arterial infusion for treatment of malignant brain tumors.J Neurointerv Surg2022
33349682Considerations for designing preclinical cancer immune nanomedicine studies.Nat Nanotechnol2021
35937580NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors.Reports (MDPI)2021
33795384Current strategies to circumvent the antiviral immunity to optimize cancer virotherapy.J Immunother Cancer2021
33607618The history of neurosurgery at Baylor College of Medicine.J Neurosurg2021
33524949Delta-24 adenoviral therapy for glioblastoma: evolution from the bench to bedside and future considerations.Neurosurg Focus2021
33524944Intraarterial delivery of virotherapy for glioblastoma.Neurosurg Focus2021
34450587Characterization of patient-derived bone marrow human mesenchymal stem cells as oncolytic virus carriers for the treatment of glioblastoma.J Neurosurg2021
34685601Measuring the Metabolic Evolution of Glioblastoma throughout Tumor Development, Regression, and Recurrence with Hyperpolarized Magnetic Resonance.Cells2021
34771447Intrinsic Interferon Signaling Regulates the Cell Death and Mesenchymal Phenotype of Glioblastoma Stem Cells.Cancers (Basel)2021
34039636Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma.Cancer Discov2021
34214494Hitchhiking to brain tumours: stem cell delivery of oncolytic viruses.Lancet Oncol2021
34059921An immune-competent, replication-permissive Syrian Hamster glioma model for evaluating Delta-24-RGD oncolytic adenovirus.Neuro Oncol2021
34138753Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells.J Clin Invest2021
33223031Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors.Neurosurg Clin N Am2021
30799490Perilesional Resection of Glioblastoma Is Independently Associated With Improved Outcomes.Neurosurgery2020
31755915Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages.Neuro Oncol2020
31919052Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment.Cancer Discov2020
31676690Advances in endovascular neuro-oncology: endovascular selective intra-arterial (ESIA) infusion of targeted biologic therapy for brain tumors.J Neurointerv Surg2020
33241214RNAi technology targeting the <i>FGFR3-TACC3</i> fusion breakpoint: an opportunity for precision medicine.Neurooncol Adv2020
33040087Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1) promotes glioblastoma cell invasion in the brain microenvironment.Oncogene2020
33205044Impact of anesthesia and analgesia techniques on glioblastoma progression. A narrative review.Neurooncol Adv2020
33231254Endovascular Selective Intra-Arterial Infusion of Mesenchymal Stem Cells Loaded With Delta-24 in a Canine Model.Neurosurgery2020
32653026The role of resting-state functional MRI for clinical preoperative language mapping.Cancer Imaging2020
32721947Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration.JCI Insight2020
32502992Language supplementary motor area syndrome correlated with dynamic changes in perioperative task-based functional MRI activations: case report.J Neurosurg2020
32523045A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.Nat Commun2020
32299815Glioblastoma-mediated Immune Dysfunction Limits CMV-specific T Cells and Therapeutic Responses: Results from a Phase I/II Trial.Clin Cancer Res2020
30953587REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis.Neuro Oncol2019
31608328GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory.Neurooncol Adv2019
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Collaborators

The University of Texas M.D. Anderson Cancer Center, American University of Beirut
Co-authored papers 64
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 41
MD Anderson Cancer Center
Co-authored papers 37
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 34
NYU Grossman School of Medicine
Co-authored papers 33
National Cancer Institute
Co-authored papers 25
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 25
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 21
University of Texas M.D. Anderson Cancer Center
Co-authored papers 19
CIMA-Universidad de Navarra
Co-authored papers 19
Huntsman Cancer Institute, University of Utah
Co-authored papers 19
Northwestern University Feinberg School of Medicine
Co-authored papers 18
The University of Texas MD Anderson Cancer Center
Co-authored papers 12
Lund University
Co-authored papers 11
The University of Texas MD Anderson Cancer Center
Co-authored papers 10
Kumamoto University Hospital
Co-authored papers 9
Co-authored papers 9
Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine
Co-authored papers 7
Center for Global Health, School of Public Health, Nanjing Medical University
Co-authored papers 7
Department of Neurosurgery at the University of Texas MD Anderson Cancer Center
Co-authored papers 7
The University of Texas MD Anderson Cancer Center
Co-authored papers 7
Co-authored papers 7
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
The MD Anderson Cancer Center
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Falk Center for Molecular Therapeutics, Northwestern University
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Clinical Protein Science & Imaging, Biomedical Centre, Lund University
Co-authored papers 5
Washington University School of Medicine
Co-authored papers 5