Author details

Full Name

David Lagorce

Affiliation

INSERM

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37926714	Phenotypic similarity-based approach for variant prioritization for unsolved rare disease: a preliminary methodological report.	Eur J Hum Genet	2024
37953324	The Human Phenotype Ontology in 2024: phenotypes around the world.	Nucleic Acids Res	2024
33264411	The Human Phenotype Ontology in 2021.	Nucleic Acids Res	2021
32320205	Fr-PPIChem: An Academic Compound Library Dedicated to Protein-Protein Interactions.	ACS Chem Biol	2020
28775266	In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening.	Sci Rep	2017
28397808	Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitors.	Sci Rep	2017
28961788	FAF-Drugs4: free ADME-tox filtering computations for chemical biology and early stages drug discovery.	Bioinformatics	2017
28676405	Pan-assay interference compounds (PAINS) that may not be too painful for chemical biology projects.	Drug Discov Today	2017
26432833	iPPI-DB: an online database of modulators of protein-protein interactions.	Nucleic Acids Res	2016
25748546	In silico design of low molecular weight protein-protein interaction inhibitors: Overall concept and recent advances.	Prog Biophys Mol Biol	2015
25883137	FAF-Drugs3: a web server for compound property calculation and chemical library design.	Nucleic Acids Res	2015
25855812	MTiOpenScreen: a web server for structure-based virtual screening.	Nucleic Acids Res	2015
25340632	Rational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approach.	PLoS One	2014
25254076	Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.	Mol Inform	2014
23831439	One hundred thousand mouse clicks down the road: selected online resources supporting drug discovery collected over a decade.	Drug Discov Today	2013
24039991	In silico mechanistic profiling to probe small molecule binding to sulfotransferases.	PLoS One	2013
22183534	AMMOS software: method and application.	Methods Mol Biol	2012
23072744	In silico prediction of aqueous solubility: a multimodel protocol based on chemical similarity.	Mol Pharm	2012
22650260	A leap into the chemical space of protein-protein interaction inhibitors.	Curr Pharm Des	2012
21701581	Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening.	PLoS One	2011
22647207	Three-dimensional structure generators of drug-like compounds: DG-AMMOS, an open-source package.	Expert Opin Drug Discov	2011
21636592	The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections.	Bioinformatics	2011
19912625	DG-AMMOS: a new tool to generate 3d conformation of small molecules using distance geometry and automated molecular mechanics optimization for in silico screening.	BMC Chem Biol	2009
18402678	MS-DOCK: accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening.	BMC Bioinformatics	2008
18925937	AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening.	BMC Bioinformatics	2008
18816385	FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects.	BMC Bioinformatics	2008
17696871	Free resources to assist structure-based virtual ligand screening experiments.	Curr Protein Pept Sci	2007
15897896	Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion.	Oncogene	2005
12527764	Identification and functional characterization of a new member of the human Mcm protein family: hMcm8.	Nucleic Acids Res	2003
12813464	Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.	Oncogene	2003
11402072	SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.	J Cell Biol	2001
11593432	Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging.	Oncogene	2001
10216147	Permissiveness of human biliary epithelial cells to infection by hepatitis C virus.	Hepatology	1999
10369713	Epidemiological and virological analysis of couples infected with hepatitis C virus.	Gut	1999
10405237	Significance of repeatedly normal aminotransferase activities in HCV-infected patients.	J Clin Gastroenterol	1999
9722197	Impact of HBV, HCV and GBV-C/HGV on hepatocellular carcinomas in Europe: results of a European concerted action.	J Hepatol	1998

1 - 36 of 36

Eloy Felix

European Bioinformatics Institute (EMBL-EBI)

Career Start Year 2019

Number of shared co-authors 0

Giovanni Bocci

The University of New Mexico School of Medicine

Career Start Year 2016

Number of shared co-authors 10

Paola Bisignano

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Career Start Year 2010

Number of shared co-authors 0

George Papadatos

European Molecular Biology Laboratory - European Bioinformatics Institute

Career Start Year 2007

Number of shared co-authors 0

Ola Spjuth

Department of Pharmaceutical Biosciences, Uppsala University

Career Start Year 2006

Number of shared co-authors 0

Jacob D Durrant

University of Pittsburgh

Career Start Year 2006

Number of shared co-authors 0

Rajarshi Guha

Vertex Pharmaceuticals

Career Start Year 2004

Number of shared co-authors 0

Anang A Shelat

St. Jude Children's Research Hospital

Career Start Year 2003

Number of shared co-authors 0

Gerald H Lushington

Inc. 16 Dekalb Pike

Career Start Year 2002

Number of shared co-authors 0

John J Irwin

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2002

Number of shared co-authors 0

Anna Gaulton

European Bioinformatics Institute (EMBL-EBI)

Career Start Year 2002

Number of shared co-authors 0

Scott Boyer

Swedish Toxicology Sciences Research Center, Karolinska Institutet

Career Start Year 2002

Number of shared co-authors 1

Noel Southall

National Center for Advancing Translational Sciences, National Institutes of Health

Career Start Year 2002

Number of shared co-authors 2

Stephan C Sch??rer

Institute for Data Science and Computing, University of Miami

Career Start Year 1998

Number of shared co-authors 4

Niklas Blomberg

Universitat Tubingen, Institut fur Arbeitsmedizin

Career Start Year 1996

Number of shared co-authors 3

Peter Kolb

Institut fur Pharmazeutische Chemie, Philipps-Universitat Marburg

Career Start Year 1996

Number of shared co-authors 0

Andrew L Hopkins

University of Dundee

Career Start Year 1995

Number of shared co-authors 0

Cristian G Bologa

University of New Mexico School of Medicine

Career Start Year 1995

Number of shared co-authors 10

Hualiang Jiang

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Career Start Year 1994

Number of shared co-authors 0

Arya Ajay

National Center for Advancing Translational Science, 9800 Medical Center Drive

Career Start Year 1993

Number of shared co-authors 0

Tudor I Oprea

Expert Systems Inc.

Career Start Year 1993

Number of shared co-authors 10

Robert Preissner

Institute for Physiology, Charite-University Medicine Berlin

Career Start Year 1990

Number of shared co-authors 0

Brian K Shoichet

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 1989

Number of shared co-authors 0

Herman W T van Vlijmen

Leiden Academic Centre for Drug Research (LACDR), Leiden University

Career Start Year 1988

Number of shared co-authors 0

John P Overington

Institute of Cardiovascular Science, University College London

Career Start Year 1988

Number of shared co-authors 1

Andrew R Leach

European Bioinformatics Institute (EMBL-EBI)

Career Start Year 1987

Number of shared co-authors 0

Antonio Macchiarulo

Department of Pharmaceutical Sciences, University of Perugia

Career Start Year 1986

Number of shared co-authors 0

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Career Start Year 1981

Number of shared co-authors 0

Christine Humblet

Lilly Research Laboratories

Career Start Year 1977

Number of shared co-authors 0

Stephen H Bryant

National Center for Biotechnology Information

Career Start Year 1973

Number of shared co-authors 0

row(s) 1 - 30 of 30

Sebastian K??hler

Division of Emergency Medicine University of Calgary Calgary Alberta Canada.

Co-authored papers 3

Marc Hanauer

INSERM

Co-authored papers 3

Julie A McMurry

University of Colorado - Anschutz Medical Campus

Co-authored papers 2

Leigh C Carmody

Center for the Science of Therapeutics, Broad Institute of MIT and Harvard

Co-authored papers 2

Peter N Robinson

William Harvey Research Institute, Queen Mary University of London

Co-authored papers 2

Ingo Helbig

Children's Hospital of Philadelphia

Co-authored papers 2

David Lewis-Smith

Translational and Clinical Research Institute, Newcastle University

Co-authored papers 2

Yongqun He

University of Michigan Medical School ann arbor

Co-authored papers 2

Christopher J Mungall

International Society for Biocuration, Lawrence Berkeley National Laboratory, University of Edinburgh, University of Edinburgh School of Biological Sciences

Co-authored papers 2

Zafer Y??ksel

Kahramanmaras Sutcu Imam University

Co-authored papers 2

Daniel Danis

Biomedical Research Center, Slovak Academy of Sciences

Co-authored papers 2

Rosario Rizzuto

Co-authored papers 2

Christopher G Chute

Brown University, Brown University Warren Alpert Medical School, Dartmouth-Hitchcock Medical Center, Harvard School of Public Health, Johns Hopkins Medicine, Mayo Clinic Minnesota

Co-authored papers 2

Nicole Vasilevsky

Critical Path Institute

Co-authored papers 2

Ana Rath

INSERM

Co-authored papers 2

Michael Gargano

Co-authored papers 2

Nomi L Harris

Lawrence Berkely National Laboratory, Massachusetts Institute of Technology, Princeton University

Co-authored papers 2

Monica C Munoz-Torres

University of Colorado Anschutz Medical Campus

Co-authored papers 2

Melissa A Haendel

American Medical Informatics Association, Oregon Health and Science University, Oregon State University, University of Colorado Anschutz Medical Campus, University of North Carolina at Chapel Hill, University of Wisconsin-Madison

Co-authored papers 2

Hannah Blau

Co-authored papers 1

No??mi Dahan-Oliel

McGill University, Canada Shriners Hospital for Children-Canada

Co-authored papers 1

Jon R Davids

Co-authored papers 1

Matthias Griese

Co-authored papers 1

Paul Avillach

Harvard Medical School