Author details

Full Name

Michael S Lawrence

Affiliation

ORCID

Career Start Year

2001

Papers

123

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36697832	Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.	Nature	2023
38052962	Revisiting the use of structural similarity index in Hi-C.		2023
37407818	Therapy-induced APOBEC3A drives evolution of persistent cancer cells.	Nature	2023
35019938	Active RB causes visible changes in nuclear organization.	Journal of Cell Biology	2022
36210388	Single-cell transcriptomic profiling for inferring tumor origin and mechanisms of therapeutic resistance.	npj Precision Oncology	2022
34965933	Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy.	Cancer Res	2022
34452530	APOBEC Mutagenesis Is Concordant between Tumor and Viral Genomes in HPV-Positive Head and Neck Squamous Cell Carcinoma.	Viruses	2021
33707442	An extended APOBEC3A mutation signature in cancer.	Nature Communications	2021
34168046	RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer.	Clin Cancer Res	2021
33685866	Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in <i>ROS1</i> Fusion-Positive Lung Cancer.	Clin Cancer Res	2021
34203201	Dissection of <i>PIK3CA</i> Aberration for Cervical Adenocarcinoma Outcomes.	Cancers (Basel)	2021
33075810	HPV+ oropharyngeal squamous cell carcinomas from patients with two tumors display synchrony of viral genomes yet discordant mutational profiles and signatures.	Carcinogenesis	2021
33400925	Targeted degradation of the enhancer lysine acetyltransferases CBP and p300.	Cell Chemical Biology	2021
33051600	Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile.	Mod Pathol	2021
32571788	Identification of Somatically Acquired <i>BRCA1/2</i> Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer.	Clin Cancer Res	2020
32374878	Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series.	Blood Adv	2020
32064343	Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of mutation carriers.	Science advances	2020
32039742	A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells.		2020
32086345	MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer.	Clin Cancer Res	2020
32532990	Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots.	Nat Commun	2020
32802958	Small cell transformation of <i>ROS1</i> fusion-positive lung cancer resistant to ROS1 inhibition.	NPJ Precis Oncol	2020
30711375	A Code of Mono-phosphorylation Modulates the Function of RB.	Molecular Cell	2019
31690848	Huge whole-genome study of human metastatic cancers.	Nature	2019
31843922	Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma.	Proceedings of the National Academy of Sciences of the United States of America	2019
31526759	Passenger Hotspot Mutations in Cancer.	Cancer Cell	2019
31433157	GTP-Dependent Formation of Multimeric G-Quadruplexes.	ACS Chemical Biology	2019
31431505	Genome-wide mapping of regions preferentially targeted by the human DNA-cytosine deaminase APOBEC3A using uracil-DNA pulldown and sequencing.	Journal of Biological Chemistry	2019
31068700	Next-generation characterization of the Cancer Cell Line Encyclopedia.	Nature	2019
31155233	Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer.	Cell	2019
31249028	Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features.	Science	2019
29453278	Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.	Proc Natl Acad Sci U S A	2018
30500540	Cross-talk between Lysine-Modifying Enzymes Controls Site-Specific DNA Amplifications.	Cell	2018
30057114	Cross-talk between Lysine-Modifying Enzymes Controls Site-Specific DNA Amplifications.	Cell	2018
30096302	Comprehensive Characterization of Cancer Driver Genes and Mutations.	Cell	2018
29955181	Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29955182	Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29625053	Comprehensive Characterization of Cancer Driver Genes and Mutations.	Cell	2018
29625048	Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.	Cell	2018
29717118	Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair.	Nat Commun	2018
29713087	Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29650534	Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound <i>ALK</i> Mutations in ALK-Positive Lung Cancer.	Cancer Discov	2018
29200198	NetSig: network-based discovery from cancer genomes.	Nat Methods	2018
29505033	SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors.	Nature Medicine	2018
27869828	Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias.	Nat Genet	2017
28825726	A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.	Nat Genet	2017
28892075	Analysis of somatic microsatellite indels identifies driver events in human tumors.	Nat Biotechnol	2017
28658208	Recurrent and functional regulatory mutations in breast cancer.	Nature	2017
28698210	APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition.	Cancer Research	2017
27789695	Altered biochemical specificity of G-quadruplexes with mutated tetrads.	Nucleic Acids Research	2016
27348297	The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis.	Nat Genet	2016